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24,576 grants matching “microbiome”
Cobalamin serves as a key redox-active mediator, protecting Porphyromonas gingivalis from oxidative stress.
$273,875Shirin Ghods · University Of Louisville · P20 · FY2025 · GM
The role of sugar transport in C. difficile colonization and disease
$273,875James Tristan Collins · University Of Louisville · P20 · FY2023 · GM
Edible Plant-derived exosome-like nanoparticles (ELNs) and phage inhibit brain inflammation by targeting microglia and gut microbiota
$273,875Yun Teng · University Of Louisville · P20 · FY2023 · GM
The role of sugar transport in C. difficile colonization and disease
$273,875James Tristan Collins · University Of Louisville · P20 · FY2025 · GM
Training in Mechanisms of Parasitism
$273,875Mary Edythe Wilson · University Of Iowa · T32 · FY2016 · AI
Regulation of LPS structure and function in Porphyromonas gingivalis
$273,875Fata Moradali · University Of Louisville · P20 · FY2023 · GM
The role of sugar transport in C. difficile colonization and disease
$273,874James Tristan Collins · University Of Louisville · P20 · FY2024 · GM
Edible Plant-derived exosome-like nanoparticles (ELNs) and phage inhibit brain inflammation by targeting microglia and gut microbiota
$273,873Yun Teng · University Of Louisville · P20 · FY2024 · GM
Omics and Symptom Science Training Program
$273,656Margaret McLean Heitkemper · University Of Washington · T32 · FY2019 · NR
Staphylococcal Biofilms in Allergic Disease
$273,654Andrew B Herr · Cincinnati Childrens Hosp Med Ctr · U19 · FY2019 · AI
Innate immunity and alteration of oral microbiome in SIV infected rhesus macaque
$273,539Michael D. George · University Of California At Davis · R21 · FY2010 · DE
Duke University Medical Center (DUMC) Pelvic Floor Disorders Network (PFDN) Clinical Site
$273,496Nazema Y Siddiqui · Duke University · UG1 · FY2022 · HD
Studying Human Gut Microbiome for Osteoporosis Risk
$273,486Hui Shen · Tulane University Of Louisiana · U19 · FY2025 · AG
Administrative Core
$273,365Cathy L Mendelsohn · Columbia University Health Sciences · U54 · FY2019 · DK
DiSCIS Biostatistics and Bioinformatics Core
$273,299Gary R Cutter · University Of Alabama At Birmingham · U19 · FY2017 · AI
Collaborative Research: Creating Synthetic Lichen to Elucidate how Morphology Impacts Mutualistic Exchanges in Microbial Communities.
$273,148Daniel Ducat · Michigan State University · · FY2024 · BIO
Interactive Omics: Black raspberry metabolites and the oral microbiome in smokers
$273,086Christopher M Weghorst · Ohio State University · U01 · FY2017 · CA
Studying Human Gut Microbiome for Osteoporosis Risk
$273,000Hui Shen · Tulane University Of Louisiana · U19 · FY2023 · AG
Local and systemic specific immunity, microbiome and H. pylori infection in child
$272,877Steven J Czinn · University Of Maryland Baltimore · U19 · FY2011 · AI
Project 1: Profiling anti-Ro preclinical and clinical autoimmunity
$272,840Robert M Clancy · New York University School Of Medicine · P50 · FY2018 · AR
Project 5: Microencapsulation Delivery Vehicles for the Implementation of Precision Bioremediation at PAH-Contaminated Superfund Sites
$272,790Claudia Kneller Gunsch · Duke University · P42 · FY2022 · ES
The Lung DNA Virome in Health and Disease
$272,742Ronald G Collman · University Of Pennsylvania · R61 · FY2017 · HL
Microbial Community Analysis Core
$272,664Susan Veronica Lynch · Henry Ford Health System · P01 · FY2014 · AI
In Host Evolution of Nontuberculous Mycobacteria in Cystic Fibrosis
$272,623Paul J Planet · Children'S Hosp Of Philadelphia · R21 · FY2020 · AI
THE USE OF ANTIBIOTICS TO TREAT PATHOGENS IN U.S. FRUIT TREE ORCHARDS HAS GROWN EXPONENTIALLY IN THE LAST DECADE, YET LITTLE IS KNOWN ABOUT ITS EFFECTS ON NON-TARGET ORGANISMS. THIS IS CONCERNING BECAUSE SHORT-TERM EXPOSURE TO ANTIBIOTICS CAN CHANGE THE MICROBIOME--COMMUNITIES OF SYMBIOTIC BACTERIA LIVING WITHIN ANIMALS--OF BENEFICIAL INSECTS, WHICH ARE KNOWN TO MODULATE BEHAVIORS ASSOCIATED WITH INSECT FORAGING. SUCCESSFUL FORAGING IS KEY TO INSECT FITNESS AS WELL AS CROP POLLINATION. MOREOVER, LONG-TERM EXPOSURE TO LOW CONCENTRATIONS OF ANTIBIOTICS MAY DRIVE THE DEVELOPMENT OF ANTIBIOTIC-RESISTANT MICROBIOMES. THIS PROJECT FOCUSES ON THE IMPACT OF CROP ANTIBIOTIC APPLICATIONS ON THE MICROBIOMES AND FORAGING BEHAVIOR OF BEES. FORAGING AND MICROBIOME DATA FROM FIELD EXPERIMENTS IN PEAR(PYRUS COMMUNIS) ORCHARDS--A CROP HIGHLY DEPENDENT ON POLLINATORS FOR FRUIT SET AND THAT REQUIRES ANTIBACTERIAL SPRAYS AT BLOOM--WILL BE PAIRED WITH LABORATORY ASSAYS, FOCUSED ON LINKING BEE GUT MICROBIOMES TO FORAGING BEHAVIOR. SPECIFICALLY, WE WILL 1) QUANTIFY TRACES OF ANTIBIOTICSIN FLOWERS AND EASTERN BUMBLE BEE (BOMBUS IMPATIENS)COLONIES PLACED IN PEAR ORCHARDS AND ASSESS THE IMPACT ON A) COLONY-LEVEL GUT MICROBIOME COMPOSITION (ABUNDANCE OF CORE BACTERIA TAXA AND ANTIBIOTIC-RESISTANT GENES) AND B) INDIVIDUAL AND COLONY-LEVEL FORAGING; 2) TEST IF GUT MICROBIOME CHANGES ALONE CAN DRIVE INDIVIDUAL CHANGES IN BUMBLE BEE LEARNING, MEMORY, AND FORAGING IN THE LAB. THIS WORK WILL FURTHER OUR UNDERSTANDING OF THE IMPACT OF FIELD ANTIBIOTIC EXPOSURE ON AGRICULTURALLY IMPORTANT INSECTS AND ON THE ROLE OF THE MICROBIOME IN MODULATING POLLINATOR HEALTH.
$272,509Emory University · · FY2022 · National Institute of Food and Agriculture