← Leaderboards
Brian K. Shoichet
Univ Of North Carolina Chapel Hill
$34,511,792
Attributed
$47,982,418
Total exposure
37
Grants
30
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $5M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$47,982,418 · 37
By mechanism
R01$23,343,307 · 6
U24$14,263,452 · 1
R35$7,719,679 · 1
U01$1,416,612 · 1
P01$833,996 · 1
P41$380,372 · 26
Top collaborators
- Bryan L Roth24 shared
- John J. Irwin11 shared
Most similar at Univ Of North Carolina Chapel Hill
Same institution · by research overlap
- Bryan L Roth$59,246,636
- Moriah R Beck$1,210,520
- Kevin C Slep$2,542,010
- Mrinalini Ramanan$71,199
- Amy Elizabeth Byrnes$64,718
Others in their field
Top investigators on “Structure”
- David Heimbrook · Leidos Biomedical Research, Inc.$475,333,582
- Barton F Haynes · Duke University$444,977,767
- Lawrence Corey · Fred Hutchinson Cancer Center$334,646,086
- Gary D Acton · University Of California-Davis$320,373,312
- Mitchell J Malone · Texas A&M Research Foundation$320,373,312
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$315,257,203
Research focus
StructureLigandsDockingBasePharmaceutical PreparationsProteinsReceptorReagentGrantLibrariesMolecularDrug DiscoveryBiologicalBiologySiteFundingDatabasesG-Protein-Coupled ReceptorsResearch PersonnelComplexCommunitiesSignal TransductionResourcesInhibitor/Antagonist
Grant awards (124)
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$798,338
R35 · FY2025 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$599,826
R01 · FY2025 · MH
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$563,447
R01 · FY2025 · DA
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$798,338
R35 · FY2024 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$605,561
R01 · FY2024 · MH
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$563,447
R01 · FY2024 · DA
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$798,338
R35 · FY2023 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$611,184
R01 · FY2023 · MH
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$566,946
R01 · FY2023 · DA
Illuminating the Druggable GPCR-ome$2,239,055
U24 · FY2022 · DK
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$798,338
R35 · FY2022 · GM · contact PI
Illuminating the Druggable GPCR-ome$749,510
U24 · FY2022 · DK
Molecular Details of Psychoactive Drug Actions$629,016
R01 · FY2022 · MH
STRUCTURE AND FUNCTION OF MRG-FAMILY RECEPTORS$582,640
R01 · FY2022 · DA
Illuminating the Druggable GPCR-ome$2,241,036
U24 · FY2021 · DK
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$1,034,213
R35 · FY2021 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2021 · MH
Illuminating the Druggable GPCR-ome$2,242,958
U24 · FY2020 · DK
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$1,034,213
R35 · FY2020 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2020 · MH
Illuminating the Druggable GPCR-ome$2,243,887
U24 · FY2019 · DK
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$880,204
R35 · FY2019 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2019 · MH
A Web-Based Automatic Virtual Screening System$348,700
R01 · FY2019 · GM
Illuminating the Druggable GPCR-ome$2,245,696
U24 · FY2018 · DK
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$866,203
R35 · FY2018 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$602,028
R01 · FY2018 · MH
A Web-Based Automatic Virtual Screening System$348,700
R01 · FY2018 · GM
Illuminating the druggable GPCR-ome$2,301,310
U24 · FY2017 · DK
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism$711,494
R35 · FY2017 · GM · contact PI
Molecular Details of Psychoactive Drug Actions$646,715
R01 · FY2017 · MH
A Web-Based Automatic Virtual Screening System$348,700
R01 · FY2017 · GM · contact PI
Design and Experimental Testing of New Docking Methods$337,420
R01 · FY2017 · GM · contact PI
Scalable technologies for illuminating the druggable GPCR-ome$396,932
U01 · FY2016 · MH
A Web-Based Automatic Virtual Screening System$348,700
R01 · FY2016 · GM · contact PI
Design and Experimental Testing of New Docking Methods$337,420
R01 · FY2016 · GM · contact PI
A Specific Mechanism for non-specific inhibition$317,706
R01 · FY2016 · GM · contact PI
Scalable technologies for illuminating the druggable GPCR-ome$396,932
U01 · FY2015 · MH
Design and Experimental Testing of New Docking Methods$336,799
R01 · FY2015 · GM · contact PI
A Web-Based Automatic Virtual Screening System$334,641
R01 · FY2015 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$306,421
R01 · FY2015 · GM · contact PI
Scalable technologies for illuminating the druggable GPCR-ome$213,200
U01 · FY2015 · MH
Scalable technologies for illuminating the druggable GPCR-ome$409,548
U01 · FY2014 · MH
A Web-Based Automatic Virtual Screening System$333,674
R01 · FY2014 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$320,181
R01 · FY2014 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$1
R01 · FY2014 · GM · contact PI
Design and Experimental Testing of New Docking Methods$300,525
R01 · FY2013 · GM · contact PI
Structure, Function and Inhibition of Beta-Lactamases$272,062
R01 · FY2013 · GM · contact PI
A Web-Based Automatic Virtual Screening System$228,081
R01 · FY2013 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$216,257
R01 · FY2013 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$1
R01 · FY2013 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$317,303
R01 · FY2012 · GM · contact PI
Design and Experimental Testing of New Docking Methods$312,445
R01 · FY2012 · GM · contact PI
A Web-Based Automatic Virtual Screening System$303,343
R01 · FY2012 · GM · contact PI
Structure, Function and Inhibition of Beta-Lactamases$281,930
R01 · FY2012 · GM · contact PI
Design and Experimental Testing of New Docking Methods$313,467
R01 · FY2011 · GM · contact PI
A Web-Based Automatic Virtual Screening System$303,343
R01 · FY2011 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$284,859
R01 · FY2011 · GM · contact PI
Structure, Function and Inhibition of Beta-Lactamases$281,930
R01 · FY2011 · GM · contact PI
LINGANDS BINDING TO PRP$277,936
P01 · FY2011 · AG · contact PI
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$16,768
P41 · FY2011 · RR · contact PI
DESIGN AND TESTING OF DOCKING ALGORITHMS$16,768
P41 · FY2011 · RR · contact PI
ANNOTATION OF PROTEIN FUNCTION BY LIGAND DESCRIPTORS$10,164
P41 · FY2011 · RR · contact PI
MECHANISM OF PROMISCUOUS INHIBITION BY SMALL MOLECULE AGGREGATION$66
P41 · FY2011 · RR · contact PI
Design and Experimental Testing of New Docking Methods$317,605
R01 · FY2010 · GM · contact PI
A Web-Based Automatic Virtual Screening System$306,407
R01 · FY2010 · GM · contact PI
Structure, Function and Inhibition of Beta-Lactamases$298,403
R01 · FY2010 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$287,736
R01 · FY2010 · GM · contact PI
LINGANDS BINDING TO PRP$280,743
P01 · FY2010 · AG · contact PI
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$17,804
P41 · FY2010 · RR · contact PI
DESIGN AND TESTING OF DOCKING ALGORITHMS$17,804
P41 · FY2010 · RR · contact PI
ANNOTATION OF PROTEIN FUNCTION BY LIGAND DESCRIPTORS$7,145
P41 · FY2010 · RR · contact PI
MECHANISM OF PROMISCUOUS INHIBITION BY SMALL MOLECULE AGGREGATION$1,766
P41 · FY2010 · RR · contact PI
A Specific Mechanism for Non-Specific Inhibition$290,642
R01 · FY2009 · GM · contact PI
A Web-Based Automatic Virtual Screening System$280,006
R01 · FY2009 · GM · contact PI
LINGANDS BINDING TO PRP$275,317
P01 · FY2009 · AG · contact PI
A Specific Mechanism for Non-Specific Inhibition$154,559
R01 · FY2009 · GM · contact PI
DESIGN AND TESTING OF DOCKING ALGORITHMS$23,696
P41 · FY2009 · RR · contact PI
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$23,696
P41 · FY2009 · RR · contact PI
ANNOTATION OF PROTEIN FUNCTION BY LIGAND DESCRIPTORS$8,757
P41 · FY2009 · RR · contact PI
MECHANISM OF PROMISCUOUS INHIBITION BY SMALL MOLECULE AGGREGATION$4,664
P41 · FY2009 · RR · contact PI
A Specific Mechanism for Non-Specific Inhibition$290,496
R01 · FY2008 · GM · contact PI
Design and Experimental Testing of New Docking Methods$269,590
R01 · FY2008 · GM · contact PI
Structure, Function and Inhibition of Beta-lactamases$208,692
R01 · FY2008 · GM · contact PI
A Web-Based Automatic Molecular Docking System$77,199
R01 · FY2008 · GM · contact PI
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$15,353
P41 · FY2008 · RR · contact PI
DESIGN AND TESTING OF DOCKING ALGORITHMS$15,353
P41 · FY2008 · RR · contact PI
MECHANISM OF PROMISCUOUS INHIBITION BY SMALL MOLECULE AGGREGATION$8,443
P41 · FY2008 · RR · contact PI
ANNOTATION OF PROTEIN FUNCTION BY LIGAND DESCRIPTORS$5,792
P41 · FY2008 · RR · contact PI
Design and Experimental Testing of New Docking Methods$269,590
R01 · FY2007 · GM · contact PI
A Web-Based Automatic Molecular Docking System$254,377
R01 · FY2007 · GM · contact PI
Structure, Function and Inhibition of Beta-lactamases$208,692
R01 · FY2007 · GM · contact PI
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$29,093
P41 · FY2007 · RR · contact PI
DESIGN AND TESTING OF DOCKING ALGORITHMS$29,093
P41 · FY2007 · RR · contact PI
Promiscuous and Specific Inhibitors of Cruzain$25,000
R03 · FY2007 · DA · contact PI
ANNOTATION OF PROTEIN FUNCTION BY LIGAND DESCRIPTORS$8,926
P41 · FY2007 · RR · contact PI
MECHANISM OF PROMISCUOUS INHIBITION BY SMALL MOLECULE AGGREGATION$134
P41 · FY2007 · RR · contact PI
Design and Experimental Testing of New Docking Methods$277,642
R01 · FY2006 · GM · contact PI
A Specific Mechanism for Non-Specific Inhibition$274,517
R01 · FY2006 · GM · contact PI
A Web-Based Automatic Molecular Docking System$261,975
R01 · FY2006 · GM · contact PI
Structure, Function and Inhibition of Beta-lactamases$214,925
R01 · FY2006 · GM · contact PI
A Web-Based Automatic Molecular Docking System$36,985
R01 · FY2006 · GM · contact PI
DESIGN AND TESTING OF DOCKING ALGORITHMS$22,067
P41 · FY2006 · RR · contact PI
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$22,067
P41 · FY2006 · RR · contact PI
ANNOTATION OF PROTEIN FUNCTION BY LIGAND DESCRIPTORS$7,655
P41 · FY2006 · RR · contact PI
Design and Experimental Testing of New Docking Methods$284,324
R01 · FY2005 · GM
A Specific Mechanism for Non-Specific Inhibition$281,123
R01 · FY2005 · GM
A Web-Based Automatic Molecular Docking System$268,280
R01 · FY2005 · GM
Structure, Function and Inhibition of Beta-lactamases$230,397
R01 · FY2005 · GM
A WEB-BASED AUTOMATIC MOLECULAR DOCKING SYSTEM$22,570
P41 · FY2005 · RR
DESIGN AND TESTING OF DOCKING ALGORITHMS$22,570
P41 · FY2005 · RR
A Specific Mechanism for Non-Specific Inhibition$281,123
R01 · FY2004 · GM
A Web-Based Automatic Molecular Docking System$268,280
R01 · FY2004 · GM
Structure,Function, and Inhibition of Beta-lactamases$215,465
R01 · FY2004 · GM
DESIGN AND EXPERIMENTAL TESTING OF NEW DOCKING METHODS$86,379
R01 · FY2004 · GM
DESIGN AND TESTING OF DOCKING ALGORITHMS$22,158
P41 · FY2004 · RR
DESIGN AND EXPERIMENTAL TESTING OF NEW DOCKING METHODS$258,304
R01 · FY2003 · GM
Structure,Function, and Inhibition of Beta-lactamases$228,340
R01 · FY2003 · GM
Structure,Function, and Inhibition of Beta-lactamases$210,095
R01 · FY2002 · GM
DESIGN AND EXPERIMENTAL TESTING OF NEW DOCKING METHODS$144,887
R01 · FY2002 · GM
DESIGN AND EXPERIMENTAL TESTING OF NEW DOCKING METHODS$103,382
R01 · FY2002 · GM
DESIGN AND EXPERIMENTAL TESTING OF NEW DOCKING METHODS$239,569
R01 · FY2001 · GM
Structure,Function, and Inhibition of Beta-lactamases$219,142
R01 · FY2001 · GM
DESIGN AND EXPERIMENTAL TESTING OF NEW DOCKING METHODS$232,676
R01 · FY2000 · GM