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15,440 grants matching organoids

Functional Characterization and Development of Therapeutic Paradigms for DNA Damage Repair (DDR)-deficient Lethal Prostate Cancer

$729,450
Goutam Chakraborty · Icahn School Of Medicine At Mount Sinai · R01 · FY2023 · CA

Mechanisms of mitochondria-driven hepatocyte injury

$729,085
Dipayan Chaudhuri · Utah State Higher Education System--University Of Utah · R01 · FY2025 · DK

Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progression

$729,080
Shuibing Chen · Weill Medical Coll Of Cornell Univ · R01 · FY2023 · DK

Targeted Therapy in Neuroendocrine Cancer

$729,053
Samira Sadowski · Division Of Basic Sciences - Nci · ZIA · FY2019 · CA

Overcoming adaptive feedback resistance to KRAS inhibition in colorectal cancer

$728,990
Ryan Bruce Corcoran · Massachusetts General Hospital · R01 · FY2022 · CA

Uncovering the Biology of Resistance to Tyrosine Kinase Inhibitors in EGFR Mutant Lung Cancer Patient-Derived Models.

$728,983
Katerina Abigail Politi · Yale University · U01 · FY2023 · CA

Enhance UCSC Xena: extend interactive visualization to ultra-large-scale multi-omics data and integrate with analysis resources

$728,574
Jingchun Zhu · University Of California Santa Cruz · U24 · FY2024 · CA

RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis

$728,332
Joseph Heitman · Duke University · R01 · FY2025 · AI

The role of CD73 in esophageal epithelial homeostasis

$728,143
Amanda Brooke Muir · Children'S Hosp Of Philadelphia · R01 · FY2025 · DK

Molecular basis of action and pathogenesis of Clostridium difficile toxin B

$727,954
Min Dong · Boston Children'S Hospital · R01 · FY2019 · AI

Engineered probiotic bacteria for colorectal cancer immunoprevention and interception

$727,904
Nicholas Arpaia · Columbia University Health Sciences · UG3 · FY2025 · CA

Single-cell multi-region dissection of AD-pathogen interactions for HSV-1 and CMV

$727,847
Manolis Kellis · Massachusetts Institute Of Technology · R01 · FY2025 · AG

Functional Biointegration of Bioengineered Salivary Tissues in Irradiated Animal Models

$727,581
Mary C Farach-Carson · University Of Texas Hlth Sci Ctr Houston · R01 · FY2022 · DE

Development of CRISPR/Cas9-based exon-skipping strategies for the treatment of USH-associated deafness

$727,454
Xue Z Liu · University Of Miami School Of Medicine · R01 · FY2022 · DC

Multimodal Microscope for Live Cell Molecular Dynamics

$727,298
Timothy Stasevich · Colorado State University · S10 · FY2025 · OD

Dissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.

$726,976
Sofie Reda Salama · University Of California Santa Cruz · R01 · FY2022 · MH

Dissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.

$726,976
Sofie Reda Salama · University Of California Santa Cruz · R01 · FY2024 · MH

Dissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.

$726,976
Sofie Reda Salama · University Of California Santa Cruz · R01 · FY2021 · MH

Dissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.

$726,976
Sofie Reda Salama · University Of California Santa Cruz · R01 · FY2023 · MH

RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis

$726,611
Joseph Heitman · Duke University · R01 · FY2024 · AI

Advancing the development of a novel class of small molecules for treating pan-coronavirus infections

$726,503
Shirit Einav · Stanford University · R01 · FY2024 · AI

The Role of Renal Interstitium in Kidney Development

$726,394
Thomas Joseph Carroll · Ut Southwestern Medical Center · R01 · FY2021 · DK

Tailoring Novel Therapeutics for Emerging Drug-Resistant C. Difficile Colitis

$726,199
Richard L Guerrant · University Of Virginia · U01 · FY2010 · AI

Universal Influenza Vaccines (UIV)

$725,497
Heinrich Feldmann · National Institute Of Allergy And Infectious Diseases · ZIA · FY2025 · AI

Functional validation of sequence variants affecting neurodevelopmental and craniofacial phenotypes

$725,353
Victor G. Corces · Emory University · R56 · FY2022 · DE