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10,766 grants matching checkpoint inhibitor

Modulating the PD-1/PD-L1 checkpoint to promote antitumor activity of HER2 CAR T cells in patients with sarcoma

$623,817
Meenakshi G Hegde · Baylor College Of Medicine · R01 · FY2024 · CA

Adoptive T Cell Therapy for Pancreatic Cancer

$623,803
Cassian Yee · University Of Tx Md Anderson Can Ctr · R01 · FY2021 · CA

Adoptive T Cell Therapy for Pancreatic Cancer

$623,803
Cassian Yee · University Of Tx Md Anderson Can Ctr · R01 · FY2019 · CA

Adoptive T Cell Therapy for Pancreatic Cancer

$623,803
Cassian Yee · University Of Tx Md Anderson Can Ctr · R01 · FY2020 · CA

A Quantitative PET/CT Research Resource for Co-Clinical Imaging of Lung Cancer Therapies

$623,787
Paul E Kinahan · University Of Washington · U24 · FY2022 · CA

Innate NLRC4 signaling controls adaptive immune responses

$623,783
Fayyaz S. Sutterwala · Cedars-Sinai Medical Center · R01 · FY2024 · AI

Preclinical and Clinical Models of Drug Induced Kidney Injury

$623,715
Melanie S Joy · University Of Colorado Denver · R01 · FY2025 · CA

Radiogenomic Credentialing of Head and Neck Cancer Models

$623,637
Mukund Seshadri · Roswell Park Cancer Institute Corp · R01 · FY2021 · CA

IDENTIFYING BIOMARKERS AND DISSECTING COMBINATORIAL SYNERGIES TO IMPROVE IMMUNE CHECKPOINT INHIBITOR RESPONSE IN BLADDER CANCER

$623,580
The Cleveland Clinic Foundation · · FY2020 · Defense Health Agency

HLA B44 motif neoepitopes in NSCLC: Evaluating their effects on the TME and adding them to established markers in a model to predict durable benefit from PD- 1 inhibition with and without chemotherapy

$623,527
Edward B Garon · University Of California Los Angeles · R01 · FY2025 · CA

Immunotherapy Modeling in Organoids Co-preserving Tumor and Infiltrating Immune Compartments

$623,480
Calvin J Kuo · Stanford University · R01 · FY2024 · CA

Esophageal Squamous Cell Cancer Initiation and Immune Landscape Remodeling

$623,452
Jae-Il Park · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Metallo-fluorocarbon nanoemulsion for PET detection of cancer inflammation

$622,917
Eric T Ahrens · University Of California, San Diego · R01 · FY2024 · CA

Targeting Non Viral Markers of HIV Persistence

$622,821
Timothy Jensen Henrich · University Of California, San Francisco · R01 · FY2022 · AI

UBR5's mechanisms of action in tumorigenesis and immunoregulation

$622,468
Xiaojing Ma · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · CA

Biomarkers of Response to Immuno-chemotherapy & oliGometastatic Hypofractionated radioTherapy (BRIGHT) for Lung Cancer: Synergy of PET/CT Imaging and Peripheral Blood Assays

$622,286
Stephen R. Bowen · University Of Washington · R01 · FY2022 · CA

Interrogating the role of arachidonic acid metabolism in modulating the tumor immune microenvironment as a novel path to therapeutic intervention

$622,227
Timothy J Yeatman · University Of South Florida · U01 · FY2025 · CA

Towards Translation of MU-CN29: New Therapeutic Nanoparticle for Drug-Resistant NSCLC

$622,068
Raghuraman Kannan · University Of Missouri-Columbia · R01 · FY2022 · CA

A Prospective Cohort Study of Patients with Non-Small Cell Lung Cancer and Multiple Myeloma to Assess the Benefits and Harms Related to Cannabis Use During Treatment

$622,059
Richard T Lee · Beckman Research Institute/City Of Hope · U01 · FY2023 · CA

Tailoring CAR T cell therapy for Hodgkin Lymphoma

$622,000
Barbara Savoldo · Univ Of North Carolina Chapel Hill · R01 · FY2022 · CA

preclinical optimization of BCMA directed T cell therapy

$621,878
Marta Chesi · Mayo Clinic Arizona · R01 · FY2025 · CA

Glycosylation and Immune Evasion in Urologic Tumors

$621,878
Sharon Pitteri · Stanford University · U01 · FY2019 · CA

preclinical optimization of BCMA directed T cell therapy

$621,878
Marta Chesi · Mayo Clinic Arizona · R01 · FY2023 · CA

Unique targeting of PPARβ/δ regulation for cancer prevention and therapy

$621,867
Jeffrey M Peters · Pennsylvania State University, The · R01 · FY2024 · CA

Resistance mechanisms to autophagy-modulating therapies

$621,660
Ravi K Amaravadi · University Of Pennsylvania · R01 · FY2024 · CA