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48,453 grants matching “machine learning”
Open data-driven infrastructure for building biomolecular force fields for predictive biophysics and drug design
$608,856Michael R Shirts · University Of Colorado · R01 · FY2021 · GM
Develop a wireless, skin-conformable and dual-sensing wearable system in support of voice and upper airway telehealth care
$608,826Wei Gao · California Institute Of Technology · R01 · FY2024 · DC
Using Machine Learning to find a life saving needle in a haystack of children's emergencies
$608,819Jeanne-Marie Guise · Beth Israel Deaconess Medical Center · R01 · FY2023 · HL
Reconstruction-free three dimensional positron emission imaging
$608,769Sun Il Kwon · University Of California At Davis · R01 · FY2024 · EB
POINT of CARE: PrOviding an Innovative New Triage and Treatment strategy for Cervical cAncer scReening Efficiency
$608,735Rachel Masch · Basic Health International, Inc. · R01 · FY2025 · CA
A multifaceted adaptive mobile application to promote self-management and improve outcomes in heart failure
$608,732Michael Dorsch · University Of Michigan At Ann Arbor · R01 · FY2022 · AG
Validity and Utility of Consumer-based Wearable Fitness Trackers to Monitor Free-Living Physical Activity Energy Expenditure and Sleep in Children 5-12 Years Old
$608,716Robert G Weaver · University Of South Carolina At Columbia · R01 · FY2024 · DK
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** UNDERSTANDING MICROBIOME STRUCTURE IN AGRIFOOD SYSTEMS IS CRITICAL IN HARNESSING THIS VITAL ECOSYSTEM TO PROMOTE CROP GROWTH AND CLIMATE RESILIENCE WHILE MITIGATING PLANT AND ZOONOTIC PATHOGENS AND DISEASES. UBIQUITOUS APPLICATIONS OF NANOMATERIALS (NMS) RAISE CONCERNS ABOUT THEIR IMPACTS ON MICROBIOME STRUCTURE AND PATHOGEN PERSISTENCE IN SOIL AND IRRIGATION WATER. IN THIS PROPOSAL, WE WILL ATTEMPT TO ADDRESS THIS CRITICAL KNOWLEDGE GAP USING A STATE-OF-THE-ART MULTI OMICS AND MACHINE LEARNING (ML) PLATFORM. TWENTY TYPES OF MONODISPERSE NMS WILL BE SYNTHESIZED AND CHARACTERIZED. WE WILL INVESTIGATE HOW NMS ALTER MICROBIOME STRUCTURE IN SOIL AND WATER BY NANOPORE 16S AND 18S RRNA SEQUENCING. ADDITIONAL STUDIES WILL FOCUS ON THE NMS CAUSING THE MOST SIGNIFICANT CHANGES IN PATHOGEN PERSISTENCE. MECHANISM OF NMS-INDUCED PATHOGEN EVOLUTION AND ADAPTION WILL BE REVEALED USING MULTI-OMICS AND ML, INVOLVING NANOPORE WHOLE GENOME SEQUENCING (WGS), WHOLE TRANSCRIPTOME SEQUENCING (WTS), AND METABOLOMICS. ALL EXPERIMENTS WILL INCLUDE CLIMATE SIMULATION TO EXAMINE WHETHER CLIMATE CHANGE AGGRAVATES NMS' RISKS AND IMPLICATIONS IN AGRIFOOD SYSTEMS. THE OUTCOME AND SIGNIFICANCE OF THE STUDY ARE MULTIFACETED. REVEALING DETRIMENTAL EFFECTS WOULD DEMAND RESPONSIBLE INNOVATION IN AGRIFOOD NANOTECHNOLOGY, WHICH MAY REQUIRE BETTER PRACTICES, POLICIES, OR END-OF-LIFE TREATMENT AND RISK MITIGATION. BENEFICIAL EVIDENCE, HOWEVER, WOULD VALIDATE NANOTECHNOLOGY AS THE PROMISING LEVERAGE TO HARNESS THE MICROBIOME FOR FOOD SAFETY AND SECURITY WITH CLIMATE RESILIENCE.
$608,676University Of Florida · · FY2023 · National Institute of Food and Agriculture
RET Site: Research Experiences for Teachers in Biologically-inspired Computing Systems
$608,628Na Gong · University Of South Alabama · · FY2020 · CSE
Novel Biomarker to Identify Critical Windows of Susceptibility to Metal Mixture
$608,605Manish Arora · Icahn School Of Medicine At Mount Sinai · R01 · FY2019 · ES
Assessing and improving the resilience of bioinformatics pipelines to data errors
$608,586Mihai Pop · Univ Of Maryland, College Park · R01 · FY2025 · LM
Harnessing the Host Response to Leptosporisis for Diagnosis and Prognosis
$608,557Megan Elizabeth Reller · University Of California Los Angeles · P01 · FY2024 · AI
Evaluation of artificial intelligence-controlled CPR to improve vital organ perfusion and survival during prolonged resuscitation
$608,552Demetris Yannopoulos · University Of Minnesota · R01 · FY2021 · HL
Genetic and Genomic Dissection of Psoriatic Arthritis
$608,486James Tilford Elder · University Of Michigan At Ann Arbor · R01 · FY2021 · AR
Development and validation of a novel point-of-care technology for rapid non-targeted identification of emerging opioid and other drug threats
$608,483Daniel M Werb · University Of California, San Diego · UG1 · FY2025 · DA
Deriving high-quality evidence from national healthcare databases to improve suicidality detection and treatment outcomes in PTSD
$608,473Christophe G. Lambert · University Of New Mexico Health Scis Ctr · R01 · FY2025 · MH
Novel PET/MR Imaging Approach for Persistent Postsurgical Pain Following Joint Replacement
$608,405Sandip Biswal · Stanford University · R01 · FY2022 · AR
Machine learning with immunogenetics for the prediction of hematopoietic cell transplant outcomes
$608,405Katharine C Hsu · Sloan-Kettering Inst Can Research · R01 · FY2022 · HL
Reverse Sensitivity Analysis for Identifying Predictive Proteomics Signatures of Cancer
$608,348H. Steven Wiley · Battelle Pacific Northwest Laboratories · U01 · FY2019 · CA
Data Management and Statistical Core
$608,285Ali Shojaie · University Of Washington · P30 · FY2025 · AG
Technology and Data Science Core
$608,242Daryush Dinyar Mehta · Massachusetts General Hospital · P50 · FY2024 · DC
Integrate Dynamic System Model and Machine Learning for Calibration-Free Noninvasive ICP
$608,229Xiao Hu · University Of California, San Francisco · R01 · FY2019 · NS
SOCRATES: SOCial Risk and diAbetes ouTcomEs Study
$608,162Seth A Berkowitz · Univ Of North Carolina Chapel Hill · R01 · FY2022 · DK
Biomedical Informatics Tools for Applied Perioperative Physiology
$608,137Maxime Cannesson · University Of California Los Angeles · R01 · FY2023 · EB
Natural Language Processing Techniques To Enhance Information Access.
$608,137Willy Wilbur · National Library Of Medicine · ZIA · FY2009 · LM