← Leaderboards
Li-Huei Tsai
Massachusetts Institute Of Technology
$66,135,710
Attributed
$108,969,771
Total exposure
33
Grants
22
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $13.5M · FY2005–25$20M$15M$10M$5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$109,369,769 · 34
By mechanism
R01$55,348,309 · 15
RF1$22,230,274 · 7
U01$19,747,794 · 3
UH3$3,475,569 · 1
R37$3,227,710 · 1
UG3$2,484,900 · 1
Top collaborators
- Manolis Kellis25 shared
- Edward S. Boyden7 shared
- Bruce A Yankner6 shared
- Joel William Blanchard5 shared
- Alison M Goate5 shared
- Bradley T Hyman5 shared
- Rudolf Jaenisch5 shared
- William J Ray5 shared
Most similar at Massachusetts Institute Of Technology
Same institution · by research overlap
- Roger D. Kamm$16,145,384
- Mehdi Jorfi$1,204,957
Others in their field
Top investigators on “Alzheimer&Apos”
- Jose A Luchsinger · Columbia University Health Sciences$56,595,040
- Eric M Reiman · Banner Health$48,982,487
- Yadong Huang · J. David Gladstone Institutes$40,311,515
- Lindsay A. Farrer · Boston University Medical Campus$34,189,802
- David M Holtzman · Washington University$28,985,806
- Michael W Weiner · Northern California Institute Res &Educ$28,197,224
Research focus
Alzheimer&AposS DiseaseNeuronsBrainCellsAffectMouse ModelPathologyMapsInduced Pluripotent Stem CellNeurodegenerative DisordersMediatingNerve DegenerationInsightMicrogliaGeneticMolecularGenesCell TypeImpaired CognitionPathway InteractionsAmyloidLinkSignal Transduction
Grant awards (120)
The effects of Alzheimer's disease risk genes on metabolism and signaling across cell types$2,533,330
RF1 · FY2025 · AG
Mapping the vulnerable locus coeruleus pathways in aging and AD$1,861,894
U01 · FY2025 · AG
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,068,252
R01 · FY2025 · AG
Lipid imaging expansion microscopy to study Alzheimer's disease$755,727
R01 · FY2025 · AG
Cell Type and Circuit Mechanisms of Non-Invasive Brain Stimulation by Sensory Entrainment$744,126
R01 · FY2025 · NS
Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention$677,726
R01 · FY2025 · AG · contact PI
Mechanisms of pathology and neuronal hyperactivity in a memory circuit in Alzheimer's disease$631,303
R01 · FY2025 · AG
Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimerâs Disease$542,271
R01 · FY2025 · AT · contact PI
Mapping the vulnerable locus coeruleus pathways in aging and AD$1,929,195
U01 · FY2024 · AG
Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's Disease$1,585,167
U01 · FY2024 · AG · contact PI
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,135,203
R01 · FY2024 · AG
Lipid imaging expansion microscopy to study Alzheimer's disease$771,150
R01 · FY2024 · AG
Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention$704,398
R01 · FY2024 · AG · contact PI
Mechanisms of pathology and neuronal hyperactivity in a memory circuit in Alzheimer's disease$644,186
R01 · FY2024 · AG
Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimerâs Disease$600,077
R01 · FY2024 · AT · contact PI
Mapping the vulnerable locus coeruleus pathways in aging and AD$1,955,844
U01 · FY2023 · AG
Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's Disease$1,584,706
U01 · FY2023 · AG · contact PI
Construction of an Integrated Immune - Vascular Brain - Chip as a Platform for the Study, Drug Screening, and Treatments of Alzheimer's Disease$1,158,523
UH3 · FY2023 · NS · contact PI
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,080,026
R01 · FY2023 · AG
Investigating cell-type specific convergence of APOE and ABCA7 lipid dysregulation in Alzheimerâs disease$753,667
R56 · FY2023 · AG · contact PI
Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention$716,866
R01 · FY2023 · AG · contact PI
Mechanisms of pathology and neuronal hyperactivity in a memory circuit in Alzheimer's disease$644,186
R01 · FY2023 · AG
Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimerâs Disease$621,804
R01 · FY2023 · AT · contact PI
The effects of Alzheimer's disease risk genes on metabolism and signaling across cell types$3,944,334
RF1 · FY2022 · AG
Mapping the vulnerable locus coeruleus pathways in aging and AD$1,984,794
U01 · FY2022 · AG
Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's Disease$1,587,671
U01 · FY2022 · AG · contact PI
Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,294,415
R01 · FY2022 · AG
Construction of an Integrated Immune-Vascular Brain - Chip as a Platform for the Study, Drug Screening, and Treatments of Alzheimer's Disease$1,158,523
UH3 · FY2022 · NS · contact PI
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,085,125
R01 · FY2022 · AG
Manipulating Neural Oscillations with Non-Invasive Sensory Stimulation for Alzheimer's Disease Intervention$728,970
R01 · FY2022 · AG · contact PI
Mechanisms of pathology and neuronal hyperactivity in a memory circuit in Alzheimer's disease$644,186
R01 · FY2022 · AG
Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimerâs Disease$630,460
R01 · FY2022 · AT · contact PI
The Cdk5/35 Kinase$451,800
R37 · FY2022 · NS · contact PI
Cell Type and Circuit Mechanisms of Non-Invasive Brain Stimulation by Sensory Entrainment$2,572,017
R01 · FY2021 · NS
Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's Disease$1,595,511
U01 · FY2021 · AG · contact PI
Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,552,886
R01 · FY2021 · AG
Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,294,990
R01 · FY2021 · AG
Construction of an integrated immune - vascular brain - chip as a platform for the study, drug screening, and treatments of Alzheimer's disease$1,158,523
UH3 · FY2021 · NS · contact PI
Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,076,916
R01 · FY2021 · AG
Mechanisms of pathology and neuronal hyperactivity in a memory circuit in Alzheimer's disease$662,151
R01 · FY2021 · AG
Noninvasive sensory stimulation to promote glymphatic-lymphatic clearance for the treatment of Alzheimerâs Disease$637,779
R01 · FY2021 · AT · contact PI
The Cdk5/35 Kinase$451,800
R37 · FY2021 · NS · contact PI
Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia$401,374
R01 · FY2021 · NS · contact PI
Development of PU.1 Inhibitory Modulators as Novel Therapeutics for Alzheimer's Disease$1,623,635
U01 · FY2020 · AG · contact PI
Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,578,214
R01 · FY2020 · AG
Single-cell transcriptional and epigenomic dissection of Alzheimer's Disease and Related Dementias$1,345,399
U01 · FY2020 · NS
Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,295,549
R01 · FY2020 · AG
Manipulating neural oscillations with non-invasive sensory stimulation for Alzheimer's disease intervention$761,748
R56 · FY2020 · AG · contact PI
The Cdk5/35 Kinase$451,800
R37 · FY2020 · NS · contact PI
Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia$401,374
R01 · FY2020 · NS · contact PI
Construction of an integrated immune - vascular brain - chip as a platform for the study, drug screening, and treatments of Alzheimer's disease$225,900
UG3 · FY2020 · NS · contact PI
Construction of an integrated immune - vascular brain - chip as a platform for the study, drug screening, and treatments of Alzheimer's disease$2,259,000
UG3 · FY2019 · NS · contact PI
Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,610,182
R01 · FY2019 · AG
Single-cell transcriptional and epigenomic dissection of Alzheimer's Disease and Related Dementias$1,345,399
U01 · FY2019 · NS
Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,296,090
R01 · FY2019 · AG
The Cdk5/35 Kinase$467,860
R37 · FY2019 · NS · contact PI
Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia$401,374
R01 · FY2019 · NS · contact PI
Dissection of endosomal trafficking mechanisms in Alzheimer's Disease$3,613,268
RF1 · FY2018 · AG · contact PI
Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,642,247
R01 · FY2018 · AG
Single-cell transcriptional and epigenomic dissection of Alzheimer's Disease and Related Dementias$1,348,579
U01 · FY2018 · NS
Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,308,813
R01 · FY2018 · AG
Targeting a Novel Regulator of Brain Aging and Alzheimer's Disease$979,652
R01 · FY2018 · AG
The Cdk5/35 Kinase$467,860
R37 · FY2018 · NS · contact PI
Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia$401,374
R01 · FY2018 · NS · contact PI
Deciphering the Role of Kinase Signaling and Epigenetic States in a Down Syndrome Model of Alzheimer's Disease$399,998
U54 · FY2018 · HG
Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,527,396
R01 · FY2017 · AG
Targeting a Novel Regulator of Brain Aging and Alzheimer's Disease$978,427
R01 · FY2017 · AG
Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia$481,872
R01 · FY2017 · NS · contact PI
The Cdk5/35 Kinase$467,860
R37 · FY2017 · NS · contact PI
Demystifying Microglia in Aging and Alzheimer's Disease$4,028,422
RF1 · FY2016 · AG · contact PI
Cell type specific epigenetic analysis to understand complex mechanisms underlying Alzheimer's disease phenotypes$3,861,008
RF1 · FY2016 · AG · contact PI
Targeting a Novel Regulator of Brain Aging and Alzheimer's Disease$976,136
R01 · FY2016 · AG
The Cdk5/35 Kinase$468,730
R37 · FY2016 · NS · contact PI
Targeting a Novel Regulator of Brain Aging and Alzheimer's Disease$872,459
R01 · FY2015 · AG
The Epigenetics of Alzheimer's Disease$750,001
R01 · FY2015 · NS · contact PI
The Cdk5/p35 Kinase$366,406
R01 · FY2015 · NS · contact PI
Targeting a Novel Regulator of Brain Aging and Alzheimer's Disease (ADMINISTRATIVE SUPPLEMENT- SAGE)$114,059
R01 · FY2015 · AG
Alzheimer's Disease Risk Genes in Human Microglia and Neurons Derived from iPSCs$2,126,485
RF1 · FY2014 · AG · contact PI
Examination of neural circuits underlying mood disorders in Alzheimer?s disease$1,694,505
RF1 · FY2014 · AG · contact PI
Targeting a Novel Regulator of Brain Aging and Alzheimer's Disease$935,613
R01 · FY2014 · AG
The Epigenetics of Alzheimer's Disease$742,500
R01 · FY2014 · NS · contact PI
Chemical Genomic Approaches to Neurobiology of DISC1$686,937
R01 · FY2014 · MH · contact PI
The Cdk5/p35 Kinase$362,743
R01 · FY2014 · NS · contact PI
The Epigenetics of Alzheimer's Disease$723,750
R01 · FY2013 · NS · contact PI
Chemical Genomic Approaches to Neurobiology of DISC1$657,907
R01 · FY2013 · MH · contact PI
The Cdk5/p35 Kinase$353,582
R01 · FY2013 · NS · contact PI
The Epigenetics of Alzheimer's Disease$750,000
R01 · FY2012 · NS · contact PI
Chemical Genomic Approaches to Neurobiology of DISC1$696,350
R01 · FY2012 · MH · contact PI
Epigenomic Characterization of Alzheimer's Disease Neurons from iPSCs$428,922
RF1 · FY2012 · AG · contact PI
The Cdk5/p35 Kinase$366,406
R01 · FY2012 · NS · contact PI
The Epigenetics of Alzheimer's Disease$750,000
R01 · FY2011 · NS · contact PI
Chemical Genomic Approaches to Neurobiology of DISC1$675,122
R01 · FY2011 · MH · contact PI
The Cdk5/p35 Kinase$366,406
R01 · FY2011 · NS · contact PI
Chemical Genomic Approaches to Neurobiology of DISC1$698,168
R01 · FY2010 · MH · contact PI
HDAC1 Activating Compounds as Therapeutics for Neurodegenerative Disorders$409,994
RC1 · FY2010 · AG · contact PI
The Cdk5/p35 Kinase$356,879
R01 · FY2010 · NS · contact PI
The Cdk5/p35 Kinase$84,000
R01 · FY2010 · NS · contact PI
HDAC1 Activating Compounds as Therapeutics for Neurodegenerative Disorders$413,058
RC1 · FY2009 · AG · contact PI
The Cdk5/p35 Kinase$360,484
R01 · FY2009 · NS · contact PI
The Cdk5/p35 Kinase$360,484
R01 · FY2008 · NS · contact PI
The Cdk5/p35 Kinase$360,484
R01 · FY2007 · NS · contact PI
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$240,731
R01 · FY2006 · NS · contact PI
The Cdk5/p35 Kinase$237,971
R01 · FY2006 · NS · contact PI
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$158,170
R01 · FY2006 · NS · contact PI
The Cdk5/p35 Kinase$143,404
R01 · FY2006 · NS · contact PI
Fine-tuning of LIS1-Nudel Interactions$31,248
R03 · FY2006 · TW · contact PI
2006 Gordon Research Conference on Molecular and Cellular Neurobiology$15,000
R13 · FY2006 · NS · contact PI
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$408,500
R01 · FY2005 · NS
Fine-tuning of LIS1-Nudel Interactions$32,000
R03 · FY2005 · TW
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$408,500
R01 · FY2004 · NS
THE CDK5/P35 KINASE$301,000
R01 · FY2004 · GM
Fine-tuning of LIS1-Nudel Interactions$38,500
R03 · FY2004 · TW
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$465,487
R01 · FY2003 · NS
THE CDK5/P35 KINASE$301,000
R01 · FY2003 · GM
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$32,391
R01 · FY2003 · NS
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$367,650
R01 · FY2002 · NS
THE CDK5/P35 KINASE$301,000
R01 · FY2002 · GM
THE CDK5/P35 KINASE$301,000
R01 · FY2001 · GM
SIGNAL TRANSDUCTION PATHWAY MEDIATING CDK5 FUNCTION$294,343
R01 · FY2000 · NS
CDK5/P35 KINASE$199,152
R01 · FY2000 · GM