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16,179 grants matching “malaria”
Center for Children's Environmental Health Research
$690,271Brenda Eskenazi · University Of California Berkeley · P01 · FY2012 · ES
MALARIA CONTROL BY GENETIC MANIPULATION OF VECTORS
$690,210University Of Notre Dame · P01 · FY2002 · AI
Understanding, tracking and eliminating malaria transmission in the Asia - Pacific Region
$690,181Ivo J Mueller · Institut Pasteur · U19 · FY2017 · AI
Protein Synthesis And Developmental Transitions In Plasmodium
$689,871Thomas McCutchan · National Institute Of Allergy And Infectious Diseases · Z01 · FY2008 · AI
Novel Plasmodial Surface Anion Channel Inhibitors as Antimalarial Drugs
$689,746Michelle M. Butler · Microbiotix, Inc · R44 · FY2016 · AI
Structure and function of the Plasmodium myosin XIV-actin glideosome.
$689,630Kathleen M Trybus · University Of Vermont & St Agric College · R01 · FY2022 · AI
An.gambiae immune signaling gene SNPs and natural P. falciparum infection
$689,552Shirley Luckhart · University Of California At Davis · R01 · FY2010 · AI
Novel Combination Adjuvant for Eliciting Systemic and Mucosal CD8 T Cell Memory
$689,029Marulasiddappa Suresh · University Of Wisconsin-Madison · U01 · FY2020 · AI
Malaria Epidemiology and Vector Biology of Anopheles stephensi across Rural and Urban Landscapes in Ethiopia
$689,004Guiyun Yan · University Of California-Irvine · U19 · FY2025 · AI
Host Immune Responses to Antigens of Malaria Parasites
$688,954Carole Long · National Institute Of Allergy And Infectious Diseases · ZIA · FY2013 · AI
Chemogenomic Profiling of Plasmodium falciparum Drug Responses and Resistance
$688,697John Adams · University Of South Florida · R01 · FY2019 · AI
Development of endochin-like quinolones for babesiosis therapy
$688,626Choukri Ben Mamoun · Yale University · R01 · FY2017 · AI
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile Immunity
$688,369David R. Milich · Vaccine Research Institute Of San Diego · R01 · FY2024 · AI
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile Immunity
$688,369David R. Milich · Vaccine Research Institute Of San Diego · R01 · FY2023 · AI
Epitope-Based CSP Vaccines Optimized to Achieve Long-Term Sterile Immunity
$688,369David R. Milich · Vaccine Research Institute Of San Diego · R01 · FY2025 · AI
COVID Transmission and Morbidity in Malawi (COVID-TMM)
$688,360Clarissa Valim · Boston University Medical Campus · R01 · FY2024 · AI
Center for Humanized Mice
$688,191Larisa Y Poluektova · University Of Nebraska Medical Center · R24 · FY2014 · OD
Multi-Omics Characterization of Plasmodium Vivax Hypnozoites
$688,160David Serre · University Of Maryland Baltimore · R01 · FY2025 · AI
Optimization of antimalarials targeting multiple life stages of the parasite
$688,004Paul R Carlier · University Of Illinois At Chicago · R01 · FY2025 · AI
A Systems Biology Approach to Malaria Immunity
$687,931Kim C Williamson · Henry M. Jackson Fdn For The Adv Mil/Med · U01 · FY2019 · AI
The Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
$687,523Charles W. Flexner · Johns Hopkins University · R24 · FY2022 · AI
Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasites
$687,521Jeffrey D Dvorin · Boston Children'S Hospital · R01 · FY2025 · AI
RESEARCHERS AT THE UNIVERSITY OF ALABAMA IN HUNTSVILLE (UAH) IN COLLABORATION WITH THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) AND THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) PROPOSE TO IMPROVE MALARIA CONTROL DECISION MAKING IN SUB-SAHARAN AFRICA BY DEVELOPING AND DEPLOYING A TECHNOLOGY FOR INCORPORATING THE LATEST NASA EARTH OBSERVATIONS FOR SURFACE TEMPERATURES PRECIPITATION AND VEGETATION HEALTH INTO A WIDELY USED HEALTH MANAGEMENT PLATFORM TITLED DISTRICT HEALTH INFORMATION SOFTWARE 2 (DHIS2). DHIS2 IS THE PREFERRED HEALTH MANAGEMENT INFORMATION SYSTEM IN 60 COUNTRIES ACROSS FOUR CONTINENTS WORLDWIDE INCLUDING ALL SUB-SAHARAN AFRICAN COUNTRIES WITH WHOM CDC WORKS. DHIS2 IS USED BY CDC THE EUROPEAN UNION (EU) AND OTHER HEALTH FACILITIES AND GOVERNMENT ORGANIZATIONS TO MONITOR DISEASES PROVIDE VITAL HEALTH DATA AND SUPPORT DISEASE-CONTROL DECISION MAKING. MALARIA HAS BEEN SELECTED FOR THE CASE STUDY BECAUSE OF THE WELL-ESTABLISHED IMPACTS OF ENVIRONMENTAL FACTORS ON TRANSMISSION OF THE DISEASE. THIS PROPOSAL IS BASED ON THE HYPOTHESIS THAT INTEGRATION OF DISEASE INFORMATION WITH ENVIRONMENTAL DATA CAN PROVIDE DISEASE CONTROL DECISION MAKERS WITH THE INTEGRATED ACCURATE AND UP-TO-DATE SITUATIONAL VIEW NEEDED TO OPTIMIZE INTERVENTIONS. SUCCESSFUL FUSION OF EARTH OBSERVATION DATA WITH A HEALTH MONITORING APPLICATION WILL BE APPLICABLE TO OTHER NASA DATA PRODUCTS AND OTHER DISEASES MONITORED THROUGH DHIS2. THIS PROPOSAL BRINGS TOGETHER A STRONG TEAM OF EXPERTS WITH A HISTORY OF RESEARCH IN ATMOSPHERIC SCIENCE EARTH SCIENCE GEOSPATIAL TECHNOLOGY REMOTE SENSING DISEASE MONITORING AS WELL AS A PROVEN TRACK RECORD OF PREVIOUS COLLABORATIONS: PI DR. JOHN BECK (UAH) GEOSPATIAL TECHNOLOGY LEAD; CO-I DR. JOHN PAINTER (CDC) MALARIA RESEARCHER AND DHIS2 USER; CO-I DR. UDAYSANKAR NAIR (UAH) VEGETATION HEALTH REMOTE SENSING ATMOSPHERIC SCIENCE RESEARCHER; MR. TODD BERENDES (UAH) SOFTWARE DEVELOPMENT AND PRECIPITATION RESEARCHER; AND DR. DALE QUATTROCHI (NASA) REMOTE SENSING AND TEMPERATURE RESEARCHER. WE WILL ALSO LEVERAGE EXPERT KNOWLEDGE BY COLLABORATING WITH DR. WALT PETERSEN (NASA) GLOBAL PRECIPITATION MEASUREMENTS (GPM) DEPUTY PROGRAM SCIENTIST. THE OBJECTIVES OF THIS APPLIED RESEARCH PROJECT WILL BE TO DEMONSTRATE (1) ENHANCED HEALTH DECISION MAKING FOR MALARIA CONTROL BY EMPLOYING THE LATEST RELEVANT NASA EARTH OBSERVATIONS INTO AN EXISTING DECISION-MAKING ACTIVITY AND (2) DEVELOPING AND DEPLOYING TECHNOLOGY SOLUTIONS THAT WILL PROVIDE A PATH TO LONG-TERM SUSTAINABILITY FOR THE USE OF NASA EARTH OBSERVATIONS TO END-USER HEALTH DECISION MAKERS. THE UAH AND NASA TEAM MEMBERS PROVIDE STRONG EARTH SCIENCE DATA AND TECHNOLOGY EXPERIENCE TO THE DEVELOPMENT OF SOLUTIONS FOR INTEGRATING STATE-OF-THE-ART EARTH OBSERVATIONS INTO AN EXISTING BROADLY USED DECISION SUPPORT PLATFORM. THE CDC TEAM BRINGS EXPERTISE IN MALARIA EPIDEMIOLOGY AND ESTABLISHED COLLABORATIONS WITH MANY OF THE SUB-SAHARAN AFRICAN COUNTRIES THAT WILL BE CONSIDERED FOR TEAMING AS END-USER PARTICIPANTS. TRAVEL TO PARTICIPATING COUNTRIES FOR CLOSE INTERACTIONS WITH THEIR MINISTRIES OF HEALTH WILL BE CRUCIAL FOR TEAM-BUILDING DEPLOYMENT AND TESTING OF THE TECHNOLOGIES AND DATA AS WELL AS LONG-TERM SUSTAINABILITY OF THE RESULTING IMPROVED DECISION-MAKING CAPACITY.
$687,440The University Of Alabama In Huntsville · · FY2020 · National Aeronautics and Space Administration
Development of Pre-Erythrocytic Malaria Vaccines
$686,983Robert A Seder · National Institute Of Allergy And Infectious Diseases · ZIA · FY2010 · AI
Protein glycosylation and trafficking in Plasmodium falciparum
$686,914Vasant Muralidharan · University Of Georgia · R01 · FY2025 · AI