← Leaderboards
Klaus H. Kaestner
University Of Pennsylvania
$80,959,526
Attributed
$152,505,255
Total exposure
34
Grants
25
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $19.7M · FY2005–25$20M$15M$10M$5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$160,951,838 · 36
By mechanism
U01$86,509,550 · 9
UC4$23,045,231 · 3
R01$19,917,473 · 7
UM1$8,753,449 · 1
P01$7,792,196 · 6
P30$6,741,954 · 5
Top collaborators
- Ali Naji17 shared
- Alvin Carter Powers7 shared
- Mark A Atkinson6 shared
- Markus Grompe6 shared
- Mark A Kay6 shared
- Philip R Streeter6 shared
- Struan F A Grant5 shared
- Daniel James Rader5 shared
Most similar at University Of Pennsylvania
Same institution · by research overlap
- James D Lewis$18,867,749
- Chi-Der Chen$3,207,363
- Eliot Peyster$1,372,484
- Joseph Anthony Fraietta$1,846,269
Others in their field
Top investigators on “Cells”
- Lawrence Corey · Fred Hutchinson Cancer Center$536,344,731
- Barton F Haynes · Duke University$457,457,619
- David Heimbrook · Leidos Biomedical Research, Inc.$454,789,509
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$299,104,942
- Dennis R. Burton · Scripps Research Institute$278,781,854
- Mary M Horowitz · Medical College Of Wisconsin$237,383,608
Research focus
CellsGenesDiabetes MellitusPhenotypeGeneticMetabolicPancreasIsletTranscription FactorMolecularGenomicsResearch PersonnelTechnologyProgramsTissuesUnited StatesResponseCell TypeInsulinPathway InteractionsAblationIn VivoFutureBase
Grant awards (165)
Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1D$8,953,305
U01 · FY2025 · DK
Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)$2,999,756
U01 · FY2025 · DK · contact PI
Utility of Random Biopsies in Inflammatory Bowel Disease$2,620,533
U01 · FY2025 · DK
Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D)$1,998,001
U01 · FY2025 · DK · contact PI
Beta cell death in early type 1 diabetes caused by innate immune response to inefficient RNA editing$1,786,925
U01 · FY2025 · DK · contact PI
The role of senescent beta cells in T1D and T2D$680,519
U01 · FY2025 · DK · contact PI
FOXL1 positive telocytes in intestinal development and homeostsis$541,989
R01 · FY2025 · DK · contact PI
Functional Genomics Core$113,705
P30 · FY2025 · DK · contact PI
Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1D$7,118,694
U01 · FY2024 · DK
The Human Pancreas Analysis Program for Type 2 Diabetes$2,880,000
U01 · FY2024 · DK · contact PI
Utility of Random Biopsies in Inflammatory Bowel Disease$2,410,980
U01 · FY2024 · DK
Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice$1,635,817
UM1 · FY2024 · DK
The role of senescent beta cells in T1D and T2D$680,519
U01 · FY2024 · DK · contact PI
FOXL1 positive telocytes in intestinal development and homeostsis$541,989
R01 · FY2024 · DK · contact PI
Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression$517,117
R01 · FY2024 · CA · contact PI
Functional Genomics Core$113,743
P30 · FY2024 · DK · contact PI
Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1D$7,177,124
U01 · FY2023 · DK
The Human Pancreas Analysis Program for Type 2 Diabetes$3,000,000
U01 · FY2023 · DK · contact PI
Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice$1,741,729
UM1 · FY2023 · DK
The role of senescent beta cells in T1D and T2D$721,344
U01 · FY2023 · DK · contact PI
Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression$533,446
R01 · FY2023 · CA · contact PI
Functional Genomics Core$113,743
P30 · FY2023 · DK · contact PI
Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1D$50,565
U01 · FY2023 · DK
Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1D$7,234,411
U01 · FY2022 · DK
The Human Pancreas Analysis Program for Type 2 Diabetes$3,000,000
U01 · FY2022 · DK · contact PI
Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice$1,777,640
UM1 · FY2022 · DK
The role of senescent beta cells in T1D and T2D$758,532
U01 · FY2022 · DK · contact PI
Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression$533,446
R01 · FY2022 · CA · contact PI
The Human Pancreas Analysis Program for Type 2 Diabetes$268,247
U01 · FY2022 · DK · contact PI
Functional Genomics Core$114,819
P30 · FY2022 · DK · contact PI
Human Pancreas Analysis Program for Type 1 Diabetes - HPAP-T1D$7,333,457
U01 · FY2021 · DK
Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice$1,843,580
UM1 · FY2021 · DK
Center for Molecular Studies in Digestive and Liver Diseases$1,207,500
P30 · FY2021 · DK
Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression$544,332
R01 · FY2021 · CA · contact PI
Regulatory cascades in gastrointestinal proliferation$396,415
R37 · FY2021 · DK · contact PI
Functional Genomics Core$137,873
P30 · FY2021 · DK · contact PI
Penn integrated Human Pancreas procurement and Analysis Program$5,569,273
UC4 · FY2020 · DK
The Human Pancreas Analysis Program for Type 2 Diabetes$3,000,000
U01 · FY2020 · DK · contact PI
Functional Interrogation of T2D-associated genes in human stem cell-derived models and mice$1,754,683
UM1 · FY2020 · DK
Center for Molecular Studies in Digestive and Liver Diseases$1,171,276
P30 · FY2020 · DK
The Human Pancreas Analysis Program for Type 2 Diabetes$940,000
U01 · FY2020 · DK · contact PI
Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression$544,332
R01 · FY2020 · CA · contact PI
Regulatory cascades in gastrointestinal proliferation$396,415
R37 · FY2020 · DK · contact PI
Functional Genomics Core$137,873
P30 · FY2020 · DK · contact PI
The Human Pancreas Analysis Program for Type 2 Diabetes$1,899,891
U01 · FY2019 · DK · contact PI
Center for Molecular Studies in Digestive and Liver Diseases$1,183,350
P30 · FY2019 · DK
Regulatory cascades in gastrointestinal proliferation$396,415
R37 · FY2019 · DK · contact PI
Innovative Genetic Approaches for Hepatic Repopulation$360,000
R01 · FY2019 · DK · contact PI
Functional Genomics Core$137,873
P30 · FY2019 · DK · contact PI
Center for Molecular Studies in Digestive and Liver Diseases$1,176,596
P30 · FY2018 · DK
Regulation and function of the MEG3 locus in human beta-cells$489,291
R01 · FY2018 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$396,415
R37 · FY2018 · DK · contact PI
Innovative Genetic Approaches for Hepatic Repopulation$360,000
R01 · FY2018 · DK · contact PI
Functional Genomics Core$137,873
P30 · FY2018 · DK · contact PI
Drivers and consequences of beta cell DNA damage in type 1 diabetes$1,672,904
UC4 · FY2017 · DK · contact PI
Regulation and function of the MEG3 locus in human beta-cells$489,291
R01 · FY2017 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$396,415
R37 · FY2017 · DK · contact PI
Innovative Genetic Approaches for Hepatic Repopulation$360,000
R01 · FY2017 · DK · contact PI
Functional Genomics Core$138,706
P30 · FY2017 · DK · contact PI
Penn integrated Human Pancreas procurement and Analysis Program$12,249,589
UC4 · FY2016 · DK
Regulation and function of the MEG3 locus in human beta-cells$489,291
R01 · FY2016 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$366,675
R37 · FY2016 · DK · contact PI
Innovative Genetic Approaches for Hepatic Repopulation$360,000
R01 · FY2016 · DK · contact PI
The Role of CREB in liver metabolism$304,333
P01 · FY2016 · DK · contact PI
Functional Genomics Core$171,989
P30 · FY2016 · DK · contact PI
Gene Targeting Core$100,846
P01 · FY2016 · DK · contact PI
Integrative Metabolic Adaptations to Enviromental and Nutritional Challenge$1,836,965
P01 · FY2015 · DK · contact PI
Regulation and function of the MEG3 locus in human beta-cells$489,291
R01 · FY2015 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$366,675
R37 · FY2015 · DK · contact PI
Innovative Genetic Approaches for Hepatic Repopulation$360,000
R01 · FY2015 · DK · contact PI
The Role of CREB in liver metabolism$313,974
P01 · FY2015 · DK · contact PI
Functional Genomics Core$171,989
P30 · FY2015 · DK · contact PI
Gene Targeting Core$103,210
P01 · FY2015 · DK · contact PI
Regulation and function of the MEG3 locus in human beta-cells$100,000
R01 · FY2015 · DK · contact PI
Epigenetic Rejuvenation of Human Beta-Cells$3,553,465
UC4 · FY2014 · DK · contact PI
Integrative Metabolic Adaptations to Enviromental and Nutritional Challenge$1,870,896
P01 · FY2014 · DK · contact PI
Regulation and function of the MEG3 locus in human beta-cells$489,291
R01 · FY2014 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$366,675
R37 · FY2014 · DK · contact PI
The Role of CREB in liver metabolism$320,016
P01 · FY2014 · DK · contact PI
Novel Sources of Transplantable Beta-cell Replacements$287,435
U01 · FY2014 · DK
Functional Genomics Core$171,989
P30 · FY2014 · DK · contact PI
Gene Targeting Core$105,504
P01 · FY2014 · DK · contact PI
Novel Sources of Transplantable Beta-cell Replacements$99,998
U01 · FY2014 · DK
Novel Sources of Transplantable Beta-cell Replacements$1,326,946
U01 · FY2013 · DK
Epigenomic Profiling of Normal and Diabetic Pancreatic Beta-Cells$538,539
R01 · FY2013 · DK · contact PI
Transcriptional Control of Pancreatic Development$385,333
R01 · FY2013 · DK · contact PI
Epigenomics of the regenerating and aging beta-cell$384,132
U01 · FY2013 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$353,842
R37 · FY2013 · DK · contact PI
The Role of CREB in liver metabolism$318,249
P01 · FY2013 · DK · contact PI
Functional Genomics Core$166,412
P30 · FY2013 · DK · contact PI
Gene Targeting Core$99,391
P01 · FY2013 · DK · contact PI
Novel Sources of Transplantable Beta-cell Replacements$1,375,235
U01 · FY2012 · DK
Epigenomic Profiling of Normal and Diabetic Pancreatic Beta-Cells$569,354
R01 · FY2012 · DK · contact PI
Epigenomics of the regenerating and aging beta-cell$399,999
U01 · FY2012 · DK · contact PI
Transcriptional Control of Pancreatic Development$399,311
R01 · FY2012 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$366,675
R37 · FY2012 · DK · contact PI
The Role of CREB in liver metabolism$334,008
P01 · FY2012 · DK · contact PI
Functional Genomics Core$174,645
P30 · FY2012 · DK · contact PI
Gene Targeting Core$110,269
P01 · FY2012 · DK · contact PI
Novel Sources of Transplantable Beta-cell Replacements$1,085,949
U01 · FY2011 · DK
Epigenomic Profiling of Normal and Diabetic Pancreatic Beta-Cells$580,803
R01 · FY2011 · DK · contact PI
Epigenomics of the regenerating and aging beta-cell$526,299
U01 · FY2011 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$464,322
R01 · FY2011 · DK · contact PI
Transcriptional Control of Pancreatic Development$399,312
R01 · FY2011 · DK · contact PI
Novel Sources of Transplantable Beta-cell Replacements$1,085,951
U01 · FY2010 · DK
Epigenomic Profiling of Normal and Diabetic Pancreatic Beta-Cells$589,478
R01 · FY2010 · DK · contact PI
Epigenomics of the regenerating and aging beta-cell$526,298
U01 · FY2010 · DK · contact PI
Genome Analyzer for the Institute of Diabetes, Obesity, and Metabolism$500,000
S10 · FY2010 · RR · contact PI
Regulatory cascades in gastrointestinal proliferation$468,997
R01 · FY2010 · DK · contact PI
Transcriptional control of pancreatic development$445,548
R01 · FY2010 · DK · contact PI
THE ROLE OF TRANSCRIPTION FACTORS IN LIVER METABOLISM$269,681
P01 · FY2010 · DK · contact PI
EMBRYONIC STEM CELL CORE$110,745
P01 · FY2010 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$101,270
R01 · FY2010 · DK · contact PI
Transcriptional control of pancreatic development$100,000
R01 · FY2010 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$459,935
R01 · FY2009 · DK · contact PI
Transcriptional control of pancreatic development$434,499
R01 · FY2009 · DK · contact PI
THE ROLE OF TRANSCRIPTION FACTORS IN LIVER METABOLISM$272,405
P01 · FY2009 · DK · contact PI
EMBRYONIC STEM CELL CORE$111,864
P01 · FY2009 · DK · contact PI
Regulatory cascades in gastrointestinal proliferation$441,957
R01 · FY2008 · DK · contact PI
Transcriptional control of pancreatic development$332,621
R01 · FY2008 · DK · contact PI
THE ROLE OF TRANSCRIPTION FACTORS IN LIVER METABOLISM$272,405
P01 · FY2008 · DK · contact PI
EMBRYONIC STEM CELL CORE$111,864
P01 · FY2008 · DK · contact PI
Liver Biology, Development and Disease$15,000
R13 · FY2008 · DK · contact PI
Development of C57BL/6 ES cell technology for high thoughput use.$659,999
U01 · FY2007 · DA · contact PI
Regulatory cascades in gastrointestinal proliferation$377,327
R01 · FY2007 · DK · contact PI
Transcriptional control of pancreatic development$339,408
R01 · FY2007 · DK · contact PI
THE ROLE OF TRANSCRIPTION FACTORS IN LIVER METABOLISM$279,015
P01 · FY2007 · DK · contact PI
EMBRYONIC STEM CELL CORE$114,576
P01 · FY2007 · DK · contact PI
FUNCTIONAL GENOMICS OF THE BETA-CELL$100,000
U01 · FY2007 · DK · contact PI
FUNCTIONAL GENOMICS OF THE BETA-CELL$2,111,099
U01 · FY2006 · DK · contact PI
Development of C57BL/6 ES cell technology for high thoughput use.$560,000
U01 · FY2006 · DA · contact PI
Transcriptional control of pancreatic development$349,545
R01 · FY2006 · DK · contact PI
Expression profiling of human islets$348,245
R21 · FY2006 · DK · contact PI
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$323,432
R01 · FY2006 · DK · contact PI
THE ROLE OF TRANSCRIPTION FACTORS IN LIVER METABOLISM$314,167
P01 · FY2006 · DK · contact PI
EMBRYONIC STEM CELL CORE$117,813
P01 · FY2006 · DK · contact PI
FUNCTIONAL GENOMICS OF THE BETA-CELL$2,052,934
U01 · FY2005 · DK
Transcriptional control of pancreatic development$357,958
R01 · FY2005 · DK
Expression profiling of human islets$356,625
R21 · FY2005 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$338,830
U01 · FY2005 · DK
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$331,216
R01 · FY2005 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$1,993,142
U01 · FY2004 · DK
Transcriptional control of pancreatic development$357,958
R01 · FY2004 · DK
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$331,216
R01 · FY2004 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$124,075
U01 · FY2004 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$1,749,404
U01 · FY2003 · DK
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$331,216
R01 · FY2003 · DK
FUNCTION OF A GROWTH INDUCED GENE IN LIVER REGENERATION$292,720
R01 · FY2003 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$223,341
U01 · FY2003 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$185,681
U01 · FY2003 · DK
FUNCTIONAL GENOMICS OF THE BETA-CELL$1,800,000
U01 · FY2002 · DK
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$351,276
R01 · FY2002 · DK
TRANSCRIPTIONAL CONTROL OF PANCREATIC DEVELOPMENT$289,304
R01 · FY2002 · DK
Transcriptional regulation of Liver Metabolism by HNF3$0
P01 · FY2002 · DK
Core--Functional Genomics Core$0
P30 · FY2002 · DK
Core--Embryonic Stem Cell Core$0
P01 · FY2002 · DK
FUNCTIONAL GENOMICS OF THE DEVELOPING ENDOCRINE PANCREAS$1,961,250
R24 · FY2001 · DK
TRANSCRIPTIONAL CONTROL OF PANCREATIC DEVELOPMENT$280,877
R01 · FY2001 · DK
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$262,290
R01 · FY2001 · DK
Transcriptional regulation of Liver Metabolism by HNF3$0
P01 · FY2001 · DK
Core--Embryonic Stem Cell Core$0
P01 · FY2001 · DK
FUNCTIONAL GENOMICS OF THE DEVELOPING ENDOCRINE PANCREAS$1,054,399
R24 · FY2000 · DK
TRANSCRIPTIONAL CONTROL OF PANCREATIC DEVELOPMENT$272,695
R01 · FY2000 · DK
REGULATORY CASCADES IN GASTROINTESTINAL PROLIFERATION$254,650
R01 · FY2000 · DK
FUNCTIONAL GENOMICS OF THE DEVELOPING ENDOCRINE PANCREAS$153,849
R24 · FY2000 · DK