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15,440 grants matching organoids

Non-coding RNAs in resilience to Alzheimer’s Disease

$827,394
Frank J. Slack · Beth Israel Deaconess Medical Center · R01 · FY2025 · AG

Function interactions between mitogen-activated protein kinases (MAPKs) and SARS-CoV-2

$827,164
Jeffrey R Johnson · Icahn School Of Medicine At Mount Sinai · R01 · FY2025 · AI

Fibroblast orchestration of the immune response in pancreatic cancer

$826,873
Marina Pasca Di Magliano · University Of Michigan At Ann Arbor · U01 · FY2025 · CA

Targeting Arc to Improve Cognitive Deficits in Psychotic Disorders

$826,675
Rakesh Karmacharya · Massachusetts General Hospital · R01 · FY2024 · MH

Extracellular vesicles in Environmental Epidemiology Studies of Aging

$826,656
Andrea Baccarelli · Harvard University D/B/A Harvard School Of Public Health · R35 · FY2024 · ES

Development of Physiologic Tissue Models to Assess Tumor Explant Response to Immune Checkpoint Blockade

$826,420
Roger D. Kamm · Massachusetts Institute Of Technology · U01 · FY2021 · CA

cGAS-STING mediated neuroinflammation in Alzheimer's disease

$826,222
Zhen Zhao · University Of Southern California · R56 · FY2023 · AG

Research Project 1: Identification and validation of efficacious therapies for breast cancer using patient-derived specimens

$825,486
Alana L Welm · University Of Utah · U54 · FY2017 · CA

Targeting Arc to Improve Cognitive Deficits in Psychotic Disorders

$825,005
Rakesh Karmacharya · Massachusetts General Hospital · R01 · FY2025 · MH

IDENTIFICATION OF MECHANOTRANSDUCTION MECHANISMS LEADING TO NEURONAL INJURY IN CEREBRAL ORGANOIDS. NEW AWARD.

$825,001
University Of Southern California · · FY2020 · Department of the Army

Prospective Epidemiologic Study of Novel Etiologic Agents of Pelvic Inflammatory Disease

$824,632
Catherine L Haggerty · University Of Pittsburgh At Pittsburgh · R01 · FY2022 · AI

CSHL-JAX Patient-Derived Models of Pancreatic Cancer as Systems for Investigating Tumor Heterogeneity

$823,816
David Tuveson · Cold Spring Harbor Laboratory · U01 · FY2022 · CA

Genetically Diverse Mouse Embryonic Stem Cells: A Platform for Cellular Systems Genetics

$823,759
Laura G Reinholdt · Jackson Laboratory · R24 · FY2021 · OD

Role of histone variants in aging and cancer

$822,934
Yamini P Dalal · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA

Longitudinal models of breast cancer for studying mechanisms of therapy response and resistance

$822,738
Bryan E. Welm · University Of Utah · U01 · FY2018 · CA

The Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CD-GEMM) Prospective Cohort Study

$822,642
Alessio Fasano · Massachusetts General Hospital · R56 · FY2023 · AI

Understanding Mechanisms and Sex-Differences in Visceral Pain

$822,501
Holly A. Ingraham · University Of California, San Francisco · R01 · FY2024 · DK

Cell-cell and cell-matrix interactions driving progressive fibrosis in interstitial lung diseases

$822,275
Brigitte N Gomperts · University Of California Los Angeles · U01 · FY2024 · HL

Identifying and modeling immune correlates of protection against congenital CMV transmission after primary maternal infection

$822,260
Sallie R. Permar · Weill Medical Coll Of Cornell Univ · R01 · FY2024 · AI

Personalized cancer models to discover and develop new therapeutic targets.

$821,431
Christopher J Kemp · Fred Hutchinson Cancer Research Center · U01 · FY2019 · CA

Transcriptomics-based identification of cell type specific host genes and gene networks perturbed by HSV-1 in cerebral organoids.

$820,743
Teng-Ting Elaine Lim · Univ Of Massachusetts Med Sch Worcester · R01 · FY2025 · AG

Examining the effect of cadmium metal exposure on Alzheimer's disease genetic alleles using herpes viral infected cerebral organoids

$820,735
Ying Leong Chan · Univ Of Massachusetts Med Sch Worcester · U01 · FY2025 · AG

DNA-damage-induced transcription errors provide a constant stream of amyloid and prion-like proteins in human cells

$820,674
Marc Vermulst · University Of Southern California · R01 · FY2024 · AG

Genetic determinates of SPI1 expression and activity in human germinal center B cells

$820,623
Neil David Romberg · Children'S Hosp Of Philadelphia · R01 · FY2025 · AI

Genetics-informed dissection of human brain cell-cell communication in Alzheimer's disease progression

$820,536
Bingshan Li · Vanderbilt University · R01 · FY2024 · AG