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Joseph Heitman

Duke University

$44,576,851
Attributed
$51,790,029
Total exposure
23
Grants
19
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.8M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$51,790,029 · 23

By mechanism

R01$34,503,716 · 9
T32$8,260,897 · 2
R37$4,864,407 · 1
R21$1,694,697 · 4
P01$1,604,262 · 2
R56$854,808 · 2

Most similar at Duke University

Same institution · by research overlap

Others in their field

Top investigators on “Virulence

Research focus

VirulenceCryptococcus NeoformansPathogenesisGeneticPathogenMolecularGenesInfectionPathway InteractionsComplexProteinsInsightCalcineurinSignal TransductionCryptococcusAntifungal AgentsGenomeImmunocompromised HostEvolutionMutationAnimal ModelFungusLinkCells

Grant awards (138)

RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis$728,332
R01 · FY2025 · AI · contact PI
Calcineurin signaling cascades governing Cryptococcus virulence$652,751
R01 · FY2025 · AI · contact PI
Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis$642,695
R01 · FY2025 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$558,792
R01 · FY2025 · AI
Tri-Institutional Molecular Mycology and Pathogenesis Training Program$538,364
T32 · FY2025 · AI · contact PI
RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis$726,611
R01 · FY2024 · AI · contact PI
Calcineurin signaling cascades governing Cryptococcus virulence$692,413
R01 · FY2024 · AI · contact PI
Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis$642,695
R01 · FY2024 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$575,833
R01 · FY2024 · AI
Structure, function, and evolution of the Cryptococcus MAT locus$479,352
R01 · FY2024 · AI · contact PI
Tri-Institutional Molecular Mycology and Pathogenesis Training Program$476,564
T32 · FY2024 · AI · contact PI
Malassezia and Candida auris: skin microbiome dysbiosis and de-regulation of cutaneous homeostasis$174,750
R21 · FY2024 · AI · contact PI
RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis$742,324
R01 · FY2023 · AI · contact PI
Calcineurin signaling cascades governing Cryptococcus virulence$692,521
R01 · FY2023 · AI · contact PI
Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis$642,695
R01 · FY2023 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$582,833
R01 · FY2023 · AI
Structure, function, and evolution of the Cryptococcus MAT locus$488,951
R01 · FY2023 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$437,062
T32 · FY2023 · AI · contact PI
Malassezia and Candida auris: skin microbiome dysbiosis and de-regulation of cutaneous homeostasis$224,852
R21 · FY2023 · AI · contact PI
RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis$714,221
R01 · FY2022 · AI · contact PI
Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis$642,748
R01 · FY2022 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$498,319
R01 · FY2022 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$439,427
T32 · FY2022 · AI · contact PI
Implications of mycoviral infection in Talaromyces marneffei: an analysis of human patient samples, RNAi, and hypermutation$241,500
R21 · FY2022 · AI · contact PI
Impact of RNAi and unisexual reproduction on Cryptococcus evolution, drug resistance, and pathogenesis$642,774
R01 · FY2021 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$507,459
R01 · FY2021 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$477,190
R01 · FY2021 · AI
Molecular Mycology and Pathogenesis Training Program$411,370
T32 · FY2021 · AI · contact PI
Implications of mycoviral infection in Talaromyces marneffei: an analysis of human patient samples, RNAi, and hypermutation$201,250
R21 · FY2021 · AI · contact PI
Structural Biological Development of Fungal-Specific Calcineurin Inhibitors$669,233
R56 · FY2020 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$526,575
R37 · FY2020 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$520,915
R01 · FY2020 · AI
Structure, function, and evolution of the Cryptococcus MAT locus$517,436
R01 · FY2020 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$343,402
T32 · FY2020 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$526,255
R37 · FY2019 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$496,270
R01 · FY2019 · AI
Structure, function, and evolution of the Cryptococcus MAT locus$425,840
R01 · FY2019 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$415,344
T32 · FY2019 · AI · contact PI
Crystallography and NMR-guided generation of fungal calcineurin inhibitors$269,623
P01 · FY2019 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$532,045
R01 · FY2018 · AI
Genetics of Cryptococcus sexual reproduction$530,101
R37 · FY2018 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$425,840
R01 · FY2018 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$370,925
T32 · FY2018 · AI · contact PI
Crystallography and NMR-guided generation of fungal calcineurin inhibitors$298,465
P01 · FY2018 · AI · contact PI
Structural Biological Development of Fungal-Specific Calcineurin Inhibitors$593,377
R01 · FY2017 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$541,601
R37 · FY2017 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$431,040
R01 · FY2017 · AI · contact PI
The Genetic Basis of Virulence in Cryptococcus Neoformans$386,195
R01 · FY2017 · AI
Molecular Mycology and Pathogenesis Training Program$370,516
T32 · FY2017 · AI · contact PI
Crystallography and NMR-guided generation of fungal calcineurin inhibitors$292,345
P01 · FY2017 · AI · contact PI
The Genetic Architecture of Virulence in Cryptococcus neoformans$185,575
R56 · FY2017 · AI
Molecular Mycology and Pathogenesis Training Program$4,104
T32 · FY2017 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$2,154
T32 · FY2017 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$1,024
T32 · FY2017 · AI · contact PI
Structural Biological Development of Fungal-Specific Calcineurin Inhibitors$609,599
R01 · FY2016 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$540,791
R37 · FY2016 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$435,049
R01 · FY2016 · AI · contact PI
Crystallography and NMR-guided generation of fungal calcineurin inhibitors$290,709
P01 · FY2016 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$243,022
T32 · FY2016 · AI · contact PI
Structural Biological Development of Fungal-Specific Calcineurin Inhibitors$618,104
R01 · FY2015 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$439,837
R37 · FY2015 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$431,283
R01 · FY2015 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$382,798
T32 · FY2015 · AI · contact PI
Crystallography and NMR-guided generation of fungal calcineurin inhibitors$301,626
P01 · FY2015 · AI · contact PI
Structural Biological Development of Fungal-Specific Calcineurin Inhibitors$637,517
R01 · FY2014 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$439,837
R37 · FY2014 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$386,206
T32 · FY2014 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$413,447
R37 · FY2013 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$359,305
R01 · FY2013 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$288,654
T32 · FY2013 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$451,107
R37 · FY2012 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$382,239
R01 · FY2012 · AI · contact PI
Novel Antifungal Therapeutic Approaches$344,016
R01 · FY2012 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$202,972
T32 · FY2012 · AI · contact PI
Genetics of Cryptococcus sexual reproduction$454,856
R37 · FY2011 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$382,239
R01 · FY2011 · AI · contact PI
Novel Antifungal Therapeutic Approaches$344,016
R01 · FY2011 · AI · contact PI
Molecular Mycology and Pathogenesis Training Program$317,174
T32 · FY2011 · AI · contact PI
Sexual reproduction and virulence of zygomycete fungi$193,050
R21 · FY2011 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$386,100
R01 · FY2010 · AI · contact PI
Genetics of mating and fruiting in Cryptococcus neoformans$367,781
R01 · FY2010 · AI · contact PI
Novel Antifungal Therapeutic Approaches$347,490
R01 · FY2010 · AI · contact PI
Sexual reproduction and virulence of zygomycete fungi$234,000
R21 · FY2010 · AI · contact PI
Genetic analysis of Cryptococcus neoformans virulence$415,650
R01 · FY2009 · AI · contact PI
Structure, function, and evolution of the Cryptococcus MAT locus$390,000
R01 · FY2009 · AI · contact PI
Genetics of mating and fruiting in Cryptococcus neoformans$371,495
R01 · FY2009 · AI · contact PI
Novel Antifungal Therapeutic Approaches$351,000
R01 · FY2009 · AI · contact PI
Role of Calcineurin in Fungal Virulence$5,585
R01 · FY2009 · AI · contact PI
Genetics Training Grant-Year 26$471,818
T32 · FY2008 · GM · contact PI
Genetic analysis of Cryptococcus neoformans virulence$413,973
R01 · FY2008 · AI · contact PI
Genetics of mating and fruiting in Cryptococcus neoformans$371,495
R01 · FY2008 · AI · contact PI
Novel Antifungal Therapeutic Approaches$351,000
R01 · FY2008 · AI · contact PI
Role of Calcineurin in Fungal Virulence$322,302
R01 · FY2008 · AI · contact PI
GPCR signaling cascades in Cryptococcus neoformans$191,295
R21 · FY2008 · AI · contact PI
Genetics Training Grant-Year 26$471,818
T32 · FY2007 · GM · contact PI
Genetic analysis of Cryptococcus neoformans virulence$421,769
R01 · FY2007 · AI · contact PI
Genetics of mating and fruiting in Cryptococcus neoformans$378,488
R01 · FY2007 · AI · contact PI
Role of Calcineurin in Fungal Virulence$328,545
R01 · FY2007 · AI · contact PI
GPCR signaling cascades in Cryptococcus neoformans$234,000
R21 · FY2007 · AI · contact PI
ROLE OF NOVEL KELCH REPEAT PROTEINS IN YEAST DIFFERENTIATION$768
P41 · FY2007 · RR · contact PI
Genetics of mating and fruiting in Cryptococcus neoformans$388,542
R01 · FY2006 · AI · contact PI
Genetics Training Grant-Year 26$377,454
T32 · FY2006 · GM · contact PI
Genetic analysis of Cryptococcus neoformans virulence$375,953
R01 · FY2006 · AI · contact PI
Functions of Cryptococcus neoformans mating type loci$375,953
R01 · FY2006 · AI · contact PI
Role of Calcineurin in Fungal Virulence$338,358
R01 · FY2006 · AI · contact PI
Genetic analysis of Cryptococcus neoformans virulence$27,550
R01 · FY2006 · AI · contact PI
THE YEAST AMMONIA PERMEASE MEP2$2,859
P41 · FY2006 · RR · contact PI
Functions of Cryptococcus neoformans mating type loci$385,000
R01 · FY2005 · AI
Genetics Training Grant-Year 26$377,454
T32 · FY2005 · GM
Role of Calcineurin in Fungal Virulence$346,500
R01 · FY2005 · AI
Genetic analysis of Cryptococcus neoformans virulence$327,250
R01 · FY2005 · AI
NOVEL ANTIFUNGAL DRUG TARGETS IN CRYPTOCOCCUS NEOFORMANS$321,860
R01 · FY2005 · AI
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITING$308,000
R01 · FY2005 · AI
Functions of Cryptococcus neoformans mating type loci$385,000
R01 · FY2004 · AI
Role of Calcineurin in Fungal Virulence$346,500
R01 · FY2004 · AI
GENETICS, TRAINING GRANT$316,759
T32 · FY2004 · GM
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITING$308,000
R01 · FY2004 · AI
NOVEL ANTIFUNGAL DRUG TARGETS IN CRYPTOCOCCUS NEOFORMANS$308,000
R01 · FY2004 · AI
NOVEL ANTIFUNGAL DRUG TARGETS IN CRYPTOCOCCUS NEOFORMANS$15,318
R01 · FY2004 · AI
NOVEL KELCH REPEAT PROTEINS IN YEAST DIFFERENTIATION$3,615
P41 · FY2004 · RR
Functions of Cryptococcus neoformans mating type loci$385,000
R01 · FY2003 · AI
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITING$315,615
R01 · FY2003 · AI
GENETICS, TRAINING GRANT$315,084
T32 · FY2003 · GM
NOVEL ANTIFUNGAL DRUG TARGETS IN CRYPTOCOCCUS NEOFORMANS$308,000
R01 · FY2003 · AI
Functions of Cryptococcus neoformans mating type loci$380,680
R01 · FY2002 · AI
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITING$368,986
R01 · FY2002 · AI
NOVEL ANTIFUNGAL DRUG TARGETS IN CRYPTOCOCCUS NEOFORMANS$308,000
R01 · FY2002 · AI
GENETICS, TRAINING GRANT$299,428
T32 · FY2002 · GM
ROLE OF CALCINEURIN IN CRYPTOCOCCUS NEOFORMANS VIRULENCE$282,150
R01 · FY2002 · AI
SIGNAL TRANSDUCTION PATHWAYS REGULATING VIRULENCE$0
P01 · FY2002 · AI
SIGNAL TRANSDUCTION PATHWAYS REGULATING VIRULENCE$0
P01 · FY2002 · AI
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITING$308,000
R01 · FY2001 · AI
NOVEL ANTIFUNGAL DRUG TARGETS IN CRYPTOCOCCUS NEOFORMANS$292,600
R01 · FY2001 · AI
ROLE OF CALCINEURIN IN CRYPTOCOCCUS NEOFORMANS VIRULENCE$273,932
R01 · FY2001 · AI
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITING$30,509
R01 · FY2001 · AI
SIGNAL TRANSDUCTION PATHWAYS REGULATING VIRULENCE$0
P01 · FY2001 · AI
ROLE OF CALCINEURIN IN CRYPTOCOCCUS NEOFORMANS VIRULENCE$265,953
R01 · FY2000 · AI
SIGNAL TRANSDUCTION PATHWAYS REGULATING VIRULENCE$151,494
P01 · FY2000 · AI