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24,576 grants matching “microbiome”
Regulation of human dendritic cell activation
$303,522Giorgio Trinchieri · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA
Metagenomic Studies of the Gut Microbiomes of Obese and Lean Twins
$303,412Jeffrey Ivan Gordon · Washington University · P01 · FY2013 · DK
Translational Basic and Clinical Research Training in Rheumatology
$303,342Jill P Buyon · New York University School Of Medicine · T32 · FY2020 · AR
Lung Health Study in the Agricultural Health Study
$303,326Stephanie London · National Institute Of Environmental Health Sciences · ZIA · FY2017 · ES
Engineering a Small Intestinal Microbiome to Evaluate Food Additive Exposure
$303,320Gretchen Mahler · State University Of Ny,Binghamton · R01 · FY2021 · ES
Stroke Central Atlantic Network for Research (SCANR)
$303,296Barbara S Bregman · Medstar Health Research Institute · U24 · FY2021 · NS
Statistical Methods for Next-Generation Sequence Data
$303,282Hongzhe Lee · University Of Pennsylvania · R01 · FY2015 · GM
Functional differentiation of tsetse species microbiota
$303,244Rita V M Rio · West Virginia University · R01 · FY2016 · AI
Molecular mechanisms of histone modification - Alzheimerâs supplement NOT-AG-18-008
$303,239John M Denu · University Of Wisconsin-Madison · R37 · FY2018 · GM
Gnotobiotic Animal Core
$303,048Ryan Balfour Sartor · Univ Of North Carolina Chapel Hill · P30 · FY2025 · DK
Biologic Specimen Bank for Early Lung Cancer Markers
$303,027Christian Abnet · Division Of Cancer Epidemiology And Genetics · ZIA · FY2018 · CA
Role of Gut Bacterial Side-Chain Cleavage of Cortisol in Host 11Beta-Hydroxyandrostenedione Formation
$302,965Jason Michael Ridlon · University Of Illinois At Urbana-Champaign · R01 · FY2023 · GM
Engineering a Small Intestinal Microbiome to Evaluate Food Additive Exposure
$302,964Gretchen Mahler · State University Of Ny,Binghamton · R01 · FY2022 · ES
Non-Invasive Single-Cell Morphometry and Tracking in Living Bacterial Biofilms
$302,927Andreas Gahlmann · University Of Virginia · R01 · FY2020 · GM
Defining CRISPR adaptation and interference mechanisms in E. coli
$302,912Dipali Gurudutt Sashital · Iowa State University · R01 · FY2018 · GM
**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** OBESITY IS A CHRONIC PROGRESSIVE DISEASE THAT LEADS TO THE DEVELOPMENT OF TYPE 2 DIABETES, HEART DISEASE, AND STROKE, ALL OF WHICH ARE AMONG THE TOP 10 LEADING CAUSES OF DEATH IN THE U.S. CURRENTLY, LIFESTYLE MODIFICATION, INCLUDING DIET, EXERCISE, AND BEHAVIOR THERAPY, HAS REMAINED THE FIRST OPTION TO EFFECTIVELY AND SAFELY CONTROL THE PROGRESSION OF OBESITY AND OBESITY-RELATED DISEASES. HOWEVER, LOW ADHERENCE TO LIFESTYLE INTERVENTIONS UNDERSCORES THE URGENCY TO DEVELOP OTHER STRATEGIES TO COMBAT OBESITY. WE ARE THE FIRST RESEARCH GROUP TO INVESTIGATE THE NUTRACEUTICAL VALUES OF DIETARY EXOSOME-LIKE NANOPARTICLES (ELNS) IN OBESITY. WE FOUND THAT CHIVE-DERIVED ELNS (C-ELNS) IMPROVE METABOLIC HEALTH IN DIET-INDUCED OBESE MICE. CONTINUING ALONG THIS LINE OF RESEARCH, IN THIS PROJECT WE WILL INVESTIGATE (1) THE BIOAVAILABILITY AND DISTRIBUTION OF C-ELNS IN VIVO; (2) ABSORPTION OF C-ELNS IN INTESTINAL EPITHELIAL CELLS; AND (3) THE IMPACT OF C-ELNS ON THE GUT MICROBIOME IN OBESITY. SUCCESSFUL COMPLETION OF THE PROPOSED RESEARCH WILL PROVIDE MECHANISTIC INSIGHTS INTO HOW C-ELNS DISTRIBUTE AND FUNCTION IN VIVO AND PAVE THE WAY FOR APPLYING C-ELNS TO COMBAT OBESITY.
$302,904Board Of Regents Of The University Of Nebraska · · FY2021 · National Institute of Food and Agriculture
Cross Repository Metabolomics Data and Workflow Integration
$302,764Pieter C Dorrestein · University Of California, San Diego · R03 · FY2022 · OD
Institutional Training Grant in Pediatric Gastroenterology
$302,701Ronald J Sokol · University Of Colorado Denver · T32 · FY2020 · DK
Modeling Emergent Behaviors in Systems Biology: A Biological Physics Approach
$302,664Pankaj Mehta · Boston University (Charles River Campus) · R35 · FY2016 · GM
Role of Innate Immunity and Microbiome in the Inflammation of Aging and Long-Term Antiretroviral Therapy
$302,596Namita Rout · Tulane University Of Louisiana · P20 · FY2020 · GM
Role of Gut Bacterial Side-Chain Cleavage of Cortisol in Host 11Beta-Hydroxyandrostenedione Formation
$302,497Jason Michael Ridlon · University Of Illinois At Urbana-Champaign · R01 · FY2022 · GM
Advanced Statistical Methods for Microbiome Data Analysis
$302,422Zhengzheng Tang · University Of Wisconsin-Madison · R01 · FY2020 · GM
Data Processing and Analysis Core
$302,408Arpana Church · University Of California Los Angeles · U54 · FY2022 · DK
Defining CRISPR adaptation and interference mechanisms in E. coli
$302,344Dipali Gurudutt Sashital · Iowa State University · R01 · FY2017 · GM
Administrative Core: Interventions to improve alcohol-related comorbidities along the gut-brain axis in persons with HIV infection
$302,263Robert L Cook · University Of Florida · P01 · FY2021 · AA