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5,883 grants matching cryo em

Determining the Molecular Basis for HIV-1 Retrograde Trafficking

$773,808
Michael Cianfrocco · University Of Michigan At Ann Arbor · R01 · FY2025 · AI

Mechanism of the transcription factor FoxP3 in regulatory T cell development

$772,604
Sun Hur · Boston Children'S Hospital · R01 · FY2025 · AI

De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity

$772,551
James E Kirby · Beth Israel Deaconess Medical Center · R01 · FY2021 · AI

Exploring the Molecular Physiology of Atrial Fibrillation

$772,293
Steven O Marx · Columbia University Health Sciences · R01 · FY2025 · HL

Exploring the Molecular Physiology of Atrial Fibrillation

$772,293
Steven O Marx · Columbia University Health Sciences · R01 · FY2023 · HL

Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials

$772,231
James E Kirby · Beth Israel Deaconess Medical Center · R01 · FY2022 · AI

HIV-1 membrane fusion and inhibition

$772,175
Bing Chen · Boston Children'S Hospital · R01 · FY2024 · AI

Mechanism of tubulin modification enzymes

$772,127
Antonina Roll-Mecak · National Institute Of Neurological Disorders And Stroke · ZIA · FY2019 · NS

"On the Fly" Time Resolved Cryo-EM Studies of Intermediate HIV-1 RT Transition States

$771,893
Guillermo Alberto Calero · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · AI

"On the Fly" Time Resolved Cryo-EM Studies of Intermediate HIV-1 RT Transition States

$771,893
Guillermo Alberto Calero · University Of Pittsburgh At Pittsburgh · R01 · FY2023 · AI

"On the Fly" Time Resolved Cryo-EM Studies of Intermediate HIV-1 RT Transition States

$771,893
Guillermo Alberto Calero · University Of Pittsburgh At Pittsburgh · R01 · FY2025 · AI

Targeting early metastable intermediates of the SARS-CoV-2 spike for vaccine and therapeutics development

$771,293
Priyamvada Acharya · Duke University · R01 · FY2021 · AI

Structural Basis of Nociceptor Channel TRPM3 gating and pharmacology

$770,832
Juan Du · Van Andel Research Institute · R01 · FY2023 · NS

Structures of initial CD4 engagement with pre-fusion, closed HIV-1 Envelope trimer and early CD4-induced conformational changes required for infection

$770,818
Priyamvada Acharya · Duke University · R01 · FY2023 · AI

Structure-function analysis for elucidating pathogenicity of cardiac ryanodine receptor genetic variants

$770,600
Andrew R Marks · Columbia University Health Sciences · R01 · FY2021 · HL

ARTIFICIAL INTELLIGENCE-ASSISTED INTEGRATIVE BIOMOLECULAR NMR PLATFORM

$768,681
Woonghee Lee · University Of Colorado At Denver · · FY2024 · BIO

Structural analysis of dynamins involved in mitochondrial morphology

$768,052
Jenny E Hinshaw · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2025 · DK

Structure And Function Of Dynamin, A 100kd GTPase Involved In Endocytosis

$768,052
Jenny E Hinshaw · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2025 · DK

Molecular Pharmacology of the Synaptic and Extrasynaptic GABA(A) Receptors

$767,832
Keith W Miller · Massachusetts General Hospital · R01 · FY2020 · GM

Structural Studies of Macromolecular Assemblies Using Cryo-EM

$767,819
Joachim Frank · Columbia University Health Sciences · R35 · FY2025 · GM

Structural Studies of Macromolecular Assemblies Using Cryo-EM

$767,819
Joachim Frank · Columbia University Health Sciences · R35 · FY2024 · GM

Structural Studies of Macromolecular Assemblies Using Cryo-EM

$767,819
Joachim Frank · Columbia University Health Sciences · R35 · FY2023 · GM

Exploring the Molecular Physiology of Atrial Fibrillation

$767,599
Steven O Marx · Columbia University Health Sciences · R01 · FY2022 · HL

Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials

$766,825
James E Kirby · Beth Israel Deaconess Medical Center · R01 · FY2023 · AI

CU Boulder Center for Cryo-ET (CCET)

$766,518
Andreas Hoenger · University Of Colorado · U24 · FY2021 · GM