Mark J Zylka

Univ Of North Carolina Chapel Hill

$33,948,391

Attributed

$37,932,720

Total exposure

Grants

Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.9M · FY2007–25

$5M$3.8M$2.5M$1.3M$0

'07

'08

'09

'10

'11

'12

'13

'14

'15

'16

'17

'18

'19

'20

'21

'22

'23

'24

'25

Funding mix

By agency

NIH$39,954,220 · 21

By mechanism

R01$18,380,691 · 8

R35$5,964,210 · 1

P30$5,046,261 · 5

DP1$3,792,400 · 1

T32$3,655,783 · 1

UG3$1,508,248 · 1

Top collaborators

Most similar at Univ Of North Carolina Chapel Hill

Same institution · by research overlap

Nathaniel A Sowa$113,812
Benjamin D Philpot$13,874,681
Michael S Sidorov$1,670,012
Adam Hantman$4,244,404
Joseph Morrissey$2,834,072

Others in their field

Top investigators on “Neurons”

Hongkui Zeng · Allen Institute$106,358,289
Eric Martin McDade · Washington University$94,632,845
Ed Lein · Allen Institute$90,858,363
Randall J Bateman · Washington University$65,841,935
John Morris · Washington University$65,018,684
Paul S. Aisen · Cognition Therapeutics, Inc.$58,570,460

Research focus

NeuronsGenesMouse ModelBrainResearch PersonnelIn VivoMutationFutureNeurosciencesBehavioralAutism Spectrum DisorderTrainingNeurodevelopmental DisorderCellsBaseGeneticPainLinkAffectEffective TherapySymptomsAllelesAnimal ModelAnalgesics

Grant awards (89)

Genome editor therapy for Angelman syndrome$1,508,248

UG3 · FY2025 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2025 · ES · contact PI

Targeted high-fidelity integration of DNA elements into the genome$603,457

R01 · FY2025 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$482,469

T32 · FY2025 · NS · contact PI

Luminescence-based biosensor to non-invasively measure UBE3A activity in the brain$233,250

R21 · FY2025 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2024 · ES · contact PI

Development of a deep neural network to measure spontaneous pain from mouse facial expressions$364,782

R01 · FY2024 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$215,923

T32 · FY2024 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2023 · ES · contact PI

UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypes$648,365

R01 · FY2023 · MH · contact PI

CRISPR/Cas9-based gene therapy for Angelman syndrome$537,260

R01 · FY2023 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$535,395

T32 · FY2023 · NS · contact PI

Development of a deep neural network to measure spontaneous pain from mouse facial expressions$376,135

R01 · FY2023 · NS · contact PI

Development of a deep neural network to measure spontaneous pain from mouse facial expressions$39,687

R01 · FY2023 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2022 · ES · contact PI

UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypes$648,365

R01 · FY2022 · MH · contact PI

CRISPR/Cas9-based gene therapy for Angelman syndrome$540,720

R01 · FY2022 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$525,222

T32 · FY2022 · NS · contact PI

Development of a deep neural network to measure spontaneous pain from mouse facial expressions$376,135

R01 · FY2022 · NS · contact PI

UNC Neuroscience Center Research Cores$155,500

P30 · FY2022 · NS · contact PI

UNC Neuroscience Center Research Cores: Administrative$51,834

P30 · FY2022 · NS · contact PI

UNC Neuroscience Center Research Cores: Microscopy$51,833

P30 · FY2022 · NS · contact PI

UNC Neuroscience Center Research Cores: Bioinformatics$51,833

P30 · FY2022 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2021 · ES · contact PI

UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypes$671,160

R01 · FY2021 · MH · contact PI

CRISPR/Cas9-based gene therapy for Angelman syndrome$586,106

R01 · FY2021 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$492,489

T32 · FY2021 · NS · contact PI

UNC Neuroscience Center Research Cores$466,500

P30 · FY2021 · NS · contact PI

Development of a deep neural network to measure spontaneous pain from mouse facial expressions$362,249

R01 · FY2021 · NS · contact PI

UNC Neuroscience Center Research Cores: Microscopy$254,304

P30 · FY2021 · NS · contact PI

UNC Neuroscience Center Research Cores: Bioinformatics$184,865

P30 · FY2021 · NS · contact PI

UNC Neuroscience Center Research Cores: Administrative$27,331

P30 · FY2021 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2020 · ES · contact PI

UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypes$700,632

R01 · FY2020 · MH · contact PI

CRISPR/Cas9-based gene therapy for Angelman syndrome$569,876

R01 · FY2020 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$486,916

T32 · FY2020 · NS · contact PI

UNC Neuroscience Center Research Cores$466,500

P30 · FY2020 · NS · contact PI

Development of a deep neural network to measure spontaneous pain from mouse facial expressions$364,998

R01 · FY2020 · NS · contact PI

UNC Neuroscience Center Research Cores: Microscopy$244,423

P30 · FY2020 · NS · contact PI

UNC Neuroscience Center Research Cores: Bioinformatics$181,930

P30 · FY2020 · NS · contact PI

UNC Neuroscience Center Research Cores: Administrative$40,147

P30 · FY2020 · NS · contact PI

Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders$852,030

R35 · FY2019 · ES · contact PI

UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypes$684,940

R01 · FY2019 · MH · contact PI

CRISPR/Cas9-based gene therapy for Angelman syndrome$569,876

R01 · FY2019 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$528,731

T32 · FY2019 · NS · contact PI

UNC Neuroscience Center Research Cores$466,500

P30 · FY2019 · NS · contact PI

UNC Neuroscience Center Research Cores: Microscopy$254,303

P30 · FY2019 · NS · contact PI

Single cell transcriptional analysis of spinal cord in a neuropathic pain model$187,936

R21 · FY2019 · NS · contact PI

UNC Neuroscience Center Research Cores: Bioinformatics$184,868

P30 · FY2019 · NS · contact PI

UNC Neuroscience Center Research Cores: Administrative$27,329

P30 · FY2019 · NS · contact PI

Transcription-associated DNA damage and neurodegeneration$708,630

R56 · FY2018 · AG · contact PI

UNC Neuroscience Center Research Cores$466,500

P30 · FY2018 · NS · contact PI

Neuroscience Predoctoral Training at UNC-Chapel Hill$388,638

T32 · FY2018 · NS · contact PI

UNC Neuroscience Center Research Cores: Microscopy$254,303

P30 · FY2018 · NS · contact PI

Single cell transcriptional analysis of spinal cord in a neuropathic pain model$226,811

R21 · FY2018 · NS · contact PI

UNC Neuroscience Center Research Cores: Bioinformatics$184,868

P30 · FY2018 · NS · contact PI

UNC Neuroscience Center Research Cores: Administrative$27,329

P30 · FY2018 · NS · contact PI

The Elongation Hypothesis of Autism$760,000

DP1 · FY2017 · ES · contact PI

Lipid kinase regulation of pain signaling and sensitization$329,876

R01 · FY2017 · NS · contact PI

Identification of candidate environmental risks for autism$250,000

R56 · FY2017 · ES · contact PI

The Elongation Hypothesis of Autism$760,000

DP1 · FY2016 · ES · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$591,194

R01 · FY2016 · MH

Lipid kinase regulation of pain signaling and sensitization$329,876

R01 · FY2016 · NS · contact PI

The Elongation Hypothesis of Autism$760,000

DP1 · FY2015 · ES · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$589,741

R01 · FY2015 · MH

Lipid kinase regulation of pain signaling and sensitization$329,876

R01 · FY2015 · NS · contact PI

The Elongation Hypothesis of Autism$752,400

DP1 · FY2014 · ES · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$607,649

R01 · FY2014 · MH

Lipid kinase regulation of pain signaling and sensitization$326,577

R01 · FY2014 · NS · contact PI

The Elongation Hypothesis of Autism$760,000

DP1 · FY2013 · ES · contact PI

Harnessing ectonucleotidases to treat chronic pain$708,206

R01 · FY2013 · NS · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$678,041

R01 · FY2013 · MH

Lipid kinase regulation of pain signaling and sensitization$329,876

R01 · FY2013 · NS · contact PI

BAC Technology$180,011

P30 · FY2013 · NS · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$94,681

R01 · FY2013 · MH

Harnessing ectonucleotidases to treat chronic pain$730,301

R01 · FY2012 · NS · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$614,344

R01 · FY2012 · MH

BAC Technology$186,539

P30 · FY2012 · NS · contact PI

Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome$32,524

R01 · FY2012 · MH

Harnessing ectonucleotidases to treat chronic pain$730,500

R01 · FY2011 · NS · contact PI

Harnessing ectonucleotidases to treat chronic pain$730,702

R01 · FY2010 · NS · contact PI

Biochemical Modulation of Nociceptive Circuits$313,921

R01 · FY2010 · NS · contact PI

BAC Technology$264,263

P30 · FY2010 · NS · contact PI

Harnessing ectonucleotidases to treat chronic pain$716,790

R01 · FY2009 · NS · contact PI

Biochemical Modulation of Nociceptive Circuits$317,091

R01 · FY2009 · NS · contact PI

BAC Technology$186,539

P30 · FY2009 · NS · contact PI

Biochemical Modulation of Nociceptive Circuits$317,091

R01 · FY2008 · NS · contact PI

BAC Technology$185,909

P30 · FY2008 · NS · contact PI

Biochemical Modulation of Nociceptive Circuits$317,091

R01 · FY2007 · NS · contact PI