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10,766 grants matching checkpoint inhibitor

Novel therapeutic approaches for enhancing anti-tumor immunity in SCLC

$596,039
John V. Heymach · University Of Tx Md Anderson Can Ctr · U01 · FY2018 · CA

The Genetics of Ocular Melanoma

$596,016
Anne Mary Bowcock · Icahn School Of Medicine At Mount Sinai · R01 · FY2024 · CA

Bottlebrush polymer prodrugs for targeted delivery of combination therapies and in vivo imaging of pharmacological response

$595,926
Jeremiah Allen Johnson · Massachusetts Institute Of Technology · R01 · FY2025 · CA

Engineering immunotherapeutic probiotics to mitigate irAE

$595,682
Tal Danino · Columbia Univ New York Morningside · U01 · FY2021 · CA

Cardioprotective Therapy for Doxorubicin Using iPSC Microtissue and CRISPR Screening

$595,679
Joseph C Wu · Stanford University · R01 · FY2023 · HL

Elucidating the Immune Suppressive Mechanism of SIGLEC-15 in the Tumor Microenvironment

$595,576
Jun Wang · New York University School Of Medicine · R01 · FY2023 · CA

An urinary drug disposing approach for treatment of bladder Cancer

$595,483
Benedict Shek Hang Law · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · CA

Mouse models of Kras-mutant colorectal cancer

$595,434
Kevin Michael Haigis · Dana-Farber Cancer Inst · R01 · FY2024 · CA

Immunogenomic predictors of outcomes in patients with locally advanced cervical cancer treated with immunotherapy and chemoradiation

$595,374
Dmitriy Zamarin · Icahn School Of Medicine At Mount Sinai · R01 · FY2023 · CA

Molecular Pathways Regulating Tissue-resident Memory T cells in the Gut

$595,247
Michael Lawrence Dougan · Massachusetts General Hospital · R01 · FY2023 · AI

Molecular Pathways Regulating Tissue-resident Memory T cells in the Gut

$595,247
Michael Lawrence Dougan · Massachusetts General Hospital · R01 · FY2025 · AI

Molecular Pathways Regulating Tissue-resident Memory T cells in the Gut

$595,247
Michael Lawrence Dougan · Massachusetts General Hospital · R01 · FY2024 · AI

Phase I therapeutic testing of viral-vectored vaccines that shift CD8+ T cell immunodominance to conserved regions of HIV-1

$594,846
Nilu Goonetilleke · Univ Of North Carolina Chapel Hill · U01 · FY2022 · AI

Genetically-engineered Bacteria Overcome Therapy Resistance

$594,699
Ralph R Weichselbaum · University Of Chicago · R01 · FY2025 · CA

Reorienting the Glioblastoma Microenvironment to Respond to Immunotherapy

$594,636
Mary Helen Barcellos-Hoff · University Of California, San Francisco · R01 · FY2019 · NS

Rational targeting of Cdc42 to benefit immunotherapy

$594,402
Yi Zheng · Cincinnati Childrens Hosp Med Ctr · R01 · FY2024 · CA

Rational targeting of Cdc42 to benefit immunotherapy

$594,402
Yi Zheng · Cincinnati Childrens Hosp Med Ctr · R01 · FY2025 · CA

Targeting GRP94-TGF-beta Pathway for Cancer Immunotherapy

$594,336
Zihai Li · Ohio State University · R01 · FY2022 · CA

Ablating Liver Metastases with SBRT to Enhance Immune Checkpoint Blockade in Melanoma

$594,335
Michael Daniel Green · University Of Michigan At Ann Arbor · R01 · FY2023 · CA

Cancer immunotherapy

$594,136
Eytan Ruppin · Division Of Basic Sciences - Nci · ZIA · FY2018 · CA

RIG-I Activating Nanoparticles for Immunopotentiation

$594,047
John Tanner Wilson · Vanderbilt University · R01 · FY2023 · EB

Cachexia-mediated FcRn Modulation and Its Impact on Anti-PD1 Therapy in Lung Cancer

$594,010
Mitch A Phelps · Ohio State University · R01 · FY2024 · CA

Multiscale analysis of metabolic inflammation as a driver of breast cancer

$593,459
Gerald V Denis · Boston University Medical Campus · U01 · FY2020 · CA

Molecular and immunological heterogeneity of Small Cell Lung Cancer (SCLC) and its impact on relapse and therapeutic response

$593,411
Lauren Averett Byers · University Of Tx Md Anderson Can Ctr · U01 · FY2022 · CA

Ascorbic acid as a pharmacologic agent in disease treatment

$593,140
Mark A Levine · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2023 · DK