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L Darryl Quarles

Duke University

$19,109,320
Attributed
$19,853,101
Total exposure
15
Grants
13
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.5M · FY200523
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23

Funding mix

By agency

NIH$19,853,101 · 15

By mechanism

R01$17,557,195 · 9
R61$752,128 · 1
T32$544,120 · 2
R33$380,000 · 1
R56$370,000 · 1
R41$249,658 · 1

Top collaborators

Most similar at Duke University

Same institution · by research overlap

Others in their field

Top investigators on “Osteoblasts

Research focus

OsteoblastsMediatingHomeostasisOsteogenesisComplexIn VivoIn VitroBoneLinkCellsReceptorLeadMolecularGeneticOsteocalcinPathway InteractionsResponseBaseSignal TransductionPhenotypeRegulationKidneyPlayMetabolism

Grant awards (64)

Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.$249,658
R41 · FY2023 · AG · contact PI
Genetic and Environmental Determinants of GPRC6A Regulation of Energy Metabolism Using Genetically Engineered Mice and Systems Biology$495,854
R01 · FY2022 · DK · contact PI
Genetic and Environmental Determinants of GPRC6A Regulation of Energy Metabolism Using Genetically Engineered Mice and Systems Biology$495,854
R01 · FY2021 · DK · contact PI
Skeletal Functions of Polycystins and TAZ$324,368
R01 · FY2021 · AR · contact PI
Optimization of Novel Small Molecules to Antagonize FGF-23$304,000
R01 · FY2021 · DK · contact PI
Genetic and Environmental Determinants of GPRC6A Regulation of Energy Metabolism Using Genetically Engineered Mice and Systems Biology$495,854
R01 · FY2020 · DK · contact PI
Polycystins/TAZ as a novel therapeutic target to treat osteoporosis$380,000
R33 · FY2020 · AR · contact PI
Skeletal Functions of Polycystins and TAZ$334,400
R01 · FY2020 · AR · contact PI
Optimization of Novel Small Molecules to Antagonize FGF-23$304,000
R01 · FY2020 · DK · contact PI
Polycystins/TAZ as a novel therapeutic target to treat osteoporosis$372,634
R61 · FY2019 · AR · contact PI
Skeletal Functions of Polycystins and TAZ$334,400
R01 · FY2019 · AR · contact PI
Optimization of Novel Small Molecules to Antagonize FGF-23$304,000
R01 · FY2019 · DK · contact PI
Polycystins/TAZ as a novel therapeutic target to treat osteoporosis$379,494
R61 · FY2018 · AR · contact PI
Skeletal Functions of Polycystins and TAZ$300,960
R01 · FY2018 · AR · contact PI
Regulation and Function of FGF23$364,967
R01 · FY2016 · AR · contact PI
Discovery of an Osteocalcin Sensing GPCR Regulating Beta-Cell Function$345,000
R01 · FY2016 · DK · contact PI
Regulation and Function of FGF23$364,967
R01 · FY2015 · AR · contact PI
Discovery of an Osteocalcin Sensing GPCR Regulating Beta-Cell Function$345,000
R01 · FY2015 · DK · contact PI
Regulation and Function of FGF23$357,668
R01 · FY2014 · AR · contact PI
Discovery of an Osteocalcin Sensing GPCR Regulating Beta-Cell Function$345,000
R01 · FY2014 · DK · contact PI
Extrarenal Functions of Polycystin-1$304,029
R01 · FY2014 · DK · contact PI
Regulation and Function of FGF23$150,000
R01 · FY2014 · AR · contact PI
Regulation and Function of FGF23$346,718
R01 · FY2013 · AR · contact PI
Discovery of an Osteocalcin Sensing GPCR Regulating Beta-Cell Function$345,000
R01 · FY2013 · DK · contact PI
Extrarenal Functions of Polycystin-1$293,388
R01 · FY2013 · DK · contact PI
Regulation and Function of FGF23$364,965
R01 · FY2012 · AR · contact PI
Extrarenal Functions of Polycystin-1$304,029
R01 · FY2012 · DK · contact PI
Extrarenal Functions of Polycystin-1$304,029
R01 · FY2011 · DK · contact PI
Extrarenal Functions of Polycystin-1$370,000
R01 · FY2010 · DK · contact PI
Regulation and Function of FGF23$370,000
R56 · FY2009 · AR · contact PI
EXTRACELLULAR CALCIUM-SENSING RECEPTORS IN OSTEOBLASTS$272,804
R01 · FY2009 · AR · contact PI
EXTRACELLULAR CALCIUM-SENSING RECEPTORS IN OSTEOBLASTS$6,006
R01 · FY2009 · AR · contact PI
Pathogenesis of XLH/Hyp: Role of Phex MEPE and FGF23$300,509
R01 · FY2008 · AR · contact PI
EXTRACELLULAR CALCIUM-SENSING RECEPTORS IN OSTEOBLASTS$276,967
R01 · FY2008 · AR · contact PI
University of Kansas Training Grant in Nephrology$126,487
T32 · FY2008 · DK · contact PI
DIFFERENTIAL FUNCTION AND REGULATION OF RUNX2 ISOFORMS$311,869
R01 · FY2007 · AR · contact PI
Pathogenesis of XLH/Hyp: Role of Phex MEPE and FGF23$306,642
R01 · FY2007 · AR · contact PI
EXTRACELLULAR CALCIUM-SENSING RECEPTORS IN OSTEOBLASTS$282,619
R01 · FY2007 · AR · contact PI
University of Kansas Training Grant in Nephrology$120,020
T32 · FY2007 · DK · contact PI
DIFFERENTIAL FUNCTION AND REGULATION OF RUNX2 ISOFORMS$321,183
R01 · FY2006 · AR · contact PI
Pathogenesis of XLH/Hyp: Role of Phex MEPE and FGF23$315,800
R01 · FY2006 · AR · contact PI
EXTRACELLULAR CALCIUM-SENSING RECEPTORS IN OSTEOBLASTS$291,060
R01 · FY2006 · AR · contact PI
University of Kansas Training Grant in Nephrology$123,079
T32 · FY2006 · DK · contact PI
DIFFERENTIAL FUNCTION AND REGULATION OF RUNX2 ISOFORMS$356,475
R01 · FY2005 · AR
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$349,125
R01 · FY2005 · AR
Pathogenesis of XLH/Hyp: Role of Phex MEPE and FGF23$323,400
R01 · FY2005 · AR
DIFFERENTIAL FUNCTION AND REGULATION OF RUNX2 ISOFORMS$356,475
R01 · FY2004 · AR
Pathogenesis of XLH/Hyp: Role of Phex MEPE and FGF23$323,400
R01 · FY2004 · AR
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$285,915
R01 · FY2004 · AR
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$66,220
R01 · FY2004 · AR
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$365,750
R01 · FY2003 · AR
PEX FUNCTION IN OSTEOBLASTS$333,800
R01 · FY2003 · AR
DIFFERENTIAL FUNCTION AND REGULATION OF RUNX2 ISOFORMS$257,728
R01 · FY2003 · AR
DIFFERENTIAL FUNCTION AND REGULATION OF RUNX2 ISOFORMS$103,450
R01 · FY2003 · AR
GENETICS OF FAMILIAL FOCAL SEGMENTAL GLOMERULOSCLEROSIS$389,141
R01 · FY2002 · DK
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$365,750
R01 · FY2002 · AR
PEX FUNCTION IN OSTEOBLASTS$327,161
R01 · FY2002 · AR
GENETICS OF FAMILIAL FOCAL SEGMENTAL GLOMERULOSCLEROSIS$377,807
R01 · FY2001 · DK
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$365,750
R01 · FY2001 · AR
PEX FUNCTION IN OSTEOBLASTS$320,720
R01 · FY2001 · AR
GENETICS OF FAMILIAL FOCAL SEGMENTAL GLOMERULOSCLEROSIS$366,804
R01 · FY2000 · DK
PHARMACOLOGICALLY INDUCED NEO-OSTEOGENESIS$326,442
R01 · FY2000 · AR
PEX FUNCTION IN OSTEOBLASTS$311,973
R01 · FY2000 · AR
ENDOCRINOLOGY AND DIABETES TRAINING PROGRAM$174,534
T32 · FY2000 · DK