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24,576 grants matching microbiome

CAREER: Microbial regulation of individual and social behaviors in honey bees

$802,839
Svjetlana Kruse · Rowan University · · FY2020 · BIO

Glycomic Modulation of Gut Microbiome During HIV Infection

$802,821
Mohamed Abdel Mohsen · Wistar Institute · R01 · FY2024 · DK

Longitudinal Neural Imaging and Functional Resilience After Hurricane Harvey

$802,801
Kjersti Marie Aagaard-Tillery · Baylor College Of Medicine · R21 · FY2020 · ES

The Jackson Laboratory Nathan Shock Center of Excellence in the Basic Biology of Aging

$802,687
Gary A Churchill · Jackson Laboratory · P30 · FY2017 · AG

The role of a bifunctional mucinase in modulating personalized gut microbiota-Vibrio cholerae interactions during infection

$802,423
Jun Zhu · University Of Pennsylvania · R01 · FY2023 · AI

The Role of the Microenvironment in Barrett's Esophagus

$802,412
Timothy Cragin Wang · Columbia University Health Sciences · U54 · FY2020 · CA

Technology Development Project - Increasing the complexity of ex vivo human airway models for studying immune response to viral infection

$802,385
Adam Williams · Jackson Laboratory · U19 · FY2024 · AI

Alanyl-glutamine supplementation of standard treatment for C. difficile infection

$802,321
Cirle Alcantara Warren · University Of Virginia · R01 · FY2020 · AI

Mechanisms of Chronic Inflammation in Periodontitis

$802,145
Niki Moutsopoulos · National Institute Of Dental & Craniofacial Research · ZIA · FY2025 · DE

Single Cell Dissection of Osteo-blasto/clasto-genic Lineage Cells for Osteoporosis

$802,132
Hong-Wen Deng · Tulane University Of Louisiana · U19 · FY2024 · AG

Computational and Systems Biology Core

$801,489
Rima F Kaddurah-Daouk · Duke University · U19 · FY2023 · AG

Human Respiratory Tract Microbiome in Health, HIV Infection and HIV Lung Disease

$801,433
Ronald G Collman · University Of Pennsylvania · U01 · FY2009 · HL

Genetic Epidemiology

$801,303
Alisa Goldstein · Division Of Cancer Epidemiology And Genetics · ZIA · FY2013 · CA

Flaxseed effects on hormones and lignans: role of race, genes, and gut microbiome

$801,302
Susan E McCann · Roswell Park Cancer Institute Corp · U01 · FY2012 · CA

Pathogenesis of Obstruction/Emphysema and the Microbiome (POEM) in HIV

$801,166
Alison Morris · University Of Pittsburgh At Pittsburgh · U01 · FY2009 · HL

Impact of HIV, oral microbiome and mycobiome on oral HPV persistence

$801,143
Robert D. Burk · Albert Einstein College Of Medicine · R01 · FY2024 · DE

MicroRNA Predictors of HIV Risk in Reproductive Age Women

$800,965
Raina N Fichorova · Brigham And Women'S Hospital · R01 · FY2022 · HD

Collaborative Research: Mapping interactions mediated by secondary metabolites in a fungus-growing ant microbiome

$800,857
Jonathan Klassen · University Of Connecticut · · FY2017 · BIO

Natural History of C. trachomatis urogenital and rectal infections

$800,761
Deborah Anne Dean · University Of California, San Francisco · R01 · FY2021 · AI

Improving Prediction of Chemotherapy-Induced Nausea: Integrating Genes, Behavior, and the Microbiome

$800,562
Heather S.l. Jim · H. Lee Moffitt Cancer Ctr & Res Inst · R01 · FY2018 · CA

Lung Microbiome in Cohorts of HIV-Infected Persons (Lung MicroCHIP) Study

$800,042
Laurence Huang · University Of California, San Francisco · U01 · FY2011 · HL

Natural History of C. trachomatis urogenital and rectal infections

$800,015
Deborah Anne Dean · University Of California, San Francisco · R01 · FY2022 · AI

UKRI/BBSRC-NSF/BIO: Identifying, elucidating and reprogramming synthetic microbial communities for degradation of toxic chemicals: microfluidics enabled high-throughput approaches

$800,000
Xiaoxia Lin · Regents Of The University Of Michigan - Ann Arbor · · FY2024 · BIO

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** POLYPHENOL-RICH HASKAP BERRIES (HASKAP) HAVE UNTAPPED THERAPEUTIC POTENTIAL TO IMPROVE HUMANHEALTH, AND AGRICULTURAL PRODUCERS IN NORTHERN U.S. STATES ARE POISED TO INCREASE PRODUCTION IFCONSUMER DEMAND INCREASES. A CRITICAL KNOWLEDGE GAP IS THAT LITTLE IS KNOWN ABOUT THE INTERACTIONSBETWEEN GUT MICROBES AND HASKAP POLYPHENOLS TO PRODUCE BIOACTIVE METABOLITES LINKED TODOWNSTREAM HEALTH IMPACTS. ADDITIONALLY, WE NEED TO KNOW WHICH HASKAP VARIETIES AND HARVESTTIMING WILL YIELD THE GREATEST BIOACTIVE POTENTIAL. THE LONG-TERM GOAL OF THIS PROJECT IS TO FORM APARTNERSHIP LINKING THE HEALTH IMPACTS OF HASKAP VARIETIES AND MANAGEMENT PRACTICES THAT MAXIMIZEHEALTH-PROMOTING COMPOUNDS TO BENEFIT BOTH CONSUMERS AND PRODUCERS. OUR OBJECTIVES ARE TODETERMINE 1) THE IMPACT OF HASKAP ON THE GUT MICROBIOME AND METABOLOME, 2) HOW GUT MICROBIOMECOMPOSITION AND PRODUCTION OF BIOACTIVE METABOLITES FROM HASKAP IMPACTS HEALTH AND INFLAMMATIONBIOMARKERS, AND 3) WHICH HASKAP VARIETIES AND GROWING PRACTICES INCREASE PRODUCTION OF HEALTH-PROMOTING COMPOUNDS. A FOUR-ARMED, RANDOMIZED, TRIPLE-BLIND, PLACEBO CONTROLLED CLINICAL TRIAL OFHASKAP VERSUS PLACEBO FOR TWO SEPARATE GROUPS WITH DISTINCTLY LOW AND HIGH METABOLIC SYNDROMESTATUS WILL BE COMPLETED. PARTICIPANTS WILL BE ASSESSED FOR HEALTH BIOMETRICS, GUT MICROBIOMECOMPOSITION, INFLAMMATION, AND BOTH THE GUT AND SERUM METABOLOME BEFORE AND AFTER 8 WEEKS OFINTERVENTION. HASKAP FRUIT FROM TWENTY VARIETIES WILL PRIMARILY COME FROM THE RANDOMIZED BLOCKDESIGN FIELD TRIAL AND FRUIT WILL BE HARVESTED AT FOUR STAGES OF FRUIT MATURITY, THEN ANALYZED FORPOLYPHENOL CONTENT. THIS PART OF THE STUDY WILL BE REPLICATED OVER THREE GROWING SEASONS.

$800,000
Montana State University · · FY2024 · National Institute of Food and Agriculture

Collaborative Research: MIM: Learning how mucus shapes and maintains microbiomes

$800,000
Katharina Ribbeck · Massachusetts Institute Of Technology · · FY2021 · BIO