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10,766 grants matching checkpoint inhibitor

Radiation and dendritic cell combination to improve immunotherapy response in intrahepatic cholangiocarcinoma

$610,890
Sean S Park · Mayo Clinic Rochester · R01 · FY2024 · CA

Radiation and dendritic cell combination to improve immunotherapy response in intrahepatic cholangiocarcinoma

$610,890
Sean S Park · Mayo Clinic Rochester · R01 · FY2025 · CA

Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response

$610,792
Jeremiah Allen Johnson · Massachusetts Institute Of Technology · R01 · FY2023 · CA

Novel gene delivery to modulate the tumor microenvironment and antigen-specific antitumor immunity

$610,783
Shu-Hsia Chen · Methodist Hospital Research Institute · R01 · FY2024 · CA

Novel gene delivery to modulate the tumor microenvironment and antigen-specific antitumor immunity

$610,783
Shu-Hsia Chen · Methodist Hospital Research Institute · R01 · FY2025 · CA

Pan-Cancer characterization of 3’UTR somatic mutations controlling tumor immune evasion

$610,423
Ioannis Vlachos · Beth Israel Deaconess Medical Center · R01 · FY2023 · CA

Development of small molecule selective inhibitors of neuronal nitric oxide synthase (nNOS) for melanoma treatment

$610,415
Sun Yang · Chapman University · R01 · FY2025 · CA

Identification of small molecule inhibitors to exonuclease 1 for breast cancer treatment

$609,851
Binghui Shen · Beckman Research Institute/City Of Hope · U01 · FY2024 · CA

Tumor Endothelial Cell Regulation of Pro-Metastatic Fibrin Matrices

$609,743
Chad V Pecot · Univ Of North Carolina Chapel Hill · R01 · FY2021 · CA

Immunogen design and testing

$609,490
Barton F Haynes · University Of Pennsylvania · P01 · FY2020 · AI

Radioimmunogenomic Habitat Phenotypes to Predict Efficacy of Neoadjuvant Immunotherapies in Non-Small Cell Lung Cancer

$609,048
Jia Wu · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Identification of pathways to mitigate Immune-Related Adverse Events with Cancer Immunotherapy

$608,731
Donald Ym Leung · National Jewish Health · U01 · FY2024 · AR

Overcoming Hypoxic Resistance in Non-Small Cell Lung Cancer By Targeting Mitochondrial Metabolism

$608,669
Nicholas C Denko · Ohio State University · R01 · FY2024 · CA

The Microbiome and Mucosal Immunity in Cervical Cancer Disparities

$608,613
Adam Burgener · Case Western Reserve University · R01 · FY2025 · CA

Biomarkers of Response to Immuno-chemotherapy & oliGometastatic Hypofractionated radioTherapy (BRIGHT) for Lung Cancer: Synergy of PET/CT Imaging and Peripheral Blood Assays

$608,411
Stephen R. Bowen · University Of Washington · R01 · FY2025 · CA

Immunogen design and testing

$608,337
Barton F Haynes · University Of Pennsylvania · P01 · FY2021 · AI

HIFU-immunotherapy in pancreatic cancer

$608,025
Katherine W Ferrara · Stanford University · R01 · FY2023 · CA

SynerGel: A Novel Tumor Microenvironment-Modulating Hydrogel for Local Immunotherapy

$607,926
Simon Young · University Of Texas Hlth Sci Ctr Houston · R01 · FY2022 · DE

(PQ6) Mesenchymal stem cell based and immunocompetent mouse models of HIV/AIDS KSHV-driven sarcomagenesis

$607,897
Noula Dattu Shembade · University Of Miami School Of Medicine · R01 · FY2024 · CA

Understanding IDH mutant gliomas

$607,784
Jing Wu · Division Of Basic Sciences - Nci · ZIA · FY2019 · CA

Targeting tumor metabolism and immune environment via beta-catenin: Towards precision medicine in HCC

$607,771
Satdarshan Singh Monga · University Of Pittsburgh At Pittsburgh · R01 · FY2023 · CA

Targeting tumor metabolism and immune environment via beta-catenin: Towards precision medicine in HCC

$607,766
Satdarshan Singh Monga · University Of Pittsburgh At Pittsburgh · R01 · FY2022 · CA

Mechanisms of BET bromodomain metabolic reprogramming in triple negative breast cancer

$607,228
Gerald V Denis · Boston University Medical Campus · R01 · FY2022 · CA

A phase I/II study of combined therapy with Th17-inducing dendritic cells and pembrolizumab in patients with recurrent epithelial ovarian cancer

$607,154
Keith L Knutson · Mayo Clinic Jacksonville · R01 · FY2024 · CA

Improving Pediatric Melanoma Outcomes in a Longitudinally Evaluated Cohort

$607,140
Marielle Yohe · Division Of Basic Sciences - Nci · ZIA · FY2025 · CA