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15,440 grants matching organoids

Analyzing the Hypersensitivity of MMR-deficient Colorectal Cancers to mTOR Inhibition and the Response of Cancer Stem Cells

$404,847
Winfried Edelmann · Albert Einstein College Of Medicine · R01 · FY2025 · CA

Targeting aberrant enhancer landscapes in pancreatic cancer

$404,792
Christopher Vakoc · Cold Spring Harbor Laboratory · R01 · FY2023 · CA

Targeting aberrant enhancer landscapes in pancreatic cancer

$404,792
Christopher Vakoc · Cold Spring Harbor Laboratory · R01 · FY2022 · CA

New sterol-binding targets and optimized EBP inhibitors for promoting remyelination

$404,785
Drew James Adams · Case Western Reserve University · R01 · FY2023 · NS

New sterol-binding targets and optimized EBP inhibitors for promoting remyelination

$404,785
Drew James Adams · Case Western Reserve University · R01 · FY2022 · NS

Project 1: Interrogating Distinct Tumor-Initiating Cells in CRC

$404,764
Robert J Coffey · Vanderbilt University Medical Center · P50 · FY2020 · CA

Targeting cysteine import to induce ferroptotic cell death in pancreatic cancer

$404,558
Kenneth P Olive · Columbia University Health Sciences · R01 · FY2017 · CA

Role of type 2 immune response in pancreatic cancer tumorigenesis

$404,550
Prasenjit Dey · Roswell Park Cancer Institute Corp · R01 · FY2025 · CA

SOX4-Mediated Transcription Program in Esophageal Adenocarcinoma

$404,394
Jianwen Que · University Of Miami School Of Medicine · P01 · FY2025 · CA

Elucidating the Role of Very-long-chain Polyunsaturated Fatty Acids in Retinal Health and Disease

$404,375
Paul Steven Bernstein · University Of Utah · R01 · FY2023 · EY

Understanding Down Syndrome Brain Development Using Human iPSC-Based Mouse Chimeras

$404,253
Peng Jiang · Rutgers, The State Univ Of N.J. · R01 · FY2024 · NS

Exploring Margaric Acid Role in Alcohol-Associated Liver Diseases

$404,250
Radhakrishna Rao · University Of Tennessee Health Sci Ctr · R21 · FY2025 · AA

Project 3: Functional Genomic Mechanisms of Epithelial Dysfunction in Pulmonary Fibrosis

$404,240
Jonathan Andrew Kropski · University Of Michigan At Ann Arbor · P01 · FY2025 · HL

Decoding the Mechanism of Pathogenic Enhancer Mutations In Congenital Limb Disorders

$404,190
Evgeny Kvon · University Of California-Irvine · R01 · FY2025 · HD

Biochemistry of SARS-CoV-2 Spike Protein and its Ocular Surface Membrane Receptor

$404,162
T. Michael Redmond · National Eye Institute · ZIA · FY2023 · EY

Understanding Resistance to Next Generation Antiandrogens

$404,100
Charles L Sawyers · Sloan-Kettering Inst Can Research · R01 · FY2020 · CA

Understanding Resistance to Next Generation Antiandrogens

$404,100
Charles L Sawyers · Sloan-Kettering Inst Can Research · R01 · FY2021 · CA

Investigation and Translation of the Intestinal Stem Cell Niche

$404,070
Calvin J Kuo · Stanford University · U01 · FY2023 · DK

A novel approach to restore functional TDP43 for the treatment of FTD and ALS

$404,058
Jonathan N Sachs · University Of Minnesota · R21 · FY2025 · AG

Project 3 - Development of serine/threonine phosphatase PP2A molecular glues for the treatment of advanced prostate cancer

$404,043
Goutham Narla · University Of Michigan At Ann Arbor · P50 · FY2025 · CA

Uncovering the Mechanisms of Metastasis in Fallopian Tube-Originated Ovarian Cancer

$403,851
Yang Yang-Hartwich · Yale University · R01 · FY2024 · CA

Exploring Wnt-Fzd signaling specificities

$403,819
Karl H Willert · University Of California, San Diego · R35 · FY2020 · GM

Investigation and Translation of the Intestinal Stem Cell Niche

$403,787
Calvin J Kuo · Stanford University · U01 · FY2022 · DK

Mechanistic analysis and allellic genome editing of iPSC-derived dominant LCA model

$403,750
Erik M Ullian · University Of California, San Francisco · R01 · FY2025 · EY

The roles of regional specialization, mechanical forces and epigenetic memory after perturbation and injury of the intestinal stem cell microenvironment

$403,750
Ophir D Klein · University Of California, San Francisco · U01 · FY2020 · DK