genome editing — grants

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17,054 grants matching “genome editing”

Therapeutic potential of CRISPR/Cas9 genome engineering in humanized mouse models

$662,130

Karl-Dimiter Bissig · Baylor College Of Medicine · R01 · FY2016 · HL

Applying a Human Liver Microphysiology System to Develop Therapeutic Strategies for Non-Alcoholic Fatty Liver Disease (NAFLD)

$662,067

D. Lansing Taylor · University Of Pittsburgh At Pittsburgh · R01 · FY2021 · DK

Deciphering unintended large gene modifications in gene editing for sickle cell disease

$662,035

Gang Bao · Rice University · R01 · FY2023 · HL

CRE Driver Strain Resources

$661,929

Stephen A Murray · Jackson Laboratory · R24 · FY2022 · OD

Nucleome Positioning System for Spatiotemporal Genome Organization and Regulation

$661,689

Yijun Ruan · Jackson Laboratory · U54 · FY2018 · DK

Identification and analysis of non-coding loci critical for cell viability and chromatin organization

$661,527

Wei Wang · University Of California, San Diego · R01 · FY2022 · HG

CAREER: Cell Specific Analysis of Conserved Spindle Orientation Factors

$661,433

Dan T Bergstralh · University Of Missouri-Columbia · · FY2024 · BIO

Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches

$661,392

Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2023 · CA

Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches

$660,909

Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2022 · CA

Site-specific Integration of Large (10-100 kb) DNA Constructs into the Mouse Genome and Human Induced Pluripotent Stem Cells Using the Cas9-Bxb1 Integrase Toolbox

$660,883

Vishnu Hosur · Jackson Laboratory · R01 · FY2025 · CA

National Xenopus Resource Center

$660,881

Marko E Horb · Marine Biological Laboratory · P40 · FY2023 · OD

TRANSCRIPTOME AND EPIGENOME MAPPING IN DOPAMINE NEURONS FROM THE OPIOID EXPOSED HUMAN BRAIN

$660,805

Schahram Akbarian · Icahn School Of Medicine At Mount Sinai · R01 · FY2023 · DA

Integrated high-throughput functional assays to identify ulcerative colitis causal risk variants

$660,725

Haiyuan Yu · Cornell University · R01 · FY2019 · DK

Generating Multiple Circuit and Neuron Type Specific AAV Vectors With Cross-Species Applicability

$660,686

Zhigang He · Boston Children'S Hospital · U01 · FY2016 · MH

Elucidating prostate cancer risk mechanisms through large-scale cistrome wide association studies

$660,477

Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2023 · CA

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

$660,307

Schahram Akbarian · Icahn School Of Medicine At Mount Sinai · U01 · FY2023 · DA

Variant to gene mapping for Alzheimer's Disease

$660,127

Struan F A Grant · Children'S Hosp Of Philadelphia · R01 · FY2017 · AG

Core I: iPSC Core

$659,996

Jerome S. Mertens · University Of California, San Diego · P30 · FY2025 · AG

Recombinant erythroid Kruppel-like factor fused to GATA1 upregulates globin expr

$659,879

Griffin Rodgers · National Heart, Lung, And Blood Institute · ZIA · FY2023 · HL

Next-generation computational/chemical methods for complex RNA structures

$659,862

Rhiju Das · Stanford University · R35 · FY2021 · GM

Comparative and functional analysis of conservation and rearrangement of topologically associating domains across mammals.

$659,729

Lucia Carbone · Oregon Health & Science University · R01 · FY2018 · HG

Phylogeny, historical biogeography, and floral ecological-evolutionary-developmental studies in Mariposa lilies and relatives (Calochortus, Liliaceae)

$659,707

Thomas J Givnish · University Of Wisconsin-Madison · · FY2019 · BIO

Therapeutic potential of CRISPR/Cas9 genome engineering in humanized mouse models

Applying a Human Liver Microphysiology System to Develop Therapeutic Strategies for Non-Alcoholic Fatty Liver Disease (NAFLD)

Deciphering unintended large gene modifications in gene editing for sickle cell disease

CRE Driver Strain Resources

Nucleome Positioning System for Spatiotemporal Genome Organization and Regulation

Identification and analysis of non-coding loci critical for cell viability and chromatin organization

CAREER: Cell Specific Analysis of Conserved Spindle Orientation Factors

Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches

Transcriptional Mechanisms of Human Insulin Resistance

Genetic regulation and immunological function of ERAP2 haplotypes

Functional Analysis of Human Breast Cancer Susceptibility Gene Variants

Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches

Site-specific Integration of Large (10-100 kb) DNA Constructs into the Mouse Genome and Human Induced Pluripotent Stem Cells Using the Cas9-Bxb1 Integrase Toolbox

National Xenopus Resource Center

TRANSCRIPTOME AND EPIGENOME MAPPING IN DOPAMINE NEURONS FROM THE OPIOID EXPOSED HUMAN BRAIN

Integrated high-throughput functional assays to identify ulcerative colitis causal risk variants

Generating Multiple Circuit and Neuron Type Specific AAV Vectors With Cross-Species Applicability

Elucidating prostate cancer risk mechanisms through large-scale cistrome wide association studies

Functional genomic resource and integrative model of dopaminergic circuitry associated with psychiatric disease

Variant to gene mapping for Alzheimer's Disease

Core I: iPSC Core

Recombinant erythroid Kruppel-like factor fused to GATA1 upregulates globin expr

Next-generation computational/chemical methods for complex RNA structures

Comparative and functional analysis of conservation and rearrangement of topologically associating domains across mammals.

Phylogeny, historical biogeography, and floral ecological-evolutionary-developmental studies in Mariposa lilies and relatives (Calochortus, Liliaceae)