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10,766 grants matching checkpoint inhibitor

Head & Neck Cancer Neoantigen Characterization & Therapeutic Targeting

$485,385
Young J. Kim · Vanderbilt University Medical Center · R01 · FY2018 · DE

Advancing immunotherapy through cross species studies of immune cell responses and immune checkpoint inhibitor effects in dogs and humans with invasive urinary bladder cancer

$485,357
Deborah W Knapp · Purdue University · U01 · FY2024 · CA

Targeting Autophagy in Hereditary Breast Cancer

$485,161
Bing Xia · Rbhs -Cancer Institute Of New Jersey · R01 · FY2015 · CA

Immunogen design and testing

$485,034
Barton F Haynes · University Of Pennsylvania · P01 · FY2019 · AI

Mechanisms of PD-1 and Tim-3 crosstalk in tumor-infiltrating lymphocytes

$484,976
Robert L Ferris · University Of Pittsburgh At Pittsburgh · R01 · FY2019 · CA

Multiscale Computational Models Guided By Emerging Cellular Dynamics Quantification For Predicting Optimum Immune Checkpoint And Targeted Therapy Schedules

$484,762
Trachette Jackson · University Of Michigan At Ann Arbor · U01 · FY2023 · CA

Mechanistic analyses of a novel RNA polymerase I transcription checkpoint

$484,599
Marikki Laiho · Johns Hopkins University · R01 · FY2018 · GM

Combating Resistance of Pancreatic Cancer with a First-in-Class Dual Targeted PI3K/EGFR Inhibitor

$484,410
Judith S Leopold · University Of Michigan At Ann Arbor · R01 · FY2021 · CA

Combating Resistance of Pancreatic Cancer with a First-in-Class Dual Targeted PI3K/EGFR Inhibitor

$484,410
Judith S Leopold · University Of Michigan At Ann Arbor · R01 · FY2019 · CA

Combating Resistance of Pancreatic Cancer with a First-in-Class Dual Targeted PI3K/EGFR Inhibitor

$484,410
Judith S Leopold · University Of Michigan At Ann Arbor · R01 · FY2020 · CA

Targeting a Novel Signaling Nexus pACK/pCSK/pLCK in Immune Checkpoint Blockade (ICB)-Resistant Prostate Cancer

$484,365
Nupam P Mahajan · Washington University · R01 · FY2025 · CA

Targeting a Novel Signaling Nexus pACK/pCSK/pLCK in Immune Checkpoint Blockade (ICB)-Resistant Prostate Cancer

$484,364
Nupam P Mahajan · Washington University · R01 · FY2023 · CA

Lung Resident Mesenchymal Cells in the Pre-Metastatic Niche Formation

$484,308
Guangwen Ren · Jackson Laboratory · R01 · FY2021 · CA

Lung Resident Mesenchymal Cells in the Pre-Metastatic Niche Formation

$484,308
Guangwen Ren · Jackson Laboratory · R01 · FY2025 · CA

FEEDBACK CONTROL OF THE CELL CYCLE

$484,139
Harvard University · R37 · FY2002 · GM

Biochemical Studies of Human DNA Polymerase Delta

$484,099
New York Medical College · R01 · FY2004 · GM

Preclinical development and clinical monitoring of adoptive immune therapy

$483,898
Jeremy Rose · Division Of Basic Sciences - Nci · ZIC · FY2019 · CA

Chitinase-3-like-1 mediated immunosuppression in Glioblastoma

$483,859
Baoli Hu · University Of Pittsburgh At Pittsburgh · R01 · FY2023 · CA

Project 2: Combined CAR-T cell therapy

$483,710
Gianpietro Dotti · Univ Of North Carolina Chapel Hill · P50 · FY2023 · CA

Non-coding RNA regulation of Myeloid Cells

$483,706
Jorge Henao-Mejia · University Of Pennsylvania · R01 · FY2024 · CA

Targeting autophagy to enhance immune checkpoint inhibition

$483,579
Ravi K Amaravadi · Wistar Institute · P50 · FY2025 · CA

TLR Agonist Nano-Immune Therapy for Peritoneal Metastases

$483,556
Rita Elena Serda · University Of New Mexico Health Scis Ctr · R01 · FY2024 · CA

Membrane-based immunotherapy for triple negative breast cancer- a partnered approach

$483,484
Periasamy Selvaraj · Emory University · R01 · FY2018 · CA

Project 1: Overcoming therapeutic resistance in pancreatic cancer through epigenetic reprogramming

$483,451
Ronald M. Evans · Salk Institute For Biological Studies · P01 · FY2024 · CA

Estrogen Suppression as a Strategy to Enhance Immunotherapy Efficacy in EGFR-Mutated Non-Small Cell Lung Cancer

$483,395
Joseph Nicholas Bodor · Research Inst Of Fox Chase Can Ctr · R21 · FY2024 · CA