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172,184 grants matching “inflammation”
SCH: Develop Clinical Time Series Foundation Models for Sepsis Early Detection
$1,200,000Pengtao Xie · University Of California-San Diego · · FY2024 · CSE
University of Pittsburgh O'Brien Cooperative Research Center Program
$1,200,000Zhou Wang · University Of Pittsburgh At Pittsburgh · U54 · FY2019 · DK
Obesity Enhances Susceptibility to Pollutant Effects in Asthma
$1,200,000Nadia N Hansel · Johns Hopkins University · P50 · FY2017 · ES
Obesity Enhances Susceptibility to Pollutant Effects in Asthma
$1,200,000Nadia N Hansel · Johns Hopkins University · P50 · FY2018 · ES
Stanford O'Brien Urology Research Center
$1,200,000James D Brooks · Stanford University · U54 · FY2021 · DK
University of Pittsburgh O'Brien Cooperative Research Center Program
$1,199,999Zhou Wang · University Of Pittsburgh At Pittsburgh · U54 · FY2020 · DK
Molecular Mechanisms of Asthma
$1,199,935University Of Chicago · P01 · FY2004 · AI
Complement in Cell Proliferation and Injury-Therapeutic Interventions
$1,199,746John D Lambris · University Of Pennsylvania · P01 · FY2007 · AI
Translational Research Center for CAM Therapy of Asthma
$1,199,682University Of North Carolina Chapel Hill · P01 · FY2004 · AT
Translational Research Center for CAM Therapy of Asthma
$1,199,396University Of North Carolina Chapel Hill · P01 · FY2005 · AT
PREVENT Preclinical Drug Development Program: Preclinical Efficacy and Intermediate BiomarkersTask Order Title: Sulforaphane for the Prevention of Malignant Mesothelioma
$1,199,274Joseph Testa · Research Inst Of Fox Chase Can Ctr · N01 · FY2023 · CA
Signaling in the retina and retinal pigment epithelium
$1,199,202Thomas Redmond · National Eye Institute · ZIA · FY2020 · EY
Social epigenetics of Alzheimer's disease and related dementias in Latin American countries
$1,199,134Michael Jay Corley · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · AG
Integrating Structive Activity, Biokinetics and Response for ENP Risk Assessment
$1,199,130Joel G Pounds · Battelle Pacific Northwest Laboratories · U19 · FY2011 · ES
Mechanisms of Chronic Inflammation in Periodontitis
$1,199,034Niki Moutsopoulos · National Institute Of Dental & Craniofacial Research · ZIA · FY2018 · DE
Oral Microbial and Immunological Characterization of Patients with Immune Dysfun
$1,199,034Niki Moutsopoulos · National Institute Of Dental & Craniofacial Research · ZIA · FY2018 · DE
SBIR Phase II: Absolute protein quantitation in in vitro diagnostics for gut inflammation
$1,198,996Robert C Doss · Chosen Diagnostics Inc · · FY2024 · TIP
Cardiovascular Inflammation Reduction Trial (CIRT): DCC
$1,198,942Robert J Glynn · Brigham And Women'S Hospital · U01 · FY2013 · HL
FUTURE MISSIONS IN SPACE (SUCH AS A MISSION TO MARS OR THE ESTABLISHMENT OF A MOON BASE) WILL INVOLVE LONG-TERM TRAVEL BEYOND THE MAGNETIC FIELD OF THE EARTH SUBJECTING ASTRONAUTS TO RADIATION HAZARDS POSED BY SOLAR FLARES AND GALACTIC COSMIC RAYS. COSMIC RAYS ARE COMPOSED OF PROTONS ALPHA PARTICLES AND PARTICLES OF HIGH ENERGY AND CHARGE (HZE PARTICLES). PREVIOUS RESEARCH HAS SHOWN THAT EXPOSURE TO SINGLE ABOVE THRESHOLD DOSES OF HZE PARTICLES AND PROTONS CAN AFFECT NEURAL FUNCTIONING AND BEHAVIOR. THESE CHANGES MAY AFFECT THE ABILITY OF ASTRONAUTS TO SUCCESSFULLY MEET MISSION REQUIREMENTS OR MAY PRODUCE DEGENERATIVE CHANGES IN NEURONAL AND BEHAVIORAL FUNCTIONING AFTER THE CONCLUSION OF THE MISSION. THE EFFECTS OF EXPOSURE TO MULTIPLE SUBTHRESHOLD DOSES OF THE SAME ORDIFFERENT PARTICLES OR PROTONS HAVE NOT BEEN EXTENSIVELY STUDIED. THE OBJECTIVES OF THE PROPOSED RESEARCH PROGRAM ARE: (1) TO EVALUATE THE EFFECTS OF REPEATED SUBTHRESHOLD EXPOSURES TO THE SAME AND DIFFERENT HZE PARTICLES AND PROTONS ON COGNITIVE AND NEURONAL DEFICITS AND HOW THEY RELATE TO THE CHARACTERISTICS OF THE SPECIFIC PARTICLE; (2) TO DETERMINE THE RELATIONSHIP BETWEEN CHANGES IN PERFORMANCEAND HZE PARTICLE- AND PROTON-INDUCED CHANGES IN OXIDATIVE STRESS INFLAMMATION SIGNALING MOLECULES AND AUTOPHAGY IN KEY BRAIN REGIONS; AND (3) TO DETERMINE HOW INDIVIDUAL CHARACTERISTICS INCLUDING AGE AND SEX MAY INFLUENCE THE RESPONSIVENESS OF THE INDIVIDUAL TO HZE PARTICLE IRRADIATION.
$1,198,744University Of Maryland Baltimore County · · FY2016 · National Aeronautics and Space Administration
Environmental and Genetic Risk Factors For Breast Cancer: The Sister Study
$1,198,324Dale P Sandler · National Institute Of Environmental Health Sciences · ZIA · FY2012 · ES
Tissue Injury and Inflammation in Multiple Sclerosis
$1,198,234Richard M Ransohoff · Cleveland Clinic Lerner Com-Cwru · P01 · FY2006 · NS
Innate Immunity in Allergic Airway Inflammation of Asthma
$1,198,111Tony Eissa · Baylor College Of Medicine · U19 · FY2007 · AI
UCSF-Bay Area Center for AIDS Research
$1,197,787Monica Gandhi · University Of California, San Francisco · P30 · FY2022 · AI
Nuclear receptors: action, functions, and roles in disease
$1,197,737Anton M Jetten · National Institute Of Environmental Health Sciences · ZIA · FY2013 · ES
Arthritis and Traditional Chinese Medicine
$1,197,651University Of Maryland Baltimore · P01 · FY2005 · AT