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17,054 grants matching genome editing

Preventing and reversing mitochondrial Leigh syndrome with hypoxia

$537,347
Vamsi Krishna Mootha · Massachusetts General Hospital · R01 · FY2023 · NS

Viscoelastic Properties of Normal and OA Chondrons

$537,335
Farshid Guilak · Washington University · R01 · FY2020 · AG

Enhancing Editing Efficiency, Versatility and Guide Design of CHyMErA Screening Platform

$537,325
Michael Aregger · Division Of Basic Sciences - Nci · ZIA · FY2025 · CA

Evaluation of genetic variants affecting platelet function with CRISPR HDR in human megakaryocytes

$536,992
Jesse Rowley · Utah State Higher Education System--University Of Utah · R01 · FY2025 · HL

Evaluation of genetic variants affecting platelet function with CRISPR HDR in human megakaryocytes

$536,992
Jesse Rowley · University Of Utah · R01 · FY2023 · HL

Disabling the replication-competent HIV provirus in the reservoir by combined CRISPR-Cas action

$536,971
Benjamin Berkhout · Academical Medical Center · R01 · FY2022 · AI

Genetic Analysis of Genes Controlling a Position Effect

$536,915
Jasper D Rine · University Of California Berkeley · R01 · FY2017 · GM

Engineering Human Heart Tissues with Polyploid Cardiomyocytes

$536,797
Nenad Bursac · Duke University · R01 · FY2024 · HL

Retinal Pigmented Epithelium Epigenome Dysregulation With Aging and Modulation by Diet

$536,749
Willard M Freeman · Oklahoma Medical Research Foundation · R01 · FY2025 · EY

Lysosomal Diseases

$536,727
Rosa Puertollano-Moro · National Heart, Lung, And Blood Institute · ZIA · FY2019 · HL

Genetic Determinants of Tumor Growth and Drug Sensitivity in EGFR Mutant Lung Cancer

$536,716
Katerina Abigail Politi · Yale University · R01 · FY2024 · CA

Molecular Mechanisms of Insulin Resistance Associated Loci

$536,612
Thomas None Quertermous · Stanford University · R01 · FY2018 · DK

Editing of the AAT locus using novel base editing and prime editing technologies

$536,581
Wen Xue · Univ Of Massachusetts Med Sch Worcester · P01 · FY2024 · HL

Modulation of Immune responses to gene therapy by Creation of AAV-specific Chimeric antigen receptor regulatory T cells (CAR-Tregs)

$536,581
Allison May Keeler-Klunk · Univ Of Massachusetts Med Sch Worcester · P01 · FY2024 · HL

Impact of Loss-of-function NADPH Oxidase Variants on B cell Activation in SLE

$536,554
Shaun William Jackson · Seattle Children'S Hospital · R01 · FY2021 · AR

Impact of Loss-of-function NADPH Oxidase Variants on B cell Activation in SLE

$536,554
Shaun William Jackson · Seattle Children'S Hospital · R01 · FY2023 · AR

Viscoelastic Properties of Normal and OA Chondrons

$536,421
Farshid Guilak · Washington University · R01 · FY2019 · AG

DEVELOPMENT OF AAV-CRISPR/CAS9-BASED THERAPIES FOR CONE ROD DYSTROPHY

$536,347
Shannon Elizabeth Boye · University Of Florida · R01 · FY2021 · EY

Development of Technologies for Efficient In Vivo Prime Editing

$536,345
Pablo Perez-Pinera · University Of Illinois At Urbana-Champaign · R01 · FY2023 · GM

Development of Technologies for Efficient In Vivo Prime Editing

$536,345
Pablo Perez-Pinera · University Of Illinois At Urbana-Champaign · R01 · FY2022 · GM

Development of Technologies for Efficient In Vivo Prime Editing

$536,345
Pablo Perez-Pinera · University Of Illinois At Urbana-Champaign · R01 · FY2024 · GM

Development and characterization of mouse models of RP59 DHDDS deficiency

$536,290
Steven J Pittler · University Of Alabama At Birmingham · R01 · FY2021 · EY

Behavioral Science Core

$536,191
Alan S Wayne · Division Of Basic Sciences - Nci · ZIC · FY2012 · CA

Development of Technologies for Efficient In Vivo Prime Editing

$535,871
Pablo Perez-Pinera · University Of Illinois At Urbana-Champaign · R01 · FY2021 · GM

Elucidating the molecular basis of piperaquine resistance and the role of altered hemoglobin metabolism in Plasmodium falciparum

$535,760
David Armand Fidock · Columbia University Health Sciences · R01 · FY2017 · AI