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17,828 grants matching crispr

Investigating neurodevelopmental toxicity of perfluoroalkyl acids and their derivatives in human brain organoids models

$602,132
Lilia M Iakoucheva · University Of California, San Diego · R01 · FY2024 · ES

Evaluation of the AMPK-BACH1-NRF2 Axis as a Therapeutic Target for Inherited DCM

$602,080
Mark Mercola · Stanford University · R01 · FY2024 · HL

Guarding the Genome: Aneuploidy and tumorigenesis

$601,980
Don W. Cleveland · Ludwig Institute For Cancer Res Ltd · R01 · FY2016 · GM

Epigenetic Therapy to Treat Radiation-induced Xerostomia

$601,942
Isabelle M.a. Lombaert · University Of Michigan At Ann Arbor · R01 · FY2025 · DE

Catalytic roles of RNA methyltransferase DIMT1

$601,932
Fange Liu · University Of Pennsylvania · R01 · FY2022 · HL

Bioanalytic Core

$601,853
Mar M Sanchez · Emory University · P50 · FY2022 · MH

Elucidating Genotype-Phenotype Relationship of Polygenic Dilated Cardiomyopathies

$601,810
Joseph C Wu · Stanford University · R01 · FY2023 · HL

Project 3 - Modulation of Antiviral Immunity and T cell Exhaustion by Inhibitory Receptors

$601,739
E. John Wherry · University Of Pittsburgh At Pittsburgh · P01 · FY2025 · AI

Evolvable essentiality in the pan-genome of Streptococcus pneumoniae and its mechanistic and evolutionary consequences

$601,612
Jason W. Rosch · St. Jude Children'S Research Hospital · R01 · FY2023 · AI

Neurobiology for Lac-Phe Hypophagia

$601,556
Yong Xu · Baylor College Of Medicine · R01 · FY2024 · DK

Development of Advanced Preclinical Models for Pediatric Solid Tumors

$601,492
Eric Alejandro Sweet-Cordero · University Of California, San Francisco · R01 · FY2021 · CA

3/11 Epigenetic Regulation of Neuroimmune Pathways

$601,471
Sean P Farris · University Of Pittsburgh At Pittsburgh · U01 · FY2022 · AA

NRF2 suppression of inflammatory signaling and its role in tumor progression

$601,353
James V Alvarez · Fred Hutchinson Cancer Center · R01 · FY2025 · CA

Targeting c-Myc stability in c-Myc overexpressing large B-cell lymphoma

$601,346
Lapo Alinari · Ohio State University · R01 · FY2022 · CA

Ribosomal Frameshifting in HIV-1 Infection, Inflammation and Neurotoxicity

$601,307
Yiping Zhu · University Of Rochester · R01 · FY2025 · NS

Discovering the mechanisms underlying oncogenesis by ZFTA-RELA and pinpointing therapeutic targets.

$601,250
Stephen C Mack · St. Jude Children'S Research Hospital · U01 · FY2024 · CA

Discovering the mechanisms underlying oncogenesis by ZFTA-RELA and pinpointing therapeutic targets.

$601,250
Stephen C Mack · St. Jude Children'S Research Hospital · U01 · FY2025 · CA

Family Study of Carotid Atherosclerosis and Stroke Risk

$601,029
Tatjana Rundek · University Of Miami School Of Medicine · R01 · FY2018 · NS

A nucleus-to-mitochondria nucleic acid-sensing pathway prevents bypass of age-associated proliferative boundaries

$601,017
Jan Karlseder · Salk Institute For Biological Studies · R01 · FY2025 · AG

Understanding the Molecular Genetic Mechanisms of Asthma Risk Loci: IL33, IL1RL1, and GSDMB

$600,961
Erin D. Gordon · University Of California, San Francisco · R01 · FY2021 · AI

Genome Wide Association Study for Childhood Obesity

$600,750
Struan F A Grant · Children'S Hosp Of Philadelphia · R01 · FY2023 · HD

Targeting Glycogen Metabolism in Ewing's Sarcoma: Diagnostic, Prognostic, and Therapeutic Applications

$600,688
Ramon C. Sun · University Of Florida · R01 · FY2024 · CA

Therapeutic strategies for microsatellite expansion diseases using RNA-targeting CRISPR/Cas

$600,524
Eugene Wei-Ming Yeo · University Of California, San Diego · R01 · FY2020 · NS

Mechanisms of DUX4 mediated FSHD pathology

$600,403
Peter L Jones · University Of Nevada Reno · R01 · FY2022 · AR

Developmental Functional Genomics in ASD Toddlers

$600,336
Eric Courchesne · University Of California, San Diego · R01 · FY2017 · MH