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30,917 grants matching tumor microenvironment

REWIRING SUPPRESSIVE TUMOR MICROENVIRONMENT SIGNALS FOR IMMUNE ACTIVATION USING T CELLS ENGINEERED WITH SYNTHETIC PROMOTERS

$747,221
Massachusetts Institute Of Technology · · FY2021 · Defense Health Agency

Mechanisms of pathogenesis in patient derived organoid models of prostate cancer

$747,170
Kathleen Kelly · Division Of Basic Sciences - Nci · ZIA · FY2019 · CA

Biological Comparisons Among Three Derivative Models of Glioma Patient Cancers Under Microenvironmental Stress

$746,835
Christopher D Willey · University Of Alabama At Birmingham · U01 · FY2019 · CA

Using implantable microdevices for deep phenotyping of multiple drug responses in brain tumor patients

$746,821
Oliver Jonas · Brigham And Women'S Hospital · R01 · FY2023 · CA

Targeting tumor and T cell DNA methylomes to improve CAR T cell therapies for diffuse midline glioma

$746,809
Stephen C Mack · St. Jude Children'S Research Hospital · U01 · FY2024 · CA

Microenvironmental regulation of glioblastoma radiosensitivity

$746,706
Philip Tofilon · Division Of Basic Sciences - Nci · ZIA · FY2014 · CA

An organotypic model recapitulating colon cancer microenvironment and metastasis

$746,690
Emina Hui-Na Huang · Cleveland Clinic Lerner Com-Cwru · U01 · FY2019 · CA

Preclinical drug development in pancreas cancer

$746,546
Udo Rudloff · Division Of Basic Sciences - Nci · ZIA · FY2010 · CA

Vevo 3100 ultrasound scanner and PV loop system

$746,509
Flemming Forsberg · Thomas Jefferson University · S10 · FY2021 · OD

Clinical Protocol and Data Management

$746,042
Scott Michael Schuetze · University Of Michigan At Ann Arbor · P30 · FY2024 · CA

The Pacific Northwest Prostate Cancer SPORE

$745,961
Peter S Nelson · Fred Hutchinson Cancer Research Center · P50 · FY2016 · CA

EBNA1 Inhibitor for Treatment of EBV-positive DLBCL

$745,842
Paul M. Lieberman · Wistar Institute · R01 · FY2023 · CA

Targeting the immunosuppressive tumor microenvironment to enhance efficacy of radiotherapy and immuno-radiotherapy for oral cancer

$745,334
Andrew Sikora · University Of Tx Md Anderson Can Ctr · U01 · FY2021 · DE

Understanding omega-3 and 6 fatty acid dependent regulation of inflammatory signals in pancreatic cancer

$745,320
Susan M Kaech · Salk Institute For Biological Studies · U01 · FY2025 · CA

Harnessing double stranded-RNA (dsRNA)-response and anti-tumor effect in PRC2-inactivated cancer

$745,005
Ping Chi · Sloan-Kettering Inst Can Research · R01 · FY2023 · CA

Pathways and critical regulators of early beta-cell dysfunction in type 1 diabetes

$744,819
Wei-Jun Qian · Battelle Pacific Northwest Laboratories · R01 · FY2020 · DK

Synthetic circuit technologies for precision control and signal processing in mammalian cells

$744,685
Ahmad Samir Khalil · Boston University (Charles River Campus) · R01 · FY2025 · EB

Tumor stem cells and metastatic outcomes in mouse models of prostate cancer

$744,376
Kathleen Kelly · Division Of Basic Sciences - Nci · ZIA · FY2009 · CA

Nitric Oxide as a Modifier of Oxidative Stress

$743,717
David Wink · Division Of Clinical Sciences - Nci · ZIA · FY2025 · CA

Nano-Therapeutic Approaches for Oncogenic Herpesvirus-Mediated Malignancies

$743,574
Yoshihiro Izumiya · University Of California At Davis · R01 · FY2020 · CA

Cell density effects on therapeutic sensitivity

$743,010
Jayne Stommel · Division Of Basic Sciences - Nci · ZIA · FY2014 · CA

Model-based Prediction of Redox-Modulated Responses to Cancer Treatments

$742,970
Melissa Lambeth Kemp · Georgia Institute Of Technology · U01 · FY2020 · CA

AGR2-superantigen vaccine conjugate for the treatment of pancreaticductal adenocarcinoma

$742,887
Reeder McNeil Robinson · Leukogene Therapeutics, Inc. · R44 · FY2024 · CA

AGR2-superantigen vaccine conjugate for the treatment of pancreaticductal adenocarcinoma

$742,887
Reeder McNeil Robinson · Leukogene Therapeutics, Inc. · R44 · FY2025 · CA

REPROGRAMMING THE TUMOR MICROENVIRONMENT TO IMPROVE HEARING AND TREATMENT EFFICACY IN NF2 VESTIBULAR SCHWANNOMA.

$742,819
The General Hospital Corporation · · FY2020 · Defense Health Agency