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10,766 grants matching checkpoint inhibitor

Defining the features of T cell response to tumor and self-antigens as predictors of response to checkpoint therapy

$946,097
Jane Hoyt Buckner · Benaroya Research Inst At Virginia Mason · R01 · FY2020 · CA

Interrogating the Evolutionary Dynamics of Cancer for Clinical Benefit and Actionability

$944,561
Christine A Iacobuzio-Donahue · Sloan-Kettering Inst Can Research · R35 · FY2020 · CA

Spherical Nucleic Acid nano-architectures as first-in-class cGAS agonists for the immunotherapeutic treatment of Glioblastoma.

$943,101
Alexander H. Stegh · Washington University · R01 · FY2025 · CA

A Rational Systematic Approach to Find Combinations of Pharmacologic and Immune Therapies that Target Identifiable Oncogenic States

$942,132
Pablo Tamayo · University Of California, San Diego · U01 · FY2021 · CA

Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis

$941,397
Don W. Cleveland · University Of California, San Diego · R35 · FY2022 · GM

Promoting Kidney Transplantation Tolerance Through Novel Immunomodulation and Cellular Therapy

$939,602
Andrew B Adams · University Of Minnesota · U19 · FY2024 · AI

Deciphering the crosstalk between bacteria and their mammalian hosts

$939,000
Aaron Thomas Whiteley · University Of Colorado · DP2 · FY2025 · AT

Wee1 and HDAC inhibition in relapsed/refractory AML

$938,670
Steven Grant · Virginia Commonwealth University · UH2 · FY2015 · TR

Clinical Evaluation of a Personalized Vaccine Immunotherapy in Combination with Checkpoint Inhibitors for Triple Negative Breast Cancer

$938,597
Christopher D Pack · Metaclipse Therapeutics Corporation · R44 · FY2022 · CA

Molecular Pathogenesis of Neoplasia

$937,516
Richard Youle · National Institute Of Neurological Disorders And Stroke · ZIA · FY2019 · NS

Next Generation Cancer Immunotherapies to Defeat Melanoma

$936,000
Antoni Ribas · University Of California Los Angeles · R35 · FY2025 · CA

Next Generation Cancer Immunotherapies to Defeat Melanoma

$936,000
Antoni Ribas · University Of California Los Angeles · R35 · FY2022 · CA

Promoting Kidney Transplantation Tolerance Through Novel Immunomodulation and Cellular Therapy

$935,944
Andrew B Adams · University Of Minnesota · U19 · FY2023 · AI

Radiation-induced translational control of gene expression

$935,346
Philip Tofilon · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA

Metabolic reprogramming of the tumor microenvironment and therapy resistance

$934,799
Ernst Lengyel · University Of Chicago · R35 · FY2024 · CA

Oncolytic Polovirus, Immunotoxin, and Checkpoint Inhibitor Therapy of Gliomas

$933,896
Darell D Bigner · Duke University · R35 · FY2016 · CA

Novel Nano-immunotherapy for Treatment of Non-small Cell Lung Cancer

$932,751
Worapol Ngamcherdtrakul · Pdx Pharmaceuticals, Inc. · R44 · FY2024 · CA

Novel Nano-immunotherapy for Treatment of Non-small Cell Lung Cancer

$932,751
Worapol Ngamcherdtrakul · Pdx Pharmaceuticals, Inc. · R44 · FY2023 · CA

Systems genetics analysis of tumor evolution in the mouse

$931,980
Allan Balmain · University Of California, San Francisco · R35 · FY2022 · CA

Systems genetics analysis of tumor evolution in the mouse

$931,980
Allan Balmain · University Of California, San Francisco · R35 · FY2023 · CA

Strategies for improving early detection, diagnosis and treatment of liver cancer

$930,599
Xin Wei Wang · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Understanding and Exploiting Loss of Y in Cancer

$930,500
Dan Theodorescu · University Of Arizona · R35 · FY2025 · CA

The Evaluation of Novel Therapeutics for Genitourinary Malignancies

$929,563
William Laurence Dahut · Division Of Clinical Sciences - Nci · ZIA · FY2016 · CA

Initiation of DNA replication in Mammalian Cells

$926,998
Mirit Aladjem · Basic Sciences · Z01 · FY2007 · CA

Maximizing the Effectiveness of PI3K Inhibitors in the Treatment of Pten null Cancers

$925,398
Thomas M Roberts · Dana-Farber Cancer Inst · R35 · FY2019 · CA