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10,766 grants matching checkpoint inhibitor

Nanocage-based systemic delivery of TGFβ trap for immunomodulation of brain neoplasms

$505,850
Jung Soo Suk · Johns Hopkins University · R01 · FY2023 · NS

Dissecting the NRG4 hormonal checkpoint in metabolic liver disease

$505,838
Jiandie D Lin · University Of Michigan At Ann Arbor · R01 · FY2020 · DK

GENOTOXIC RESPONSES

$505,837
Trey Ideker · University Of California, San Diego · P50 · FY2013 · GM

TIGIT in acute kidney injury and repair

$505,269
Sanjeev Noel · Johns Hopkins University · R01 · FY2023 · DK

Exploring novel therapeutic strategies for combinatory therapy to treat renal clear cell carcinomas

$505,159
Weizhou Zhang · University Of Florida · R01 · FY2023 · CA

Project 2 - Preclinical studies: Overcoming tumor heterogeneity

$505,053
Steven Mark Albelda · University Of Pennsylvania · P01 · FY2022 · CA

An Environmental Chemical Receptor, the AhR, as a Mediator of Multiple Immune Checkpoints in Oral Cancer

$504,865
David H Sherr · Boston University Medical Campus · R01 · FY2023 · ES

Project 2 - Preclinical studies: Overcoming tumor heterogeneity

$504,690
Steven Mark Albelda · University Of Pennsylvania · P01 · FY2019 · CA

Inhibiting Multi-Functional ALDOA for Cancer Therapy

$504,587
Garth Powis · Phusis Therapeutics, Inc. · R01 · FY2021 · CA

Role of Meis1 in Regulation of Cardiomyocyte Proliferation

$504,559
Hesham Sadek · Ut Southwestern Medical Center · R01 · FY2015 · HL

Nanoscale Metal-Organic Frameworks Enable Radiotherapy-Radiodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Generate Tumor Vaccines and Potentiate Immunotherapy of Head and Neck Cancers

$504,359
Wenbin Lin · University Of Chicago · R01 · FY2021 · CA

Role of histotripsy synergized CD40 signaling in the re-engineering of cold tumors

$504,109
Ashish Ranjan · Ut Southwestern Medical Center · R01 · FY2025 · CA

Project 4: Translation and preclinical studies of a personalized pancreas cancer vaccine

$503,987
William E Gillanders · Washington University · P50 · FY2018 · CA

AHR-mediated immunosuppression in glioblastoma

$503,741
Francisco J. Quintana · Brigham And Women'S Hospital · R01 · FY2019 · ES

Mechanisms of Tumor Derived Neutrophil Induced Apoptosis in Lymphocytes

$503,575
A. McGarry Houghton · Fred Hutchinson Cancer Research Center · R01 · FY2018 · CA

Development of a novel biodegradable inorganic nanoparticle therapeutic for cancer

$503,511
Jin Xie · University Of Georgia · R01 · FY2024 · CA

“Pharmacologic targeting of NR4A1 and NR4A2 to activate glioblastoma treatment response”

$503,363
Robert C Rostomily · Methodist Hospital Research Institute · R01 · FY2023 · NS

Characterizing and Targeting BAX- and BAK-Dependent Cell Death in Cancer

$503,337
Emily H Cheng · Sloan-Kettering Inst Can Research · R01 · FY2023 · CA

Characterizing and Targeting BAX- and BAK-Dependent Cell Death in Cancer

$503,337
Emily H Cheng · Sloan-Kettering Inst Can Research · R01 · FY2022 · CA

Protein Kinase Signaling and Cell Cycle Control

$503,262
Michael B Yaffe · Massachusetts Institute Of Technology · R01 · FY2016 · ES

Protein Kinase Signaling and Cell Cycle Control

$503,262
Michael B Yaffe · Massachusetts Institute Of Technology · R01 · FY2013 · ES

Protein Kinase Signaling and Cell Cycle Control

$503,262
Michael B Yaffe · Massachusetts Institute Of Technology · R01 · FY2015 · ES

Protein Kinase Signaling and Cell Cycle Control

$503,262
Michael B Yaffe · Massachusetts Institute Of Technology · R01 · FY2017 · ES

Targeting posttranslational modifications of B7-H4 in carcinogenesis and therapy

$503,234
Yong Wan · Emory University · R01 · FY2025 · CA

Assessing the efficacy of a ROR1:PD-L1:CD2 multispecific T cell engager in ROR1-positive and -negative neuroblastoma models

$503,194
James M Olson · Seattle Children'S Hospital · R21 · FY2024 · CA