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10,766 grants matching checkpoint inhibitor

Targeting STAT3 with Novel Thiomorpholino Antisense Oligonucleotides for Cancer Therapy

$400,000
Xuedong Liu · Vesicle Therapeutics Inc. · R41 · FY2025 · CA

An Aptamer-directed IgG1-Fc Drug Conjugate (AFDC) for Treating Pancreatic Cancer

$400,000
Xiang Gao · Oncotrap, Inc. · R43 · FY2023 · CA

The immunosuppressive function of Checkpoint kinase 2 in gliomas

$400,000
Crismita Clement Dmello · Northwestern University At Chicago · R01 · FY2024 · NS

Development of drug conjugates of R-spondin peptibodies for the treatment of colorectal cancer

$400,000
Jie Cui · Wntrix, Inc. · R41 · FY2023 · CA

Optimization of TIL Cell Manufacturing for Cancer Treatment

$400,000
Soon Seog Jeong · Human Cell Co · R43 · FY2023 · CA

Modulation of cancer induced immune suppression via inhibition of SCD1

$399,986
Karen E Hayes · Modulation Therapeutics, Inc. · R44 · FY2022 · CA

A Novel Melanoma Vaccine Based on a Shared Neoantigen and a Liquid Polymer Platform

$399,979
Chun Wang · Trekka Therapeutics, Llc · R41 · FY2023 · CA

PHASE I AWARD - AN ORGAN-ON-VASCULARNET MODEL FOR IN VITRO EVALUATION OF RADIATION AND DRUG THERAPIES

$399,975
Claude Rogers · Chromologic, Llc · N43 · FY2024 · CA

Developing engineered inhibitors of tRNA modifying enzymes

$399,966
Austin Stratton Draycott · Cloverleaf Bio, Inc. · R42 · FY2025 · CA

CD3 bispecific for the treatment of ROR2-positive NSCLC

$399,955
Jean-Loup Romet-Lemonne · Traverse Biotech Ii Inc · R43 · FY2023 · CA

Automated plasma EV-PDL1 analysis for cancer immunotherapy

$399,913
Liyun Jessica Sang · Accure Health, Inc. · R43 · FY2022 · CA

Development of a salt-based nanomedicine for non-muscle invasive bladder cancer

$399,907
Zhi Liu · Athna Biotech, Inc. · R43 · FY2022 · CA

Human specific STING agonists for the treatment of cancer

$399,812
Glen N Barber · Stinginn, Llc · R41 · FY2023 · CA

Project 1: Glutaminolytic GDH1 activation-dependent immunotherapy resistance in LKB1-mutant lung adenocarcinoma

$399,749
Sumin Kang · Emory University · P01 · FY2024 · CA

Targeting DYRK2 to eradicate leukemia stem cells in chronic myeloid leukemia.

$399,746
H. Daniel Lacorazza · Baylor College Of Medicine · R01 · FY2025 · CA

Engineering a potent locally-acting interleukin 12-expressing synthetic self-replicating mRNA to augment responses to anti-PD-1 therapy in neoadjuvant triple negative breast cancer

$399,725
Tasuku Kitada · Strand Therapeutics Inc · R43 · FY2021 · CA

PLA2G2D Antibodies for Cancer Immunotherapy

$399,618
Li-Fen Lee · Apeximmune Therapeutics Inc. · R43 · FY2023 · CA

Development of Lasso Peptides as Potent Endothelin Receptor B Antagonists for Immuno-oncology

$399,609
Mark J Burk · Lassogen, Inc. · R43 · FY2021 · CA

An innovative telomerase-targeted, circulating tumor cell assay for monitoring NSCLC treated with radiation and immunotherapy

$399,499
Deeksha Saxena · Liquid Biodx Llc · R43 · FY2023 · CA

A novel targeted antibody therapeutic to treat ovarian cancer

$399,478
Reiner Laus · Trio Pharmaceuticals Inc. · R43 · FY2024 · CA

Novel Anti-CCR8 VHH for the Treatment of NSCLC

$399,424
Mauro Mileni · Abilita Bio, Inc. · R43 · FY2023 · CA

ST8Sia6 expression on tumors inhibits the immune response

$399,403
Virginia Smith Shapiro · Mayo Clinic Rochester · R01 · FY2021 · CA

The role of the CD58:CD2 axis in cancer immune evasion and resistance to immunotherapy

$399,379
Benjamin Izar · Columbia University Health Sciences · R01 · FY2023 · CA

Effects of ATR-CHK1 inhibition on genome stability and cancer progression

$399,329
Eric J Brown · University Of Pennsylvania · R01 · FY2016 · CA

Effects of ATR-CHK1 inhibition on genome stability and cancer progression

$399,329
Eric J Brown · University Of Pennsylvania · R01 · FY2017 · CA