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10,766 grants matching checkpoint inhibitor

Exploring the Function of MHC-II/Lag3 Axis in Brain Metastasis to Develop Novel Therapeutic Strategies

$526,134
Dihua Yu · University Of Tx Md Anderson Can Ctr · R01 · FY2022 · CA

Exploring the Function of MHC-II/Lag3 Axis in Brain Metastasis to Develop Novel Therapeutic Strategies

$526,134
Dihua Yu · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · CA

Macrophages as modulators of T cell function and therapeutic response in clear cell renal cell carcinoma

$526,128
Abraham Ari Hakimi · Sloan-Kettering Inst Can Research · R01 · FY2021 · CA

Cyclin C-CDK8/19 kinases in development and in cancer

$525,969
Piotr Sicinski · Dana-Farber Cancer Inst · R01 · FY2025 · CA

Cyclin C-CDK8/19 kinases in development and in cancer

$525,969
Piotr Sicinski · Dana-Farber Cancer Inst · R01 · FY2022 · CA

Development of a novel biodegradable inorganic nanoparticle therapeutic for cancer

$525,898
Jin Xie · University Of Georgia · R01 · FY2023 · CA

Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma

$525,822
J. Silvio Gutkind · University Of California, San Diego · R01 · FY2023 · CA

Analysis of the Functional Roles of a Novel G-alpha Nucleotide Cycle

$525,658
John H Kehrl · National Institute Of Allergy And Infectious Diseases · ZIA · FY2011 · AI

Modulation of the tumor microenvironment with probiotic therapies

$525,502
Tal Danino · Columbia Univ New York Morningside · R01 · FY2024 · CA

Effective combination therapy for MTAP-deficient bladder carcinoma by targeting metabolic vulnerability and modulating tumor immune microenvironment

$525,061
Jianjun Gao · University Of Tx Md Anderson Can Ctr · R01 · FY2023 · CA

In vivo imaging of mitochondria structure and function in therapy resistant lung tumors

$524,804
David B Shackelford · University Of California Los Angeles · R01 · FY2023 · CA

Dual-specificity phosphatase action in muscle disease

$524,744
Anton M Bennett · Yale University · R01 · FY2022 · AR

Targeting HER2-low breast cancer with 17p loss

$524,740
Xiongbin Lu · Indiana University Indianapolis · R01 · FY2023 · CA

Targeting HER2-low breast cancer with 17p loss

$524,740
Xiongbin Lu · Indiana University Indianapolis · R01 · FY2022 · CA

Novel roles of PCSK9 in regulating the tumor immune microenvironment during radiotherapy

$524,375
Yunyan Jennifer Jennifer Zhang · Duke University · R01 · FY2023 · CA

Precision targeting of T cell cytotoxicity with PET

$524,205
Michael John Evans · University Of California, San Francisco · R01 · FY2021 · CA

Role of meningeal lymphatic vasculature in neuroimmune communication development

$524,089
Jean-Leon Thomas · Yale University · R01 · FY2023 · NS

UCSF Project 1

$524,054
Trever G Bivona · University Of California, San Francisco · U54 · FY2021 · CA

Plasmonic nanoparticle-mediated immunotherapy to treat metastatic cancer

$524,053
Tuan Vo-Dinh · Duke University · R01 · FY2021 · EB

Targeting the cGAS/STING Pathway to Overcome Resistance to Immune Checkpoint Inhibitors in PTEN-deficient Prostate Cancer

$523,982
Akash Patnaik · University Of Chicago · R01 · FY2023 · CA

Caspases in Inflammatory Cell Death Networks

$523,976
Guy S Salvesen · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2020 · GM

Caspases in Inflammatory Cell Death Networks

$523,976
Guy S Salvesen · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2019 · GM

POLQ Synthetic Lethality in HR-Deficient Pancreatic Adenocarcinoma

$523,841
Diane M Simeone · University Of California, San Diego · R01 · FY2024 · CA

Development of a RUVBL1/2 Inhibitor as a Radiosensitizer and Immune Stimulator for NSCLC

$523,830
Ralf Kittler · Ut Southwestern Medical Center · R01 · FY2024 · CA

Mechanism of LSD1 Function and Its Therapeutic Application for Progressive Oral Malignancy

$523,816
Manish Bais · Boston University Medical Campus · R01 · FY2024 · DE