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10,766 grants matching checkpoint inhibitor

Studies of DNA damage checkpoints

$418,239
Paul R Russell · Scripps Research Institute, The · R01 · FY2007 · CA

Probing cellular, molecular and biomechanical barriers to immunotherapy in the tumor microenvironment with organotypic in vitro models of the tumor-lympho-immune interface

$418,234
Melody A Swartz · University Of Chicago · R01 · FY2024 · CA

Immune Checkpoints in Acute Respiratory Distress Syndrome (IC-ARDS)

$418,197
Carmen R Mikacenic · Benaroya Research Inst At Virginia Mason · R01 · FY2024 · HL

Project 3: The ATM Kinase as a Therapeutic Target in Drug Resistant NSCLC with Brain Metastasis

$418,152
Don X Nguyen · Yale University · P50 · FY2025 · CA

Small Molecule Activators of Procaspases as Anti-Cancer Agents

$417,934
Paul Hergenrother · University Of Illinois At Urbana-Champaign · R01 · FY2018 · CA

Cell surface receptor targeted therapies for brain tumors

$417,858
Khalid A Shah · Brigham And Women'S Hospital · R01 · FY2025 · CA

Evaluation of Immune-based Combinations in Prostate Cancer

$417,740
Ravi Madan · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Nanocage-based systemic delivery of TGFb trap for immunomodulation of brain neoplasms

$417,726
Jung Soo Suk · University Of Maryland Baltimore · R01 · FY2025 · NS

Targeting mechanisms of immune evasion in chemotherapy-induced senescent cells

$417,650
James Jackson · Tulane University Of Louisiana · R01 · FY2025 · CA

INTERACITONS OF HPV ONCOGENES WITH THE P53 PATHWAY

$417,514
Fred Hutchinson Cancer Research Center · R01 · FY2001 · CA

Overcoming Resistance Mechanisms to Anaplastic Lymphoma Kinase Inhibitors

$417,500
Aaron N Hata · Massachusetts General Hospital · R01 · FY2023 · CA

Overcoming Resistance Mechanisms to Anaplastic Lymphoma Kinase Inhibitors

$417,500
Aaron N Hata · Massachusetts General Hospital · R01 · FY2025 · CA

REGULATION AND ADAPTIVE MECHANISMS OF ONCOGENIC RAS/ERK SIGNALING

$417,319
Poulikos I Poulikakos · Icahn School Of Medicine At Mount Sinai · R01 · FY2021 · CA

Role of microbial-modulated bile acid receptor signaling in breast cancer

$417,301
Liza Makowski Hayes · University Of Tennessee Health Sci Ctr · R01 · FY2020 · CA

Replication Associated Genetic Rearrangements

$417,145
Brandeis University · R01 · FY2003 · GM

Project 1: Glutaminolytic GDH1 activation-dependent immunotherapy resistance in LKB1-mutant lung adenocarcinoma

$416,967
Sumin Kang · Emory University · P01 · FY2023 · CA

Metabolic interactions between tumor cells and the immunce system in GBM A potential Achilles heel of GBM for novel therapeutics

$416,964
Loic Pierre Deleyrolle · University Of Florida · R01 · FY2023 · NS

Project 3 Immunotherapeutic Targeting of SLC45A2 for Treatment of Uveal Melanoma

$416,787
Cassian Yee · University Of Tx Md Anderson Can Ctr · P50 · FY2019 · CA

Project 3 Immunotherapeutic Targeting of SLC45A2 for Treatment of Uveal Melanoma

$416,783
Cassian Yee · University Of Tx Md Anderson Can Ctr · P50 · FY2022 · CA

Deciphering MDSC function for GBM targeting

$416,765
Justin D. Lathia · Cleveland Clinic Lerner Com-Cwru · R01 · FY2019 · NS

Genetic Mechanisms Controlling Kidney Cancer Immune Escape

$416,677
Haydn Kissick · Emory University · R01 · FY2025 · CA

Oncolytic virus therapeutic responses occur from changes in the glioblastoma immune microenvironment

$416,647
E. Antonio Chiocca · Brigham And Women'S Hospital · R01 · FY2020 · NS

Systemic delivery of an oncolytic adenovirus targeting TGFβ to enhance anti-PD-1 and anti-CTLA-4 therapy for triple negative breast cancer

$416,290
Weidong Xu · Endeavor Health Clinical Operations · R01 · FY2025 · CA

Double-Strand Break Sensing, Signaling, and Repair

$416,261
John A Tainer · University Of Calif-Lawrenc Berkeley Lab · P01 · FY2012 · CA

Tumor Suppressor Qualities and Mechanisms of LZAP Activity

$416,250
Wendell G Yarbrough · Yale University · R01 · FY2016 · DE