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10,766 grants matching checkpoint inhibitor

Impact of Leukemia Microenvironment on Response to Targeted Therapies in AML

$727,832
Anupriya Agarwal · Oregon Health & Science University · U54 · FY2017 · CA

Understanding Early Drivers and Therapeutic Targets for Severe Forms of Arrhythmogenic Cardiomyopathy

$727,710
Farah Sheikh · University Of California, San Diego · R01 · FY2025 · HL

T cells in the aging brain

$727,495
Anne Brunet · Stanford University · R01 · FY2023 · AG

Harnessing double stranded-RNA (dsRNA)-response and anti-tumor effect in PRC2-inactivated cancer

$727,224
Ping Chi · Sloan-Kettering Inst Can Research · R01 · FY2025 · CA

Targeting Protein Arginine Methyltransferases to Eradicate Acute Myeloid Leukemia

$727,057
Ling Li · Beckman Research Institute/City Of Hope · R01 · FY2024 · CA

Radiation-induced translational control of gene expression

$726,840
Philip Tofilon · Division Of Basic Sciences - Nci · ZIA · FY2018 · CA

Mechanisms driving acute and chronic kidney function decline after immune checkpoint inhibitor therapy for cancer

$726,788
Meghan E. Sise · Massachusetts General Hospital · R01 · FY2022 · DK

T cells in the aging brain

$726,768
Anne Brunet · Stanford University · R01 · FY2024 · AG

Targeting novel therapeutic vulnerabilities in LKB1 mutant tumors.

$726,766
Nabeel Bardeesy · Massachusetts General Hospital · R01 · FY2018 · CA

Mechanisms driving acute and chronic kidney function decline after immune checkpoint inhibitor therapy for cancer

$726,628
Meghan E. Sise · Massachusetts General Hospital · R01 · FY2023 · DK

Leveraging fructose transport to create a privileged substrate to selectively fuel T cells

$726,151
Kayvan R Keshari · Sloan-Kettering Inst Can Research · R01 · FY2021 · CA

The Thromboxane-Prostanoid Receptor in Radiation-Induced Pulmonary Fibrosis

$725,891
James D West · Vanderbilt University Medical Center · R01 · FY2023 · CA

The Thromboxane-Prostanoid Receptor in Radiation-Induced Pulmonary Fibrosis

$725,891
James D West · Vanderbilt University Medical Center · R01 · FY2025 · CA

PROJECT 2: Development and Refinement of Predictive Models for Designing Immunotherapy Combination Treatments

$725,549
Vesteinn Thorsson · Institute For Systems Biology · U54 · FY2023 · CA

Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitors

$725,319
Michael Karin · University Of California, San Diego · U01 · FY2021 · AA

Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitors

$725,319
Michael Karin · University Of California, San Diego · U01 · FY2022 · AA

Identification of genetic interactors of Brca2

$725,148
Shyam Sharan · Division Of Basic Sciences - Nci · ZIA · FY2016 · CA

Immune Response to RBC Antigens

$724,646
Krystalyn E Hudson · Columbia University Health Sciences · R01 · FY2023 · HL

Activating Cell Death Pathways in Breast Cancer Cells

$724,562
Stanley Lipkowitz · Division Of Clinical Sciences - Nci · ZIA · FY2019 · CA

Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitors

$724,384
Michael Karin · University Of California, San Diego · U01 · FY2020 · AA

Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitors

$724,197
Michael Karin · University Of California, San Diego · U01 · FY2019 · AA

Detection of PD-1 inhibitory signaling and its molecular relays in T cells: Implications for cancer immunotherapy

$722,621
Vassiliki A Boussiotis · Beth Israel Deaconess Medical Center · R01 · FY2023 · CA

Attacking the Tumor Cell-Immune Milieu Interface to Overcome Richter's Transformation

$721,723
Lili Wang · Beckman Research Institute/City Of Hope · R01 · FY2025 · CA

Mechanisms of cancer immunotherapy-associated thrombosis

$721,398
Keith R. McCrae · Cleveland Clinic Lerner Com-Cwru · R01 · FY2023 · HL

Regulation and Function of WIP1 Phosphatase and its Role in Tumor Cells

$721,121
Ettore Appella · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA