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24,576 grants matching “microbiome”
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** THE PROPOSED PROJECT AIMS TO ENHANCE THE SUSTAINABILITY OF COTTON PRODUCTION BY INVESTIGATING THE IMPACT OF COVER CROPS ON THE SOIL MICROBIOME AND ITS SUBSEQUENT EFFECTS ON COTTON DEVELOPMENT. THE PROJECT SEEKS TO ACHIEVE TWO MAIN OBJECTIVES: 1) INVESTIGATE THE EFFECT OF COVER CROP SPECIES ON SOIL MICROBIAL COMMUNITY STRUCTURE AND FUNCTION, AND 2) EXAMINE THE INFLUENCE OF DIFFERENT COVER CROP SPECIES ON COTTON ROOT DEVELOPMENT AND WATER- AND NUTRIENT-UPTAKE. SOILS IN THE SOUTHEASTERN UNITED STATES ARE SEVERELY DEGRADED, AND METHODS TO IMPROVE SOIL HEALTH TO ARE CRITICAL TO ENSURE SUSTAINABLE CROP PRODUCTION FOR THE FUTURE. EXISTING KNOWLEDGE SHOWS THAT COVER CROPS CAN INCREASE SOIL ORGANIC CARBON STORAGE, IMPROVE SOIL FERTILITY, AND ENHANCE SOIL STRUCTURE. HOWEVER, THE INFLUENCE OF COVER CROPS ON SOIL MICROBIAL COMMUNITIES AND THEIR ROLE IN COTTON DEVELOPMENT IS LESS UNDERSTOOD. THROUGH FIELD EXPERIMENTS AND SUBSEQUENT SOIL AND PLANT SAMPLE ANALYSES, THIS PROJECT WILL ASSESS THE ABUNDANCE AND FUNCTIONALITY OF MICROBIAL COMMUNITIES IN DIFFERENT COVER CROP TREATMENTS. THIS WILL INCLUDE MEASURING MICROBIAL BIOMASS, ARBUSCULAR MYCORRHIZAL FUNGI COLONIZATION, AND AMPLICON SEQUENCING TO ANALYZE SOIL BACTERIAL AND ARCHAEAL COMMUNITIES. ADDITIONALLY, PHYSIOLOGICAL MEASUREMENTS OF COTTON, INCLUDING PHOTOSYNTHESIS, TRANSPIRATION, WATER USE EFFICIENCY, LEAF AREA INDEX, AND NUTRIENT UPTAKE, WILL BE PERFORMED, AND COTTON ROOT CHARACTERISTICS WILL BE MEASURED. THE PROJECT ADDRESSES THE AFRI COMMODITY BOARD CO-FUNDING TOPIC TO DEVELOP APPROACHES TO ENHANCE THE MICROBIOME IN COTTON PRODUCTION BY PROVIDING INSIGHTS INTO COVER CROP INFLUENCE ON THE SOIL MICROBIOME, LEADING TO A BETTER UNDERSTANDING OF SOIL HEALTH AND IMPACTS ON COTTON PERFORMANCE.
$294,000Auburn University · · FY2024 · National Institute of Food and Agriculture
A Mucus-producing Intestinal Epithelium Model for In Vitro Drug Absorption Testing
$293,991Bill Thelin · Altis Biosystems, Inc. · R43 · FY2022 · DK
Intestinal Mucosal Immune and Functional Response to Gastric and Enteric Pathogen
$293,928Alessio Fasano · University Of Maryland Baltimore · U19 · FY2010 · AI
Integrated Genomics Shared Resource
$293,916Martina L Veigl · Case Western Reserve University · P30 · FY2020 · CA
Effect of anti-IL4Ra on the Host-Microbe Interface in Atopic Dermatitis
$293,873Lisa Ann Beck · National Jewish Health · U19 · FY2017 · AI
Microbiome Meta-Analysis Platform
$293,790Mansur R. Kabuka · Infotech Soft, Inc. · R44 · FY2020 · GM
Center for Accelerating Precision Pain Self-Management
$293,710Angela Renee Starkweather · University Of Connecticut Storrs · P20 · FY2020 · NR
Laboratory Sciences Core (Core D)
$293,700Spyros A Kalams · Vanderbilt University Medical Center · P30 · FY2020 · AI
Role of Gut Bacterial Side-Chain Cleavage of Cortisol in Host 11Beta-Hydroxyandrostenedione Formation
$293,589Jason Michael Ridlon · University Of Illinois At Urbana-Champaign · R01 · FY2020 · GM
Role of Gut Bacterial Side-Chain Cleavage of Cortisol in Host 11Beta-Hydroxyandrostenedione Formation
$293,589Jason Michael Ridlon · University Of Illinois At Urbana-Champaign · R01 · FY2021 · GM
Training Program in Investigative Rheumatology
$293,584Richard J Bucala · Yale University · T32 · FY2025 · AR
Characterizing Exposures and Outcomes in an Urban Birth Cohort (CHERUB)
$293,474Dana Boyd Barr · Emory University · P50 · FY2015 · ES
(8) Mechanisms of autoimmune endocrine diseases in patients receiving checkpoint inhibitors
$293,469Kevan C Herold · Yale University · R01 · FY2018 · CA
Biomedical Resource Core
$293,347Paul A Welling · Johns Hopkins University · U54 · FY2025 · DK
Integrated Genomics Shared Resource
$293,312Martina L Veigl · Case Western Reserve University · P30 · FY2021 · CA
Statistical Methods for Next-Generation Sequence Data
$293,302Hongzhe Lee · University Of Pennsylvania · R01 · FY2013 · GM
Investigation on Oligosaccharides as Antimicrobial and Prebiotics
$293,240Peng George Wang · Georgia State University · R01 · FY2013 · HD
Gut Microbiome in Adults with Early Life Exposures to Environmental Chemicals
$293,034Philippe Adam Grandjean · Harvard School Of Public Health · R21 · FY2014 · ES
FLORIDA IS THE LARGEST CITRUS PRODUCER IN THE U.S., BUT THE CITRUS INDUSTRY RELIES ON THE APPLICATION OF MEDICALLY IMPORTANT ANTIBIOTICS TO CONTROL CITRUS GREENING DISEASE, WHICH HAS REDUCED FLORIDA CITRUS PRODUCTION BY 70%. THE IMPACTS OF ANTIBIOTICS ON ANTIMICROBIAL RESISTANCE BACTERIA (ARB) AND PLANT HEALTH LACKS ATTENTION. WE HYPOTHESIZE THAT ANTIBIOTIC APPLICATIONS INCREASE FREQUENCIES OF ARB, COMPROMISE PLANT HEALTH, AND ALTER THE ROOT-ASSOCIATED MICROBIOME, LEADING TO LOSS OF IMPORTANT ECOLOGICAL BACTERIA WITH PLANT HEALTH FUNCTIONS. OVERALL PROJECT GOALS ARE TO DEVELOP FOUNDATIONAL KNOWLEDGE AND AN APPLIED SUSTAINABLE APPROACH TO MITIGATE ARB ASSOCIATED WITH FRESH PRODUCE, WHILE INCREASING PLANT HEALTH, AND TO EDUCATE CURRENT AND FUTURE CONSUMERS AND MICROBIOLOGISTS. OUR OBJECTIVES ARE TO: ASSESS THE IMPACT OF ANTIBIOTICS ON ARB FREQUENCIES, PLANT PHYSIOLOGY, METABOLITES, AND MICROBIOME OF CITRUS TREES; DETERMINE THE EFFECTS OF PROBIOTIC SUPPLEMENTATION ON PLANT HEALTH AND ARB; AND EDUCATE UNDERGRADUATE STUDENTS AND SECONDARY SCHOOL TEACHERS ON ANTIMICROBIAL RESISTANCE (AMR) ACROSS THE FOOD CHAIN AND STRATEGIES FOR MITIGATING AMR.
$292,979University Of Florida · · FY2022 · National Institute of Food and Agriculture
NICHD Cooperative Multicenter Neonatal Research Network
$292,971Kurt R Schibler · Cincinnati Childrens Hosp Med Ctr · U10 · FY2014 · HD
Synthesis and function of Queuosine in Bacteria
$292,958Valerie De Crecy-Lagard · University Of Florida · R01 · FY2022 · GM
The Role of CD4+ Memory Phenotype, Memory, and Effector T Cells in Vaccination
$292,855Mark M Davis · Stanford University · U19 · FY2015 · AI
Strategies and Therapies for Outcomes Prevention in Cirrhosis: The STOP-C Liver Cirrhosis Network
$292,750Robert S Brown · Weill Medical Coll Of Cornell Univ · U01 · FY2024 · DK
Translational Basic and Clinical Research Training in Rheumatology
$292,700Jill P Buyon · New York University School Of Medicine · T32 · FY2018 · AR
Fast Forwarding Women's Reproductive Health Research: University of Michigan WRHR Career Development Program
$292,561Timothy Rb Johnson · University Of Michigan At Ann Arbor · K12 · FY2016 · HD