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17,828 grants matching crispr

Using evolutionary variation to probe the neural basis for behavior

$591,892
Vanessa Ruta · Rockefeller University · R35 · FY2024 · NS

Mode of Action Core

$591,851
Bruce Steven Klein · University Of Wisconsin-Madison · U19 · FY2021 · AI

Regulators of Cancer Immunotherapy Response

$591,752
Kai W Wucherpfennig · Dana-Farber Cancer Inst · R01 · FY2020 · CA

Understanding the Molecular Genetic Mechanisms of Asthma Risk Loci: IL33, IL1RL1, and GSDMB

$591,738
Erin D. Gordon · University Of California, San Francisco · R01 · FY2022 · AI

Functional Significance of individual p53 mutations in determining the role of estrogen receptor beta in triple negative breast cancer

$591,642
Gokul M Das · Roswell Park Cancer Institute Corp · R01 · FY2023 · CA

Nonviral Delivery of CRISPR-Cas9 into Hepatocytes Combined with APAP Selection for Treatment of Familial Hypercholesterolemia

$591,640
Renee Nicole Cottle · Clemson University · R01 · FY2024 · HL

FEN1-Nuclease-Targeted Therapy for Ewing Sarcoma

$591,603
Richard D Kolodner · University Of California, San Diego · R01 · FY2023 · CA

Systems Immunogenetics of Influenza Virus Infection in the Collaborative Cross

$591,594
Mark T Heise · Univ Of North Carolina Chapel Hill · U19 · FY2017 · AI

Dissecting AAV silencing in humanized mice

$591,564
Karl-Dimiter Bissig · Duke University · R01 · FY2024 · DK

Capturing the phenotypic landscape of single-nucleotide variation via systematic genome editing

$591,551
Robert St.onge · Stanford University · R01 · FY2017 · GM

Genetics and Pathobiology of Cutaneous Mosaic Disorders

$591,471
Keith A Choate · Yale University · R01 · FY2018 · AR

Molecular Basis of Hereditary Retinal Degenerations

$591,344
Radha Ayyagari · University Of California, San Diego · R01 · FY2018 · EY

Using human iPSC derived microglia and chimeric models to examine the role of PLCG2 in Alzheimers disease

$591,309
Hayk Davtyan · University Of California-Irvine · R01 · FY2018 · AG

A platform to functionally sort and analyze tumor cells within combinatorial metastatic micorenvironments

$591,141
David Kevin Wood · University Of Minnesota · R01 · FY2021 · CA

Mechanisms of Motor Superperformance

$590,870
Juan M. Pascual · Weill Medical Coll Of Cornell Univ · R01 · FY2025 · NS

Heroin-Induced genomic regulation of Ventral Pallidum neuron subtypes

$590,639
David M Dietz · State University Of New York At Buffalo · U01 · FY2023 · DA

Therapeutic strategies for microsatellite expansion diseases using RNA-targeting CRISPR/Cas

$590,464
Eugene Wei-Ming Yeo · University Of California, San Diego · R01 · FY2021 · NS

In Vivo Base Editing for Precision Oncology Models

$590,350
Lukas Edward Dow · Weill Medical Coll Of Cornell Univ · R01 · FY2023 · CA

Targeting Glycogen Metabolism in Ewing's Sarcoma: Diagnostic, Prognostic, and Therapeutic Applications

$590,300
Ramon C. Sun · University Of Florida · R01 · FY2025 · CA

Microgial contribution and therapeutic potential in Friedreich's ataxia

$590,166
Stephanie Cherqui · University Of California, San Diego · R01 · FY2024 · NS

Regulatory Roles and Dynamics of Nuclear long-noncoding RNAs in Pluripotency

$590,084
John Louis Rinn · Harvard University · P01 · FY2018 · GM

Regulatory Roles and Dynamics of Nuclear long-noncoding RNAs in Pluripotency

$590,082
John Louis Rinn · Harvard University · P01 · FY2020 · GM

Convergent Drivers of Tumor Evolution at the Mitotic Spindle

$589,974
Wendy K Rathmell · Vanderbilt University Medical Center · R01 · FY2022 · CA

Regulation of androgen receptor signaling in prostate cancer by protein arginine methylation

$589,812
Srinivas Raghavan Viswanathan · Dana-Farber Cancer Inst · R01 · FY2023 · CA

Identification and analysis of non-coding loci critical for cell viability and chromatin organization

$589,602
Wei Wang · University Of California, San Diego · R01 · FY2025 · HG