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15,440 grants matching organoids

Quantitative Computational Methods to Accurately Measure Tumor Heterogeneity in Solid Tumors to Inform Development of Evolution-based Treatment Strategies

$363,370
Jeffrey Hsu-Min Chuang · Jackson Laboratory · R01 · FY2022 · CA

H pylori-host Interactions

$363,366
Yana Zavros · University Of Cincinnati · U19 · FY2016 · AI

Epigenomic control of antimicrobial immunity in the intestine

$363,361
Theresa Alenghat · Cincinnati Childrens Hosp Med Ctr · R01 · FY2019 · DK

(PQ4) - Tools for simultaneous disruption of multiple epigenetically silenced genes for studying their roles in tumorigenesis using ex vivo human and mouse colon organoid and in vivo mouse models

$363,340
Hariharan Easwaran · Johns Hopkins University · R01 · FY2019 · CA

Generation of T-cell receptors recognizing antigens on non-melanoma tumors

$363,308
James C Yang · Division Of Basic Sciences - Nci · ZIA · FY2020 · CA

Investigating the molecular mechanisms of growth in GNAS mutant pancreatic cancer.

$363,164
Krushna Chandra Patra · University Of Cincinnati · R37 · FY2023 · CA

Role of CCN6 (WISP3) in the progression and metastasis of breast cancer

$363,090
Celina G Kleer · University Of Michigan At Ann Arbor · R01 · FY2022 · CA

Project 4 Dissecting the Role of Revival Stem Cells and Tuft Cells in the Radiation-Induced Gastrointestinal Syndrome to Define Targets for Mitigation

$362,979
David G Kirsch · Duke University · U19 · FY2020 · AI

Project 2: Translational Significance of a Mutational Signature of African American Colon Cancers

$362,917
Joseph Edward Willis · Case Western Reserve University · P50 · FY2020 · CA

The role of type 2 inflammation in the initiation and progression of metaplastic differentiation and neoplastic transformation of gastric epithelia

$362,902
Zhibin Chen · University Of Miami School Of Medicine · R01 · FY2020 · CA

Targeting oncogenic epigenetic mechanisms in IDHmut/ATRXloss Astrocytoma

$362,823
Yunqing Li · Hugo W. Moser Res Inst Kennedy Krieger · R01 · FY2024 · NS

Lineage specifiers governing pancreatic cancer growth and molecular subtype

$362,818
Eric Lee Snyder · University Of Utah · R01 · FY2020 · CA

Microfluidic platform for solid tumor mechanics and invasion

$362,800
Mingming Wu · Cornell University · R01 · FY2023 · CA

A20 Mediated Regulation of Colitis and Spondyloarthritis

$362,625
Averil I Ma · University Of California, San Francisco · R01 · FY2020 · DK

Role of PD2/Paf1 in Pancreatic Acinar to Ductal Metaplasia

$362,607
Moorthy P. Ponnusamy · University Of Nebraska Medical Center · R01 · FY2019 · CA

Modulating HSP70/STUB1 machinery in therapy-resistant prostate cancer

$362,398
Chengfei Liu · University Of California At Davis · R01 · FY2022 · CA

Modulating HSP70/STUB1 machinery in therapy-resistant prostate cancer

$362,334
Chengfei Liu · University Of California At Davis · R01 · FY2021 · CA

Networks for functional regulation of pancreatic acinar-ductal metaplasia and epithelial plasticity

$362,250
Anil K Rustgi · University Of Pennsylvania · R01 · FY2017 · DK

Aldh2 and mitochondrial homeostasis in esophageal pathobiology

$362,250
Hiroshi Nakagawa · University Of Pennsylvania · R01 · FY2018 · AA

Networks for functional regulation of pancreatic acinar-ductal metaplasia and epithelial plasticity

$362,250
Anil K Rustgi · University Of Pennsylvania · R01 · FY2016 · DK

Engineering Extracellular Vesicles of Human Brain Organoids for Stroke Therapy

$362,156
Yan Li · Florida State University · R01 · FY2022 · NS

MECHANOSURVEILLANCE IN BREAST CANCER METASTASIS

$362,132
Ekrem Emrah Er · University Of Illinois At Chicago · R37 · FY2025 · CA

MECHANOSURVEILLANCE IN BREAST CANCER METASTASIS

$362,132
Ekrem Emrah Er · University Of Illinois At Chicago · R37 · FY2022 · CA

Montreal-Boston Collaborative GRC

$361,767
John D. Rioux · Montreal Heart Institute · U01 · FY2022 · DK

Role of the complement C3a receptor on immune and non immune intestinal barrier functions and microbiota in colorectal cancer development

$361,672
Silvia Guglietta · Medical University Of South Carolina · R01 · FY2022 · CA