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24,576 grants matching “microbiome”
Metagenomic profiling of oral polymicrobial flora in head and neck cancers
$738,556Charis Eng · Cleveland Clinic Lerner Com-Cwru · R01 · FY2010 · DE
Center for Mucosal Immunobiology and Rheumatic Disease Pathogenesis
$738,482V Michael Holers · University Of Colorado Denver · P30 · FY2024 · AR
Gut Microbiota and Effect on Immune Suppressants in Transplantation
$738,472Ajay K Israni · Hennepin Healthcare Research Institute · R01 · FY2019 · AI
Maternal Stress and the Gut-Brain Axis in African American Infants
$738,378Elizabeth J Corwin · Emory University · R01 · FY2015 · MD
Repurposing of Metormin for Older Patients with HFpEF
$738,245Dalane W Kitzman · Wake Forest University Health Sciences · U01 · FY2024 · AG
Predicting the multi-omic impact of psychiatric GWAS associations
$738,209Laura Marianne Huckins · Icahn School Of Medicine At Mount Sinai · R01 · FY2021 · MH
Project 3 Population studies of major human fungal pathogens: genomic and transcriptomic analyses of interactions with the host and microbiome and the rise of antifungal resistance
$738,128Christina A Cuomo · Broad Institute, Inc. · U19 · FY2019 · AI
A cross-sectional and longitudinal study of gut microbiota in Parkinson's disease
$738,000Tao Xie · University Of Chicago · U01 · FY2025 · DK
Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer
$737,926Terryl Johnson Hartman · Emory University · R01 · FY2022 · CA
The role of penile bacteria and inflammation in HIV susceptibility; Rakai, Uganda
$737,812Lance Bradley Price · George Washington University · R01 · FY2016 · AI
3D Bioprinted skin models for drug screening
$737,751Marc Ferrer-Alegre · National Center For Advancing Translational Sciences · ZIA · FY2021 · TR
Early Childhood Diet, Growth, Gut Microbiome And Lung Health in Cystic Fibrosis
$737,740Huichuan J Lai · University Of Wisconsin-Madison · R01 · FY2016 · DK
The microbiome and aging in Clostridioides difficile infection
$737,382Vincent B Young · University Of Michigan At Ann Arbor · R01 · FY2023 · AI
Oral Microbiome and Periodontitis: A Prospective Study in Postmenopausal Women
$737,279Jean Wactawski-Wende · State University Of New York At Buffalo · R01 · FY2018 · DE
Host genetics, early-life microbiome, and childhood asthma: MARC-43 Boston
$737,243Carlos A. Camargo · Massachusetts General Hospital · UH3 · FY2025 · OD
Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
$737,192James Gregory Caporaso · Northern Arizona University · U24 · FY2022 · CA
Instrumentation for Noninvasive Measurement of Glucose and Energy Balance in Mice with Continuous Glucose Telemetry and Indirect Calorimetry
$737,103Alexander Banks · Beth Israel Deaconess Medical Center · S10 · FY2020 · OD
Targeted Microbiome Transplant in Atopic Dermatitis
$736,927Richard L Gallo · National Jewish Health · U19 · FY2016 · AI
Lung Transplant Microbiome and Chronic Allograft Dysfunction
$736,861Ronald G Collman · University Of Pennsylvania · R01 · FY2014 · HL
Gut microbiota and human malaria
$736,859Nathan Schmidt · Indiana University Indianapolis · R01 · FY2021 · AI
POTASSIUM (K) IS AN ESSENTIAL MACRONUTRIENT FOR PLANTS. SINCE ONLY A SMALL FRACTION OF THE SOIL K CONTENT IS PLANT AVAILABLE, PLANTS MUST DEVELOP EFFICIENT STRATEGIES FOR ITS UPTAKE FROM THE SOIL. THE MOST IMPORTANT STRATEGY USED BY PLANTS TO ACQUIRE NUTRIENTS IS THE ARBUSCULAR MYCORRHIZAL (AM) SYMBIOSIS, A MUTUALISTIC ASSOCIATION BETWEEN THE MAJORITY OF LAND PLANTS AND UBIQUITOUS SOIL FUNGI. WE HAVE RECENTLY DEMONSTRATED THAT AM FUNGI CAN ALSO HAVE A POSITIVE IMPACT ON LEGUME K NUTRITION, BUT THE PHYSIOLOGICAL AND MOLECULAR MECHANISMS UNDERPINNING THIS SYMBIOTIC EXCHANGE ARE ONLY POORLY UNDERSTOOD.THE OVERALL OF THIS PROJECT IS TO (1) DEMONSTRATE THE FACTORS THAT AFFECT K TRANSLOCATION THROUGH AM FUNGAL HYPHAE, (2) CHARACTERIZE THE SIGNIFICANCE OF FUNGAL K TRANSPORT FOR THE RESOURCE EXCHANGE PROCESSES BETWEEN PLANTS AND AM FUNGI IN LABORATORY AND FIELD EXPERIMENTS, (3) IDENTIFY PLANT GENES THAT ARE DIRECTLY INVOLVED IN MYCORRHIZAL-DEPENDENT K NUTRITION, AND (4) FUNCTIONALLY CHARACTERIZE KEY CANDIDATE GENES THAT CONTROL K FLUX FROM THE SOIL TO LEGUME ROOTS THROUGH THE AM SYMBIOSIS.AS LAND GRANT UNIVERSITIES, NORTH CAROLINA STATE UNIVERSITY AND SOUTH DAKOTA STATE UNIVERSITY APPLY THEIR RESEARCH TO BENEFIT THE ECONOMIC, INTELLECTUAL, AND SOCIAL ENDEAVORS OF CITIZENS. OUR PROJECT WILL PROVIDE FUNDAMENTAL INSIGHTS INTO THE MOLECULAR MECHANISMS GOVERNING THE SYMBIOTIC ACQUISITION OF K, AND THIS IS CRITICAL TO DEVELOPING NEW STRATEGIES TO REDUCE THE DEPENDENCE ON ENERGY-INTENSIVE CHEMICAL FERTILIZERS. OUR PROJECT ADDRESSES THE "AGRICULTURAL MICROBIOMES" AREA PRIORITY BY INVESTIGATING HOW THE MICROBIO-COMPONENTS OF AGRICULTURAL SYSTEMS CAN BE MANAGED TO IMPROVE CROP PRODUCTIVITY AND RESILIENCE TO LOW NUTRIENT AVAILABILITY.
$736,848North Carolina State University · · FY2020 · National Institute of Food and Agriculture
The Genomics and Antagonism of Pathobiont Colonization
$736,728Anthony W Maresso · Baylor College Of Medicine · U19 · FY2021 · AI
The impact of gastric bypass on maternal and offspring metabolic health
$736,601Paul Kievit · Oregon Health & Science University · R01 · FY2021 · DK
Ontology-based aPplications of mUlti-discipLinary knowlEdge on orodeNtal Conditions and outcomEs (OPULENCE)
$736,507Amy Catherine Moreno · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · DE
Microbiome Influences on Asthma-Related Outcomes in Early Life
$736,399Fernando D Martinez · University Of Arizona · P01 · FY2020 · AI