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5,883 grants matching cryo em

Platelet Integrin AlphaIIbBeta3 Structure, Activation, and Ligand Binding: Fibrinogen, Fibrin, D-dimer, and von Willebrand Factor

$759,040
Barry Coller · Rockefeller University · R01 · FY2023 · HL

Structures of initial CD4 engagement with pre-fusion, closed HIV-1 Envelope trimer and early CD4-induced conformational changes required for infection

$758,709
Priyamvada Acharya · Duke University · R01 · FY2019 · AI

Rare mutations in Cystic Fibrosis: Overcoming barriers to personalized medicine

$758,201
Eric J Sorscher · Emory University · R01 · FY2019 · HL

Transitions: Emergent Microstructures of Protocells

$757,500
Irene Chen · University Of California-Los Angeles · · FY2023 · BIO

Structural interrogation of vaccine- and infection-induced B cell responses

$757,401
Goran Bajic · Icahn School Of Medicine At Mount Sinai · R01 · FY2025 · AI

De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity

$757,156
James E Kirby · Beth Israel Deaconess Medical Center · R01 · FY2023 · AI

Rare mutations in Cystic Fibrosis: Overcoming barriers to personalized medicine

$757,115
Eric J Sorscher · Emory University · R01 · FY2020 · HL

Exploring the Molecular Physiology of Atrial Fibrillation

$756,847
Steven O Marx · Columbia University Health Sciences · R01 · FY2024 · HL

Epitope and mechanistic correlates of broadly protective human antibodies for pneumococcal infection

$755,894
Jarrod Mousa · University Of Georgia · R01 · FY2023 · AI

Platelet alphaIIbbeta3 activation and its therapeutic targeting

$754,451
M. Amin Arnaout · Massachusetts General Hospital · R01 · FY2025 · HL

Roles of HIV-1 capsid-binding FG-motif containing cellular cofactors in infection

$753,963
Mamuka Kvaratskhelia · University Of Colorado Denver · R01 · FY2025 · AI

HIV-1 membrane fusion and inhibition

$752,675
Bing Chen · Boston Children'S Hospital · R01 · FY2025 · AI

STRUCTURAL STUDIES ON ROTAVIRUS

$752,646
Bidadi V Venkataram Prasad · Baylor College Of Medicine · R01 · FY2025 · AI

Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution

$752,496
Edward H. Egelman · University Of Virginia · R35 · FY2025 · GM

Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution

$752,496
Edward H. Egelman · University Of Virginia · R35 · FY2024 · GM

Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution

$752,496
Edward H. Egelman · University Of Virginia · R35 · FY2023 · GM

Structural Studies of Human Papillomavirus

$751,536
Susan Hafenstein · Pennsylvania State Univ Hershey Med Ctr · R01 · FY2022 · AI

Probing the Biochemical Mechanisms of Amyloid Disease

$751,514
Jeffery W Kelly · Scripps Research Institute, The · R01 · FY2016 · DK

Enrichment of the State-1 Conformation of the HIV-1 Envelope Glycoprotein

$750,826
Joseph G Sodroski · Dana-Farber Cancer Inst · R01 · FY2021 · AI

Structural analysis of tau associated with parenchymal and vascular prion protein amyloidosis

$750,707
Ruben Vidal · Indiana University Indianapolis · R01 · FY2024 · AG

Small molecule inhibitors targeting the ribosome binding site of ricin and Shiga toxin

$750,137
Nilgun E Tumer · Rutgers, The State Univ Of N.J. · R01 · FY2024 · AI

Transition To Excellence: From Single-Molecule Force Spectroscopy to Single-Particle Cryogenic Electron Microscopy

$750,000
Piotr E Marszalek · Duke University · · FY2021 · BIO

High Performance Computing Cluster for Biomedical Research at VCU

$749,998
Preetam Ghosh · Virginia Commonwealth University · S10 · FY2025 · OD

Illuminating the Druggable GPCR-ome

$749,510
Bryan L Roth · Univ Of North Carolina Chapel Hill · U24 · FY2022 · DK

Bactericidal antibiotics targeting lipoprotein transport in Gram-negative bacteria

$749,417
Andrew G Myers · Harvard University · R01 · FY2025 · AI