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Hiten D Madhani

University Of California, San Francisco

$33,160,600
Attributed
$35,634,662
Total exposure
25
Grants
22
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.5M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$35,634,662 · 25

By mechanism

R01$34,297,161 · 11
R21$887,500 · 2
R56$376,607 · 1
P41$73,394 · 11

Top collaborators

Most similar at University Of California, San Francisco

Same institution · by research overlap

Others in their field

Top investigators on “Genes

Research focus

GenesSaccharomyces CerevisiaeProteinsMutantSignal TransductionCryptococcus NeoformansMolecularYeastsPathogenGenomeIn VivoCellsVirulencePathway InteractionsIn VitroGeneticSiteKnock-OutProductionMycosesResponseMalignant NeoplasmsGrowthGene Expression

Grant awards (93)

Cryptococcus genomic resources$1,482,838
R01 · FY2025 · AI · contact PI
Manipulation of macrophage polarization by a fungal meningitis pathogen$1,285,692
R01 · FY2025 · AI · contact PI
Deciphering the significance of pathogen genetic variation and evolution$690,558
R01 · FY2025 · AI · contact PI
Exploiting a high-precision phenotypic map to illuminate environmental sensing by a fungal meningitis pathogen$616,588
R01 · FY2025 · AI · contact PI
Mechanisms of Gene Expression$415,863
R01 · FY2025 · GM · contact PI
Cryptococcus genomic resources$751,663
R01 · FY2024 · AI · contact PI
Deciphering the significance of pathogen genetic variation and evolution$726,574
R01 · FY2024 · AI · contact PI
Manipulation of macrophage polarization by a fungal meningitis pathogen$642,846
R01 · FY2024 · AI · contact PI
Mechanisms of Gene Expression$415,863
R01 · FY2024 · GM · contact PI
Deciphering a novel lipid-based mechanism of innate immune modulation$201,875
R21 · FY2024 · AI
Cryptococcus genomic resources$752,737
R01 · FY2023 · AI · contact PI
Manipulation of macrophage polarization by a fungal meningitis pathogen$642,846
R01 · FY2023 · AI · contact PI
Mechanisms of Gene Expression$415,863
R01 · FY2023 · GM · contact PI
Deciphering a novel lipid-based mechanism of innate immune modulation$242,250
R21 · FY2023 · AI
Cryptococcus genomic resources$763,656
R01 · FY2022 · AI · contact PI
Manipulation of macrophage polarization by a fungal meningitis pathogen$642,846
R01 · FY2022 · AI · contact PI
Mechanisms of Gene Silencing$386,854
R01 · FY2022 · GM · contact PI
Rapid production of SARS-CoV-2 molecular clones using CRISPR-based yeast recombineering$636,859
R01 · FY2021 · AI · contact PI
Cryptococcus knockout and tag resource$619,013
R01 · FY2021 · AI · contact PI
Mechanisms of Gene Silencing$386,854
R01 · FY2021 · GM · contact PI
Intracellular Recognition of Fungi by the Innate Immune System$201,875
R21 · FY2021 · AI · contact PI
Cryptococcus knockout and tag resource$632,795
R01 · FY2020 · AI · contact PI
Rapid production of SARS-CoV-2 molecular clones using CRISPR-based yeast recombineering$620,877
R01 · FY2020 · AI · contact PI
Mechanisms of Gene Silencing$388,314
R01 · FY2020 · GM · contact PI
Intracellular Recognition of Fungi by the Innate Immune System$241,500
R21 · FY2020 · AI · contact PI
Cryptococcus knockout and tag resource$632,795
R01 · FY2019 · AI · contact PI
Mechanisms of Gene Silencing$396,593
R01 · FY2019 · GM · contact PI
Epigenetic control of virulence in a fungal meningitis pathogen$384,572
R01 · FY2019 · AI · contact PI
Cryptococcus knockout and tag resource$632,795
R01 · FY2018 · AI · contact PI
Epigenetic control of virulence in a fungal meningitis pathogen$385,128
R01 · FY2018 · AI · contact PI
Cryptococcus knockout and tag resource$632,795
R01 · FY2017 · AI · contact PI
Epigenetic control of virulence in a fungal meningitis pathogen$385,657
R01 · FY2017 · AI · contact PI
Peptide-based signaling and virulence in Cryptococcus neoformans$376,607
R56 · FY2017 · AI · contact PI
Mechanism of Gene Silencing$352,042
R01 · FY2017 · GM · contact PI
Cryptococcus neoformans Gene Knockout Resource$518,524
R01 · FY2016 · AI · contact PI
Chemical-genetic functional annotation of the genome of a meningitis pathogen$449,515
R01 · FY2016 · AI · contact PI
Regulation of Virulence of Cryptococcus neoformans$386,250
R01 · FY2016 · AI · contact PI
Epigenetic control of virulence in a fungal meningitis pathogen$386,162
R01 · FY2016 · AI · contact PI
Mechanism of Gene Silencing$352,042
R01 · FY2016 · GM · contact PI
Cryptococcus neoformans Gene Knockout Resource$661,348
R01 · FY2015 · AI · contact PI
Chemical-genetic functional annotation of the genome of a meningitis pathogen$449,515
R01 · FY2015 · AI · contact PI
Epigenetic control of virulence in a fungal meningitis pathogen$386,642
R01 · FY2015 · AI · contact PI
Regulation of Virulence of Cryptococcus neoformans$386,250
R01 · FY2015 · AI · contact PI
Mechanism of Gene Silencing$352,042
R01 · FY2015 · GM · contact PI
Cryptococcus neoformans Gene Knockout Resource$661,348
R01 · FY2014 · AI · contact PI
Chemical-genetic functional annotation of the genome of a meningitis pathogen$449,515
R01 · FY2014 · AI · contact PI
Regulation of Virulence of Cryptococcus neoformans$386,250
R01 · FY2014 · AI · contact PI
Mechanism of Gene Silencing$350,960
R01 · FY2014 · GM · contact PI
Cryptococcus neoformans Gene Knockout Resource$623,309
R01 · FY2013 · AI · contact PI
Chemical-genetic functional annotation of the genome of a meningitis pathogen$422,544
R01 · FY2013 · AI · contact PI
Regulation of Virulence of Cryptococcus neoformans$363,075
R01 · FY2013 · AI · contact PI
Mechanisms of Gene Silencing$329,057
R01 · FY2013 · GM · contact PI
Cryptococcus neoformans Gene Knockout Resource$638,657
R01 · FY2012 · AI · contact PI
Chemical-genetic functional annotation of the genome of a meningitis pathogen$449,515
R01 · FY2012 · AI · contact PI
Regulation of Virulence of Cryptococcus neoformans$386,250
R01 · FY2012 · AI · contact PI
Mechanisms of Gene Silencing$340,268
R01 · FY2012 · GM · contact PI
Systems Biology of Molecular Noise in Yeast$283,279
R01 · FY2012 · GM
Mechanisms of Gene Silencing$308,823
R01 · FY2011 · GM · contact PI
Systems Biology of Molecular Noise in Yeast$283,279
R01 · FY2011 · GM
RNA INTERFERENCE IN THE HUMAN FUNGAL PATHOGEN CRYPTOCOCCUS NEOFORMANS$22,738
P41 · FY2011 · RR · contact PI
AN RNA-BINDING PROTEIN ASSOCIATES WITH HETEROCHROMATIC RNAS TO TRIGGER SILENCING$12,768
P41 · FY2011 · RR · contact PI
Mechanisms of Gene Silencing$342,660
R01 · FY2010 · GM · contact PI
Systems Biology of Molecular Noise in Yeast$286,140
R01 · FY2010 · GM
Mechanisms of Signal Transduction Specificity in Yeast$238,582
R01 · FY2010 · GM · contact PI
CRYPTOCOCCUS NEOFORMANS SECRETED PROTEINS$7,064
P41 · FY2010 · RR · contact PI
UNDERSTANDING THE FIDELITY OF MAP KINASE SIGNALING$2,425
P41 · FY2010 · RR · contact PI
Systematic Genetic Analysis of Fungal Virulence$347,914
R01 · FY2009 · AI · contact PI
Systems Biology of Molecular Noise in Yeast$289,030
R01 · FY2009 · GM
Mechanisms of Signal Transduction Specificity in Yeast$240,992
R01 · FY2009 · GM · contact PI
Mechanisms of Signal Transduction Specificity in Yeast$100,000
R01 · FY2009 · GM · contact PI
UNDERSTANDING THE FIDELITY OF MAP KINASE SIGNALING$3,309
P41 · FY2009 · RR · contact PI
STUDY OF THE ROLE OF ERS1 IN RNAI-DEPENDENT HETEROCHROMATIC SILENCING IN SPOMBE$3,309
P41 · FY2009 · RR · contact PI
Systematic Genetic Analysis of Fungal Virulence$348,043
R01 · FY2008 · AI · contact PI
Epigenetic Regulation by Histone Substitution$264,876
R01 · FY2008 · GM · contact PI
Mechanisms of Signal Transduction Specificity in Yeast$240,744
R01 · FY2008 · GM · contact PI
UNDERSTANDING THE FIDELITY OF MAP KINASE SIGNALING$819
P41 · FY2008 · RR · contact PI
Systematic Genetic Analysis of Fungal Virulence$354,910
R01 · FY2007 · AI · contact PI
Epigenetic Regulation by Histone Substitution$283,453
R01 · FY2007 · GM · contact PI
Mechanisms of Signal Transduction Specificity in Yeast$240,001
R01 · FY2007 · GM · contact PI
UNDERSTANDING THE FIDELITY OF MAP KINASE SIGNALING$6,224
P41 · FY2007 · RR · contact PI
HISTONE H3 & H33 ARE DISPENSABLE FOR VIABILITY AND CLR4-DEPENDENT TRANSPOSITION$6,224
P41 · FY2007 · RR · contact PI
Systematic Genetic Analysis of Fungal Virulence$365,637
R01 · FY2006 · AI · contact PI
Epigenetic Regulation by Histone Substitution$273,474
R01 · FY2006 · GM · contact PI
Epigenetic Regulation by Histone Substitution$34,922
R01 · FY2006 · GM · contact PI
PHEROMONE-DEPENDENT DESTRUCTION OF THE TEC1 TRANSCRIPTION FACTOR IS REQUIRED FO$2,859
P41 · FY2006 · RR · contact PI
Systematic Genetic Analysis of Fungal Virulence$318,377
R01 · FY2005 · AI
Epigenetic Regulation by Histone Substitution$280,393
R01 · FY2005 · GM
Mechanisms of Signal Transduction Specificity in Yeast$224,224
R01 · FY2005 · GM
PHEROMONE-DEPENDENT DESTRUCTION OF THE TEC1 TRANSCRIPTION FACTOR IS REQUIRED FO$5,655
P41 · FY2005 · RR
Mechanisms of Signal Transduction Specificity in Yeast$226,419
R01 · FY2004 · GM
Mechanisms of Signal Transduction Specificity in Yeast$224,224
R01 · FY2003 · GM
Mechanisms of Signal Transduction Specificity in Yeast$221,664
R01 · FY2002 · GM
Mechanisms of Signal Transduction Specificity in Yeast$225,687
R01 · FY2001 · GM