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10,766 grants matching checkpoint inhibitor

Project 3. Overcoming Melanoma Treatment Resistance with Cytokine Immunotherapy

$414,525
Aaron Michael Ring · Yale University · P50 · FY2024 · CA

Project 2. Harnessing Epigenetic Regulation of Endogenous Retroelements in Melanoma

$414,525
Qin Yan · Yale University · P50 · FY2024 · CA

LILRB modulates tumor microenvironment and promotes tumor progression

$414,496
Shu-Hsia Chen · Methodist Hospital Research Institute · R01 · FY2022 · CA

Arming Oncolytic HSV Vectors to Induce Anti-GBM Immune Responses in Syngeneic Mice

$414,488
Joseph C. Glorioso · University Of Pittsburgh At Pittsburgh · R01 · FY2018 · CA

A Mouse Model to Assess Long Term Immunotherapy-related Adverse Effects in Children

$414,188
Yin Wang · University Of Maryland Baltimore · R01 · FY2021 · CA

Checkpoints of TNF Gene Regulation

$414,000
Anne Goldfeld · Immune Disease Institute, Inc. · R01 · FY2011 · GM

Investigating a Novel Inhibitory Receptor in Regulating CAR-T Cell Persistence and Function

$413,971
Li Lily Wang · Cleveland Clinic Lerner Com-Cwru · R21 · FY2024 · CA

Project 3: Chronic interferon and bile acid signaling as drivers of immunosuppression in age-related liver cancer

$413,965
Susan M Kaech · Sanford Burnham Prebys Medical Discovery Institute · P01 · FY2024 · AG

Project 2: Cytoplasmic chromatin fragments (CCF) as a driver of liver cancer and target for intervention during aging

$413,965
Peter D. Adams · Sanford Burnham Prebys Medical Discovery Institute · P01 · FY2024 · AG

Platelets-Mediated Delivery of Checkpoint Inhibitors for Post-Surgical Cancer Immunotherapy

$413,953
Song Li · University Of California Los Angeles · R01 · FY2021 · CA

Mechanism-Based Use of Chk1 Inhibitors in Pancreas Cancer

$413,920
Jonathan Maybaum · University Of Michigan At Ann Arbor · R01 · FY2010 · CA

Project 1: Targeting immunotherapy-induced resistance with DC vaccination and PD-1/CSF-1R inhibition

$413,778
Robert M Prins · University Of California Los Angeles · P50 · FY2024 · CA

Role of MetAP-2 in Angiogenesis and Wnt Signaling

$413,750
Craig M Crews · Yale University · R01 · FY2009 · CA

Mre11-Dependent DNA Damage Responses in Breast Cancer Pathogenesis

$413,651
Gaorav P. Gupta · Univ Of North Carolina Chapel Hill · R37 · FY2023 · CA

Targeting exosomal PDL1 to improve immunotherapy

$413,618
Wei Guo · Wistar Institute · P50 · FY2023 · CA

E3 ligase mediated control of Foxp3 expression and immune suppression-mechanisms and potential as immunotherapeutic target

$413,515
Drew M. Pardoll · Johns Hopkins University · R01 · FY2021 · AI

E3 ligase mediated control of Foxp3 expression and immune suppression-mechanisms and potential as immunotherapeutic target

$413,515
Drew M. Pardoll · Johns Hopkins University · R01 · FY2019 · AI

E3 ligase mediated control of Foxp3 expression and immune suppression-mechanisms and potential as immunotherapeutic target

$413,515
Drew M. Pardoll · Johns Hopkins University · R01 · FY2020 · AI

Role of microbiota in therapy to ovarian cancer

$413,353
Troy D Randall · University Of Alabama At Birmingham · R01 · FY2019 · CA

Project 4: Interrogating and harnessing age-related IFN signaling and innate immunity in HCC prevention and therapy

$413,341
Gen-Sheng Feng · Sanford Burnham Prebys Medical Discovery Institute · P01 · FY2022 · AG

HSP90 AS A TARGET FOR MECHANISM-BASED THERAPY FOR CASTRATION-RESISTANT PROSTATE C

$413,330
Neal Rosen · Sloan-Kettering Inst Can Research · P50 · FY2007 · CA

Discoidin Domain Receptor Tyrosine Kinase 2 in bladder cancer progression

$413,325
Dan Theodorescu · Cedars-Sinai Medical Center · R01 · FY2021 · CA

Discoidin Domain Receptor Tyrosine Kinase 2 in bladder cancer progression

$413,325
Dan Theodorescu · Cedars-Sinai Medical Center · R01 · FY2023 · CA

Therapeutic Targeting of Breast Cancer Tumor Initiating Cells

$413,297
Charles M Perou · Univ Of North Carolina Chapel Hill · R01 · FY2021 · CA

Therapeutic Targeting of Breast Cancer Tumor Initiating Cells

$413,297
Charles M Perou · Univ Of North Carolina Chapel Hill · R01 · FY2025 · CA