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10,766 grants matching checkpoint inhibitor

Targeting CCR2-expressing myeloid cells to overcome immune checkpoint inhibitor resistance in glioma

$378,934
Jeffrey K Harrison · University Of Florida · R01 · FY2021 · NS

Targeting CCR2-expressing myeloid cells to overcome immune checkpoint inhibitor resistance in glioma

$378,934
Jeffrey K Harrison · University Of Florida · R01 · FY2019 · NS

Targeting CCR2-expressing myeloid cells to overcome immune checkpoint inhibitor resistance in glioma

$378,934
Jeffrey K Harrison · University Of Florida · R01 · FY2020 · NS

Applying deep learning to predict T cell receptor binding specificity of neoantigens and response to checkpoint inhibitors

$378,897
Tao Wang · Ut Southwestern Medical Center · R01 · FY2021 · CA

A Pathway for Necrotic Cell Death

$378,867
David J Shapiro · University Of Illinois At Urbana-Champaign · R01 · FY2022 · CA

A Pathway for Necrotic Cell Death

$378,867
David J Shapiro · University Of Illinois At Urbana-Champaign · R01 · FY2023 · CA

Tumor-intrinsic signaling pathways restrict anti-tumor immunity in hepatocellular carcinoma

$378,856
Amaia Lujambio · Icahn School Of Medicine At Mount Sinai · R37 · FY2023 · CA

Regulation of GLI1, a synthetic lethal target of SMARCA4-deficiency, in lung adenocarcinoma

$378,841
James Kim · Ut Southwestern Medical Center · R01 · FY2022 · CA

Project 2: Targeting DNA replication in BRCA-associated breast cancer

$378,763
Bing Xia · Rutgers Biomedical And Health Sciences · P01 · FY2025 · CA

Regulation of the Development of Trypanosoma brucei

$378,750
University Of California San Francisco · R01 · FY2005 · AI

Regulation of the Development of Trypanosoma brucei

$378,750
University Of California San Francisco · R01 · FY2004 · AI

Genetic regulation of genome stability in yeast

$378,690
Thomas D Petes · Duke University · R01 · FY2008 · GM

Genetic regulation of genome stability in yeast

$378,690
Thomas D Petes · Duke University · R01 · FY2009 · GM

Tumor microenvironment-dependent therapy resistance

$378,600
Shahab Asgharzadeh · Children'S Hosp Of Philadelphia · P01 · FY2024 · CA

Targeting heat shock factor 1 (HSF1) to increase tumor infiltrating lymphocytes in metastatic breast cancer.

$378,444
Richard L Carpenter · Indiana University Indianapolis · R01 · FY2025 · CA

Core B: Computational

$378,433
Alan S Perelson · Beth Israel Deaconess Medical Center · P01 · FY2017 · AI

BET protein antagonist-based targeted therapy of Mantle Cell Lymphoma

$378,430
Kapil N. Bhalla · University Of Tx Md Anderson Can Ctr · R01 · FY2019 · CA

Personalized targeting of anti-apoptosis pathways to overcome therapeutic resistance in melanoma

$378,415
Michael Davies · Wistar Institute · U54 · FY2024 · CA

Rare Central Nervous System Cancers Initiative

$378,413
Mark Gilbert · Division Of Basic Sciences - Nci · ZIA · FY2017 · CA

Brain Tumor Immunotherapy

$378,413
Mark Gilbert · Division Of Basic Sciences - Nci · ZIA · FY2017 · CA

Project 1: Targeting immunotherapy-induced resistance with DC vaccination and PD-1/CSF-1R inhibition

$378,369
Robert M Prins · University Of California Los Angeles · P50 · FY2023 · CA

Development and Mechanistic Studies of an Engineered Human Enzyme to Abrogate Immune Suppression due to Elevated Methylthioadenosine (MTA) by MTAP null/low Tumors

$378,348
Everett Stone · University Of Texas At Austin · R01 · FY2021 · CA

Systemic delivery of an oncolytic adenovirus targeting TGFβ to enhance anti-PD-1 and anti-CTLA-4 therapy for triple negative breast cancer

$378,315
Weidong Xu · Endeavor Health Clinical Operations · R01 · FY2023 · CA

The role of ATRX mutation in the epigenetic dysregulation of cell cycle in pediatric high-grade glioma

$378,300
Carl J Koschmann · University Of Michigan At Ann Arbor · R01 · FY2024 · NS

Gene expression signature based screening in Ewing sarcoma

$378,253
David J Gordon · University Of Iowa · R37 · FY2020 · CA