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17,828 grants matching crispr

ATP Binding Cassette Transporters in Health and Disease

$608,139
Elizabeth Joanna Tarling · University Of California Los Angeles · R01 · FY2022 · DK

Minimizing in vivo Drug Tolerance induction in tuberculosis.

$608,113
David G Russell · Rbhs-New Jersey Medical School · U19 · FY2021 · AI

Catalytic roles of RNA methyltransferase DIMT1

$608,084
Fange Liu · University Of Pennsylvania · R01 · FY2025 · HL

ePACE: an automated system for high-throughput, closed-loop control of continuous molecular evolution to enable novel therapeutics

$608,022
Ahmad Samir Khalil · Boston University (Charles River Campus) · R01 · FY2021 · EB

Deciphering epigenetically-regulated pathways to improve targeted therapy for invasion and metastasis in head and neck cancer

$607,981
Sidharth Venkata Puram · Washington University · R01 · FY2023 · DE

CRISPR-Cas13 gene therapy and RNA editing for Facioscapulohumeral muscular dystrophy (FSHD)

$607,917
Scott Q Harper · Research Inst Nationwide Children'S Hosp · R01 · FY2022 · AR

Evolvable essentiality in the pan-genome of Streptococcus pneumoniae and its mechanistic and evolutionary consequences

$607,872
Jason W. Rosch · St. Jude Children'S Research Hospital · R01 · FY2025 · AI

Evolvable essentiality in the pan-genome of Streptococcus pneumoniae and its mechanistic and evolutionary consequences

$607,872
Jason W. Rosch · St. Jude Children'S Research Hospital · R01 · FY2024 · AI

Mechanisms of genetic and non-genetic resistance to KRAS inhibition

$607,849
Lukas Edward Dow · Weill Medical Coll Of Cornell Univ · R01 · FY2025 · CA

Lrp4 signaling in bone metabolism and mechanotransduction

$607,734
Alexander G Robling · Indiana University Indianapolis · R01 · FY2021 · AR

Development of scalable methods for rapid phenotyping and functional testing of variants

$607,682
Gaurav K Varshney · Oklahoma Medical Research Foundation · R24 · FY2024 · OD

Development and maintenance of chronic toxoplasmosis

$607,619
Sebastian Lourido · Whitehead Institute For Biomedical Res · R01 · FY2025 · AI

FEN1 Endonuclease as a Synthetic Lethal Target for Cancer Therapy

$607,512
Richard D Kolodner · University Of California, San Diego · R01 · FY2024 · CA

Molecular mechanism of thyroid hormone receptor function during metamorphosis

$607,473
Yun-Bo Shi · Eunice Kennedy Shriver National Institute Of Child Health & Human Development · ZIA · FY2015 · HD

Functional long noncoding RNAs in neural development

$607,426
Daniel A Lim · University Of California, San Francisco · R01 · FY2025 · NS

Regulatory Role of Tandem Tryptophan Codons in Chlamydial Persistence

$607,417
Reynaldo A Carabeo · University Of Nebraska Medical Center · R01 · FY2023 · AI

Regulatory Role of Tandem Tryptophan Codons in Chlamydial Persistence

$607,417
Reynaldo A Carabeo · University Of Nebraska Medical Center · R01 · FY2021 · AI

The role of apolipoprotein E in Alzheimer's adaptive immunity

$607,408
David Gate · Northwestern University At Chicago · R01 · FY2024 · AG

The role of apolipoprotein E in Alzheimer's adaptive immunity

$607,408
David Gate · Northwestern University At Chicago · R01 · FY2022 · AG

The role of apolipoprotein E in Alzheimer's adaptive immunity

$607,408
David Gate · Northwestern University At Chicago · R01 · FY2023 · AG

Elucidating the path to type I IFNs in TB infection

$607,300
Amy K Barczak · Massachusetts General Hospital · R01 · FY2022 · AI

Identifying causal variants and genes underlying breast cancer risk loci

$606,904
Matthew L Freedman · Dana-Farber Cancer Inst · R01 · FY2018 · CA

Investigating neurodevelopmental toxicity of perfluoroalkyl acids and their derivatives in human brain organoids models

$606,887
Lilia M Iakoucheva · University Of California, San Diego · R01 · FY2022 · ES

THE IMMUNE SELF-ASSOCIATED STORAGE ORGANELLE (SASO)

$606,836
Matthew F Krummel · University Of California, San Francisco · R01 · FY2023 · AI

Search for obesity-associated genes with protective effects on metabolic health

$606,634
Ruth Jf Loos · Icahn School Of Medicine At Mount Sinai · R01 · FY2017 · DK