Sort
17,054 grants matching “genome editing”
Epigenetics and 3D structure of miR-10b/HoxD locus in the brain and malignant glioma.
$630,137Anna M. Krichevsky · Brigham And Women'S Hospital · R01 · FY2022 · NS
Mechanisms Underlying Neuronal Enhancer Specification During Postnatal CNS Development
$630,106Michael E Greenberg · Harvard Medical School · R01 · FY2024 · NS
Approach for in vivo gene delivery into hematopoietic stem cells for hemophilia A therapy
$630,041Andre Michael Lieber · University Of Washington · R01 · FY2019 · HL
Multi-organism platform for functional assessment of human birth defect associated genomic variants
$629,950Lilianna Solnica-Krezel · Washington University · R01 · FY2024 · HD
Modeling Alzheimer's disease genetic variants in hiPSC
$629,844Jubao Duan · Endeavor Health Clinical Operations · R01 · FY2023 · AG
IDENTIFICATION AND PRECLINICAL EVALUATION OF NOVEL THERAPEUTIC APPROACHES TO DYSKERATOSIS CONGENITA
$629,822Frederick Bradley Johnson · University Of Pennsylvania · R01 · FY2022 · HL
Regulation of Opioid Sensitivity and Tolerance by Ubiquitin Ligase Signaling
$629,577Brock Grill · Seattle Children'S Hospital · R01 · FY2022 · DA
Caenorhabditis Intervention Testing Program: Interventions That Modulate Health, Longevity and Aging Hallmarks
$629,570Monica A. Driscoll · Rutgers, The State Univ Of N.J. · U01 · FY2022 · AG
Modeling mtDNA Disease in vivo
$629,508Stephen Carl Ekker · University Of Texas At Austin · R24 · FY2024 · OD
Modeling mtDNA Disease in vivo
$629,508Stephen Carl Ekker · University Of Texas At Austin · R24 · FY2025 · OD
Deciphering the Molecular Mechanism of Pediatric Interstitial Lung Disease to Advance Targeted Therapies
$629,498Jeremy Binder Katzen · University Of Pennsylvania · R01 · FY2025 · HL
HBB gene-editing for treating sickle cell disease
$629,375Gang Bao · Rice University · R01 · FY2020 · HL
Emerging multidrug resistance mechanisms in Campylobacter
$629,067Qijing Zhang · Iowa State University · R01 · FY2021 · AI
Emerging multidrug resistance mechanisms in Campylobacter
$629,067Qijing Zhang · Iowa State University · R01 · FY2023 · AI
Emerging multidrug resistance mechanisms in Campylobacter
$629,067Qijing Zhang · Iowa State University · R01 · FY2022 · AI
Uncovering the molecular and cellular mechanisms underlying AD using CRISPR/Cas9-edited isogenic neural cells
$628,647Yanhong Shi · Beckman Research Institute/City Of Hope · R56 · FY2019 · AG
Defining the epigenetic landscape in human prostate cancer
$628,587Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2015 · CA
Defining the epigenetic landscape in human prostate cancer
$628,587Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2016 · CA
ePACE: an automated system for high-throughput, closed-loop control of continuous molecular evolution to enable novel therapeutics
$628,580Ahmad Samir Khalil · Boston University (Charles River Campus) · R01 · FY2020 · EB
Human neurobehavioral phenotypes associates with the extended PWS/AS domain
$628,392Arthur L. Beaudet · Baylor College Of Medicine · R01 · FY2011 · HD
Regulation of diurnal rhythms in parvalbumin and perineuronal net function
$628,304Barbara A Sorg · Legacy Emanuel Hospital And Health Center · R01 · FY2025 · NS
Late Effects Prediction using Clinical Phenotypes and Whole Genome Sequencing
$628,281Yutaka Yasui · St. Jude Children'S Research Hospital · R01 · FY2020 · CA
Late Effects Prediction using Clinical Phenotypes and Whole Genome Sequencing
$628,281Yutaka Yasui · St. Jude Children'S Research Hospital · R01 · FY2021 · CA
Role of PPARG the PPARG Target Gene RBP7 in the Endothelium
$628,166Curt Daniel Sigmund · University Of Iowa · R01 · FY2016 · HL
Site-specific Integration of Large (10-100 kb) DNA Constructs into the Mouse Genome and Human Induced Pluripotent Stem Cells Using the Cas9-Bxb1 Integrase Toolbox
$627,839Vishnu Hosur · Jackson Laboratory · R01 · FY2024 · CA