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Igor E Brodsky

University Of Pennsylvania

$12,419,957
Attributed
$15,549,092
Total exposure
13
Grants
11
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.2M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$15,549,092 · 13

By mechanism

R01$12,728,391 · 6
R21$2,677,321 · 6
F32$143,380 · 1

Top collaborators

Most similar at University Of Pennsylvania

Same institution · by research overlap

Others in their field

Top investigators on “Infection

Research focus

InfectionIn VivoPathogenResponseImmuneYersiniaImmune ResponseCellsInsightSignal TransductionMolecularBacterial InfectionsMediatingCell DeathInflammatoryCytokinePreventHost DefenseMacrophageAnti-Bacterial AgentsProductionBacteriaImmunityYersinia Infections

Grant awards (37)

Defining human and mouse non-canonical inflammasome responses to LPS$3,204,624
R01 · FY2025 · AI
Dissecting innate immune control of intestinal and systemic Yersinia infection$1,024,897
R01 · FY2025 · AI · contact PI
Defining the mechanism and functions of RIPK1-induced cell death in anti-bacterial immune defense$565,255
R01 · FY2023 · AI · contact PI
Lymphothrombosis in gut health and disease$406,250
R01 · FY2023 · DK
Defining mechanisms of Casp1/11-independent death triggered by clinical Salmonella Enteritidis$203,125
R21 · FY2023 · AI · contact PI
Defining the mechanism and functions of RIPK1-induced cell death in anti-bacterial immune defense$565,255
R01 · FY2022 · AI · contact PI
Lymphothrombosis in gut health and disease$406,250
R01 · FY2022 · DK
Defining mechanisms of Casp1/11-independent death triggered by clinical Salmonella Enteritidis$243,750
R21 · FY2022 · AI · contact PI
Defining the mechanism and functions of RIPK1-induced cell death in anti-bacterial immune defense$565,255
R01 · FY2021 · AI · contact PI
Defining the non-apoptotic role of Caspase-8 activity in anti-bacterial immune defense$407,486
R01 · FY2021 · AI · contact PI
Lymphothrombosis in gut health and disease$406,250
R01 · FY2021 · DK
Defining the mechanism and functions of RIPK1-induced cell death in anti-bacterial immune defense$525,005
R01 · FY2020 · AI · contact PI
Defining the non-apoptotic role of Caspase-8 activity in anti-bacterial immune defense$407,486
R01 · FY2020 · AI · contact PI
Lymphothrombosis in gut health and disease$405,000
R01 · FY2020 · DK
Defining the mechanism and functions of RIPK1-induced cell death in anti-bacterial immune defense$541,105
R01 · FY2019 · AI · contact PI
Defining the non-apoptotic role of Caspase-8 activity in anti-bacterial immune defense$407,486
R01 · FY2019 · AI · contact PI
Lymphothrombosis in gut health and disease$405,000
R01 · FY2019 · DK
Novel role of CARD19 in cell death and anti-bacterial host defense$201,250
R21 · FY2019 · AI · contact PI
Defining the non-apoptotic role of Caspase-8 activity in anti-bacterial immune defense$407,468
R01 · FY2018 · AI · contact PI
Novel role of CARD19 in cell death and anti-bacterial host defense$241,500
R21 · FY2018 · AI · contact PI
Defining the non-apoptotic role of Caspase-8 activity in anti-bacterial immune defense$407,423
R01 · FY2017 · AI · contact PI
Dissecting the mechanism of RIPK1 kinase-dependent cell death in control of Yersinia infection$208,581
R21 · FY2017 · AI · contact PI
Modulation of Inflammasome Activation by Yersinia$400,000
R01 · FY2016 · AI · contact PI
Dissecting the mechanism of RIPK1 kinase-dependent cell death in control of Yersinia infection$249,955
R21 · FY2016 · AI · contact PI
Harnessing inflammasome activation to enhance efficacy of Salmonella vaccines$204,648
R21 · FY2016 · AI · contact PI
Modulation of Inflammasome Activation by Yersinia$400,000
R01 · FY2015 · AI · contact PI
Harnessing inflammasome activation to enhance efficacy of Salmonella vaccines$244,512
R21 · FY2015 · AI · contact PI
Role of Caspase-8 in Yersinia virulence and host defense$200,000
R21 · FY2015 · AI · contact PI
Modulation of Inflammasome Activation by Yersinia$400,000
R01 · FY2014 · AI · contact PI
Role of Caspase-8 in Yersinia virulence and host defense$240,000
R21 · FY2014 · AI · contact PI
Mechanisms of Inflammasome Inhibition by Salmonella$200,000
R21 · FY2014 · AI · contact PI
Modulation of Inflammasome Activation by Yersinia$94,896
R01 · FY2014 · AI · contact PI
Modulation of Inflammasome Activation by Yersinia$376,000
R01 · FY2013 · AI · contact PI
Mechanisms of Inflammasome Inhibition by Salmonella$240,000
R21 · FY2013 · AI · contact PI
Interaction of Yersinia with dendritic cells$50,428
F32 · FY2007 · AI · contact PI
Interaction of Yersinia with dendritic cells$48,976
F32 · FY2006 · AI · contact PI
Interaction of Yersinia with dendritic cells$43,976
F32 · FY2005 · AI