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17,054 grants matching genome editing

Non-coding genetic variants that impact immune phenotypes and diseases

$870,349
Nir Hacohen · Broad Institute, Inc. · R01 · FY2017 · HG

Optimization of CRISPR genome editor and its delivery strategy for C9orf72 frontotemporal dementia

$869,959
Claire Clelland · University Of California, San Francisco · U01 · FY2023 · NS

Modeling the complex genetics of congenital heart disease in mice

$869,921
Cecilia W. Lo · University Of Pittsburgh At Pittsburgh · R01 · FY2019 · HL

Development of 211Astatine-Conjugated Anti-CD45 Antibody-Based Conditioning for Hematopoietic Stem Cell Gene Therapy and Editing

$869,409
Roland Bruno Walter · Fred Hutchinson Cancer Center · R01 · FY2022 · HL

The Center for Actionable Variant Analysis; measuring variant function at scale

$869,146
Lea Starita · University Of Washington · UM1 · FY2021 · HG

Mechanistic Investigation of RNA-Mediated Gene Regulation and Immunity

$868,299
Ailong Ke · Cornell University · R35 · FY2021 · GM

Impact of Coding Variation on Transcription Factor - DNA Recognition

$867,757
Martha L Bulyk · Brigham And Women'S Hospital · R01 · FY2021 · HG

Elucidating a microgliaassociated role for SORLA in modulating AD pathogenesis

$867,404
Timothy Yikai Huang · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2025 · AG

Rectifying splicing mutations in blood disorders by gene editing

$866,772
Daniel Evan Bauer · Boston Children'S Hospital · R01 · FY2021 · HL

Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

$866,189
James Even Voss · Scripps Research Institute, The · R01 · FY2024 · AI

Project 1: CRISPR screens to discover regulators of CD8 and CD4 cell fates and function

$865,355
Arlene H Sharpe · Harvard Medical School · U19 · FY2021 · AI

Relating Drugs to Genotypes to Transform Precision Cancer Therapeutics with Tuba-seq - a Novel, Highly Scalable and Quantitative Preclinical Experimental Oncology Platform

$865,070
Ian Paul Winters · D2g Oncology, Inc. · R44 · FY2021 · CA

Resources for Comparative Mendelian Disease Genomics

$864,317
Laura G Reinholdt · Jackson Laboratory · R24 · FY2019 · OD

Lamarck Redux: Transgenerational genetic effects on phenotypes and disease

$864,270
Joseph H. Nadeau · Pacific Northwest Research Institute · DP1 · FY2013 · HD

A 3D zebrafish microanatomical and gene expression atlas for disease modeling

$863,982
Khai C Ang · Pennsylvania State Univ Hershey Med Ctr · R24 · FY2025 · OD

Targeted genetic engineering of B cells to induce protective antibody responses to viral pathogens

$863,175
Jennifer Eileen Adair · Fred Hutchinson Cancer Center · R01 · FY2022 · AI

Monitoring Variation in Mixtures of Long RNAs with End-to-End RT Sequencing

$862,998
Anna Marie Pyle · Yale University · R01 · FY2018 · HG

Monitoring Variation in Mixtures of Long RNAs with End-to-End RT Sequencing

$862,936
Anna Marie Pyle · Yale University · R01 · FY2019 · HG

Genetic Determinants of Epilepsy in Murine Systems

$862,733
Wayne N. Frankel · Columbia University Health Sciences · R37 · FY2019 · NS

Neurotology Program

$862,489
Wade Chien · National Institute On Deafness And Other Communication Disorders · ZIA · FY2017 · DC

A new humanized mouse model to study HBV gene editing

$862,440
Keith R Jerome · Fred Hutchinson Cancer Center · R01 · FY2024 · AI

Development of 211Astatine-Conjugated Anti-CD45 Antibody-Based Conditioning for Hematopoietic Stem Cell Gene Therapy and Editing

$861,939
Roland Bruno Walter · Fred Hutchinson Cancer Center · R01 · FY2023 · HL

Rectifying splicing mutations in blood disorders by gene editing

$861,736
Daniel Evan Bauer · Boston Children'S Hospital · R01 · FY2022 · HL

Minimizing in vivo Drug Tolerance induction in tuberculosis.

$861,173
David G Russell · Rutgers Biomedical And Health Sciences · U19 · FY2025 · AI

Kidney targeted AAV for gene therapy

$859,980
Matthew H Wilson · Vanderbilt University Medical Center · R01 · FY2025 · DK