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10,766 grants matching checkpoint inhibitor

Post-translational SOX2 modification - a regulatory switch between self-renewal and differentiation in squamous cell carcinoma

$435,586
Markus Schober · New York University School Of Medicine · R01 · FY2025 · CA

Photodynamic therapy with prior inhibition of epidermal growth factor receptor to stimulate antitumor innate immune response

$435,511
Theresa M Busch · University Of Pennsylvania · R01 · FY2023 · CA

Photodynamic therapy with prior inhibition of epidermal growth factor receptor to stimulate antitumor innate immune response

$435,511
Theresa M Busch · University Of Pennsylvania · R01 · FY2022 · CA

Intrapleural immunotherapeutic nanoparticles for MPE treatment

$435,429
Dawen Zhao · Wake Forest University Health Sciences · R01 · FY2024 · CA

Project 3. Overcoming Melanoma Treatment Resistance with Cytokine Immunotherapy

$435,370
Aaron Michael Ring · Yale University · P50 · FY2025 · CA

Project 2. Harnessing Epigenetic Regulation of Endogenous Retroelements in Melanoma

$435,370
Qin Yan · Yale University · P50 · FY2025 · CA

Project 3: Demethylation of HPV-associated head and neck cancer to trigger APOBEC synthetic lethality and enhance immune response

$435,036
Karen S Anderson · Yale University · P50 · FY2022 · DE

Race and ancestry as predictors of the tumor immune microenvironment and response to immunotherapy

$435,007
Elad Ziv · University Of California, San Francisco · P20 · FY2025 · CA

Immune Checkpoints and HPV-associated Head and Neck Cancers

$435,000
Sara Isabel Pai · Massachusetts General Hospital · R01 · FY2017 · DE

Overcoming the blood-brain barrier with nanoparticle vaccines against gliomas

$434,992
Elias Sayour · University Of Florida · R37 · FY2023 · CA

Deciphering MDSC function for GBM targeting

$434,936
Justin D. Lathia · Cleveland Clinic Lerner Com-Cwru · R01 · FY2021 · NS

Tackling Treg mediated resistance to radiation and anti-PDL1 in HNSCCs

$434,700
Sana D Karam · University Of Colorado Denver · R01 · FY2022 · DE

Mechanistic basis and therapeutic strategies for ARID1A mutation in ovarian cancer

$434,696
Rugang Zhang · Wistar Institute · R01 · FY2021 · CA

Targeting LSD1 to prevent therapy-induced transdifferentiation in BRAF mutant colorectal cancer

$434,552
Heather M O'Hagan · Indiana University Indianapolis · R01 · FY2025 · CA

Targeting exosomal PDL1 to improve immunotherapy

$434,375
Wei Guo · Wistar Institute · P50 · FY2021 · CA

Targeting PP4 to improve ovarian cancer response to immunotherapy

$434,357
Marion Curtis · Mayo Clinic Arizona · R37 · FY2024 · CA

Targeting Epigenomic Regulators at the Replication Fork in PDAC

$434,301
Gwen Lomberk · Medical College Of Wisconsin · R01 · FY2024 · CA

Role of Erbb3 kinase activity in colorectal tumorigenesis.

$434,298
Zhenghe Wang · Case Western Reserve University · R01 · FY2021 · CA

Autophagy mediated immune stimulation by reovirus in KRAS mutated colorectal cancer

$433,953
Radhashree Maitra · Yeshiva University · R15 · FY2022 · CA

Project 2: Combined CAR-T cell therapy

$433,764
Gianpietro Dotti · Univ Of North Carolina Chapel Hill · P50 · FY2022 · CA

High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancer

$433,516
Cesar M Castro · Massachusetts General Hospital · R01 · FY2023 · CA

Probing cellular, molecular and biomechanical barriers to immunotherapy in the tumor microenvironment with organotypic in vitro models of the tumor-lympho-immune interface

$433,439
Melody A Swartz · University Of Chicago · R01 · FY2021 · CA

The unique roles of the GTP-binding/protein crosslinking enzyme transglutaminase-2 and signaling partners in aggressive cancers

$433,417
Richard A. Cerione · Cornell University · R01 · FY2024 · CA

Project 3: Chemokine modulation in TME for enhanced TLS formation and cross-priming/ recruitment of therapeutic CD8+ TILs

$433,366
Walter J Storkus · Roswell Park Cancer Institute Corp · P01 · FY2023 · CA

Lung Cancer Vaccine

$433,293
Steven Monroe Lipkin · Weill Medical Coll Of Cornell Univ · U54 · FY2024 · CA