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24,576 grants matching microbiome

Role of the microbiome in HIV vaccine induced heterogeneity

$739,661
James G. Kublin · Fred Hutchinson Cancer Research Center · R01 · FY2019 · AI

COBRE-Administrative Core

$739,596
Richard J Lamont · University Of Louisville · P20 · FY2018 · GM

COBRE-Administrative Core

$739,596
Richard J Lamont · University Of Louisville · P20 · FY2019 · GM

Identification of the Exposome in Fatty Liver Disease in Mexican American Families Using Genetic Correction

$739,578
John Blangero · University Of Texas Rio Grande Valley · R01 · FY2019 · MD

Resilience to obesity in carriers of monogenic obesity mutations - a study on the underlying mechanisms

$739,547
Ruth Jf Loos · Icahn School Of Medicine At Mount Sinai · R01 · FY2020 · DK

Functional Genomics Core

$739,509
Anthony Haag · University Of Texas Hlth Sci Ctr Houston · P01 · FY2020 · AI

Using bile salt metabolism to modulate CDI prophylaxis

$739,487
Ernesto V Abel-Santos · University Of Nevada Las Vegas · R01 · FY2024 · AI

DROUGHT IS ONE OF THE MOST HARMFUL WEATHER DISASTERS WITH RESPECT TO AGRICULTURAL PRODUCTIVITY IN THE US, WITH THE ECONOMIC COSTS OF THESE EVENTS EXPECTED TO INCREASE AS DROUGHTS ARE MORE FREQUENT AND INTENSE IN THE FUTURE. IMPROVED UNDERSTANDING OF HOW THE SOIL MICROBIOME (E.G., BACTERIA AND FUNGI THAT INHABIT THE SOIL ENVIRONMENT) RESPONDS TO INCREASED FREQUENCY AND INTENSITY OF DROUGHT MAY PROVIDE INSIGHT VALUABLE FOR MITIGATING THESE LOSSES AND SUSTAINING AGRO-ECOSYSTEM FUNCTIONS. RANGELANDS, WHICH PROVIDE VALUABLE ECOSYSTEM SERVICES SUCH AS FORAGE PRODUCTION FOR LIVESTOCK, ARE PARTICULARLY PRONE TO DROUGHT. RECENT RESEARCH SUGGESTS THAT BOTH PLANTS AND SOIL MICROBES RESPOND STRONGLY TO EXPERIMENTAL DROUGHT IN US RANGELANDS. THUS, OUR GOAL IS TO ASSESS HOW DROUGHT-INDUCED CHANGES IN SOIL MICROBES AND THE INTERACTION BETWEEN PLANTS AND SOIL MICROBES INFLUENCES IMPORTANT ECOSYSTEM SERVICES, SUCH AS FORAGE PRODUCTION. WE WILL USE EXISTING EXPERIMENTAL INFRASTRUCTURE TO IMPOSE DROUGHT IN THREE MAJOR RANGELANDS OF THE CENTRAL US - SHORTGRASS STEPPE IN NORTHEASTERN CO, MIXED GRASS PRAIRIE IN WESTERN KS, AND TALLGRASS PRAIRIE IN NORTHEASTERN KS. FOR EACH RANGELAND, WE WILL COMPARE HOW PLANTS AND SOIL MICROBES RESPOND TO DROUGHT OVER TIME, ASSESS HOW CHANGES IN THE SOIL MICROBES AFFECTS THE MOST ABUNDANT GRASS SPECIES IN EACH RANGELAND AND VICE VERSA, AND QUANTIFY HOW RESPONSES OF PLANTS AND SOIL MICROBES TO A DROUGHT AFFECT FUTURE RESPONSES TO DROUGHT. OUR PROPOSED RESEARCH ADDRESSES THE CORE OBJECTIVES OF THE AGRICULTURAL MICROBIOMES PROGRAM AREA PRIORITY BY CHARACTERIZING AGRICULTURAL MICROBIOMES, MICROBIOME FUNCTIONS AND HOST-MICROBIOME INTERACTIONS THAT CONFER DROUGHT TOLERANCE.

$739,464
Colorado State University · · FY2020 · National Institute of Food and Agriculture

Hippocampal Inflammation as a Pathophysiology for Psychosis

$739,459
Dolores Malaspina · Icahn School Of Medicine At Mount Sinai · R01 · FY2019 · MH

Hippocampal Inflammation as a Pathophysiology for Psychosis

$739,368
Dolores Malaspina · Icahn School Of Medicine At Mount Sinai · R01 · FY2018 · MH

The role of the urethral microbiome in idiopathic urethritis in men

$739,341
David Emmet Nelson · Indiana University Indianapolis · R01 · FY2016 · AI

Gut Microbiota-Mediated Inflammatory Interactions Between Alcohol Use Disorders and HIV Infection

$739,324
Ali Keshavarzian · Rush University Medical Center · R01 · FY2023 · AA

Monitoring Social Change: Dynamics Of Aging And Cognitive Function

$739,218
Barry M Popkin · Univ Of North Carolina Chapel Hill · R01 · FY2021 · AG

Research Project 1 - Hepatocellular Genetic Epidemiology of Fatty Liver Disease in Hispanics

$739,200
Joanne E Curran · University Of Texas Rio Grande Valley · U54 · FY2023 · HG

Testing sex as a moderator of health impacts of upward mobility on indicators for AD risk in young adulthood

$739,186
Bridget L Callaghan · University Of California Los Angeles · R01 · FY2025 · AG

Repurposing of Metormin for Older Patients with HFpEF

$739,149
Dalane W Kitzman · Wake Forest University Health Sciences · U01 · FY2023 · AG

Host Defense Training in Allergy and Infectious Diseases

$739,141
David Neal Fredricks · University Of Washington · T32 · FY2022 · AI

CAREER: Linking Microbial Phylogenetic and Functional Gene Diversity to Microbial Mat Ecosystem Function Following Environmental Disturbance

$739,000
Robert S Norman · University South Carolina Research Foundation · · FY2012 · BIO

Dietary Etiologies of Heart Disease

$738,932
Eric B Rimm · Harvard School Of Public Health · R01 · FY2022 · HL

Urban Water Systems, Enteric Pathogen Distribution & Gut Microbiome Development in Children: A Natural Experiment in Mozambique

$738,842
Matthew C Freeman · Emory University · R01 · FY2020 · AI

The Gut Microbiota in Metabolic Surgery: A Multi-Ethnic, Multi-Omic, Longitudinal Study

$738,831
Danxia Yu · Vanderbilt University Medical Center · R01 · FY2023 · DK

Center for Excellence in Host Pathogen Interactions

$738,765
David S. Bradley · University Of North Dakota · P20 · FY2025 · GM

Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases

$738,651
Adriana H Tremoulet · University Of California, San Diego · U54 · FY2017 · HD

RAISE-SitS: Designing models to forecast how biogeochemical fluctuations in soil systems govern soil development, terrestrial water storage and ecosystem nutrient fluxes

$738,562
Pamela L Sullivan · University Of Kansas Center For Research Inc · · FY2018 · GEO

Novel Pathways for Kidney Stone Formation

$738,557
Eric N Taylor · Brigham And Women'S Hospital · R01 · FY2020 · DK