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10,766 grants matching checkpoint inhibitor

Identifying cellular and molecular signatures from distinct T cell receptor clonotypes associated with favorable immune checkpoint inhibitor responses in HNSCCs

$681,410
Robert L Ferris · University Of Pittsburgh At Pittsburgh · R01 · FY2023 · DE

The Transmembrane Protein Disulfide Isomerase TMX1 Negatively Regulates Thrombosis

$681,384
David W Essex · Temple Univ Of The Commonwealth · R01 · FY2024 · HL

Metabolic regulation of immunosuppressive myeloid cells in the tumor microenvironment of pancreatic cancer.

$681,198
Yaqing Zhang · University Of Michigan At Ann Arbor · R01 · FY2024 · CA

Radiation-induced translational control of gene expression

$681,047
Philip Tofilon · Division Of Basic Sciences - Nci · ZIA · FY2015 · CA

Selective disruption of histone deacetylase complexes using protein interaction modulators

$680,864
Marc Vidal · Dana-Farber Cancer Inst · R01 · FY2022 · CA

Analyses of human T regulatory cells

$680,834
Kwong Yok Tsang · Division Of Basic Sciences - Nci · ZIA · FY2014 · CA

Novel regulatory mechanisms and agonists of STING

$680,598
Xuewu Zhang · Ut Southwestern Medical Center · R01 · FY2023 · CA

Novel regulatory mechanisms and agonists of STING

$680,598
Xuewu Zhang · Ut Southwestern Medical Center · R01 · FY2025 · CA

Targeting FGFR Alterations in Gastroesophageal Cancer

$680,532
Sandra W Ryeom · Columbia University Health Sciences · R01 · FY2025 · CA

Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity

$680,292
Sharon S Evans · Roswell Park Cancer Institute Corp · R01 · FY2023 · CA

Drug eluting injectable biomaterials for next generation chemoembolization

$680,198
Rahmi Oklu · Mayo Clinic Arizona · R01 · FY2021 · CA

Selective disruption of histone deacetylase complexes using protein interaction modulators

$680,126
Marc Vidal · Dana-Farber Cancer Inst · R01 · FY2025 · CA

Evaluating and Optimizing Novel nSMase2 Inhibitors in the Treatment of Cancers

$680,034
Robert H Blelloch · University Of California, San Francisco · R01 · FY2025 · CA

Variation in tumor-associated immune profiles and colorectal cancer outcomes

$679,508
Stephanie L. Schmit · Cleveland Clinic Lerner Com-Cwru · R01 · FY2025 · CA

Enabling the therapeutic delivery for spinal cord glioma by epidural light-guided modulation of blood-spinal-cord barrier

$679,176
Zhenpeng Qin · University Of Texas Dallas · R01 · FY2025 · CA

Immunoregulatory role of lung-resident club cell factors in lung cancer

$679,154
Vivek Mittal · Weill Medical Coll Of Cornell Univ · R01 · FY2025 · CA

Immunoregulatory role of lung-resident club cell factors in lung cancer

$679,154
Vivek Mittal · Weill Medical Coll Of Cornell Univ · R01 · FY2023 · CA

Development of Physiologic Tissue Models to Assess Tumor Explant Response to Immune Checkpoint Blockade

$678,954
Roger D. Kamm · Massachusetts Institute Of Technology · U01 · FY2019 · CA

Identifying cellular and molecular signatures from distinct T cell receptor clonotypes associated with favorable immune checkpoint inhibitor responses in HNSCCs

$678,731
Robert L Ferris · University Of Pittsburgh At Pittsburgh · R01 · FY2022 · DE

Proteolysis targeting chimera against nuclear receptor NR4A1 for melanoma therapy

$678,605
Weizhou Zhang · University Of Florida · R01 · FY2024 · CA

Prebiotic diet intervention to enhance the microbiome and immunotherapy response in melanoma

$678,399
Carrie Daniel-Macdougall · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Antidepressant regulation of PDAC

$677,974
Valerie Marie Weaver · University Of California, San Francisco · U01 · FY2025 · CA

Targeting Non Viral Markers of HIV Persistence

$677,623
Timothy Jensen Henrich · University Of California, San Francisco · R01 · FY2021 · AI

Using artificial intelligence to discover spatial, genomic, and pathologic biomarkers to guide and augment immune checkpoint inhibitor therapy for gastric cancer

$677,533
Sam C. Wang · Ut Southwestern Medical Center · R01 · FY2024 · CA

Development of novel human Fab probes for PET imaging of macrophages

$677,520
Bernadette Marquez-Nostra · Yale University · R01 · FY2022 · EB