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10,766 grants matching checkpoint inhibitor

Project 1: Targeting the Neutrophil Lineage To Enhance Immune Checkpoint Inhibitor Efficacy in NSCLC

$450,659
A. McGarry Houghton · Fred Hutchinson Cancer Research Center · P50 · FY2020 · CA

Targeting NQO1+ tumor to trigger innate and adaptive immunity

$450,508
Xiumei Huang · Indiana University Indianapolis · R01 · FY2022 · CA

MUC1-C is a target for advancing immunotherapy of non-small cell lung cancer

$450,429
Donald W. Kufe · Dana-Farber Cancer Inst · R21 · FY2024 · CA

Developing macrophage-based therapies for peripheral nerve injuries

$450,313
Brett M. Morrison · Johns Hopkins University · R21 · FY2023 · NS

Racial differences in Immunogenetic Tumorigenesis of Head and Neck Squamous Cell Carcinoma

$450,013
David Sidransky · Johns Hopkins University · R01 · FY2024 · CA

Cell-type specific inactivation of sumoylation during mouse spermatogenesis

$450,000
Margarita Vigodner · Yeshiva University · R15 · FY2019 · HD

Expanding the tumor antigen landscape and maintaining APCs in a T cell-activating state to restore tumor immunity

$449,997
Eduardo Davila · University Of Colorado Denver · R01 · FY2024 · CA

A novel nanobody-based agonist-redirected checkpoint (ARC) molecule, aPD1-Fc-OX40L, for cancer immunotherapy

$449,910
Maninder Sandey · Auburn University At Auburn · R15 · FY2023 · CA

Duke-UNC Chapel Hill Immunotherapy Training Grant

$449,807
Jonathan Stuart Serody · Univ Of North Carolina Chapel Hill · T32 · FY2018 · CA

Targeting autophagy to enhance immune checkpoint inhibition

$449,729
Ravi K Amaravadi · Wistar Institute · P50 · FY2023 · CA

Proteomic determinants of response to checkpoint blockade in malignant pleural mesothelioma

$449,641
Bryan Michael Burt · University Of California Los Angeles · R37 · FY2025 · CA

Modulation of tumor inflammatory factor for immune therapy

$449,561
Shu-Hsia Chen · Methodist Hospital Research Institute · R01 · FY2019 · CA

Project 3: Investigating new treatment approaches based on DNA repair vulnerability in ARID1A mutated type I ovarian cancer

$449,464
Stephanie Gaillard · Johns Hopkins University · P50 · FY2024 · CA

Genome-wide networks that modulate the T-lineage cell fate

$449,375
Cornelis Murre · Research Inst Of Fox Chase Can Ctr · P01 · FY2015 · AI

DNA Methylation Inhibitor Therapy for Testicular Cancer

$449,298
Michael J Spinella · University Of Illinois At Urbana-Champaign · R01 · FY2020 · CA

Targeting the PD-1H (VISTA) Pathway to Overcome Immunosuppression in Acute Myeloid Leukemia

$449,222
Xue Han · Ohio State University · R37 · FY2025 · CA

Intrapleural immunotherapeutic nanoparticles for MPE treatment

$449,180
Dawen Zhao · Wake Forest University Health Sciences · R01 · FY2023 · CA

Intrapleural immunotherapeutic nanoparticles for MPE treatment

$449,180
Dawen Zhao · Wake Forest University Health Sciences · R01 · FY2022 · CA

Preclinical Development of First-in-Class NDUFS7 Antagonists for the Treatment of Pancreatic Cancer

$449,119
Nouri Neamati · University Of Michigan At Ann Arbor · R01 · FY2024 · CA

Defining and Targeting Homologous Recombination Deficiency in Breast Cancer

$449,058
Simon N Powell · Sloan-Kettering Inst Can Research · P50 · FY2022 · CA

Development Therapeutics Branch Clinical Trials

$449,053
Yves Pommier · Division Of Basic Sciences - Nci · ZIA · FY2025 · CA

Novel mechanisms regulating PD-1 signaling and function

$448,861
Adam Mor · Columbia University Health Sciences · R01 · FY2024 · AI

Nutrient sensing and lysosomal signaling in regulatory T cells and immune tolerance

$448,750
Hongbo Chi · St. Jude Children'S Research Hospital · R01 · FY2022 · AI

Nutrient sensing and lysosomal signaling in regulatory T cells and immune tolerance

$448,750
Hongbo Chi · St. Jude Children'S Research Hospital · R01 · FY2023 · AI

Stroma penetrating and immune modulating nanoparticles for image-guided therapy of pancreatic cancer

$448,604
Lily Yang · Emory University · R01 · FY2024 · CA